AutismKB 2.0

Annotation Detail for CREB3L2


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Basic Information Top
Gene Symbol:CREB3L2 ( BBF2H7,MGC131709,MGC71006 )
Gene Full Name: cAMP responsive element binding protein 3-like 2
Band: 7q33
Quick LinksEntrez ID:64764; OMIM: 608834; Uniprot ID:CR3L2_HUMAN; ENSEMBL ID: ENSG00000182158; HGNC ID: 23720
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
191Phosphoserine.
480N-linked (GlcNAc...) (Potential).
504N-linked (GlcNAc...) (Potential).
517N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
191Phosphoserine.Swiss-Prot 53.0
480N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
504N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
517N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
19Phosphoserine(PKG)HMM predict
19Phosphoserine(CK2)HMM predict
22Phosphoserine(CK1)HMM predict
44Phosphoserine(ATM)HMM predict
69Phosphoserine(IKK)HMM predict
69Phosphoserine(CDC2)HMM predict
69O-linkedHMM predict
69Phosphoserine(ATM)HMM predict
71Phosphothreonine(PKC)HMM predict
72O-linkedHMM predict
72Phosphoserine(MAPK)HMM predict
72Phosphoserine(IKK)HMM predict
72Phosphoserine(CDC2)HMM predict
103Phosphoserine(CK2)HMM predict
111Phosphoserine(CK1)HMM predict
145O-linkedHMM predict
151Phosphothreonine(MAPK)HMM predict
151Phosphothreonine(CDK)HMM predict
191Phosphoserine(CDC2)HMM predict
205Phosphothreonine(MAPK)HMM predict
205PhosphothreonineHMM predict
205Phosphothreonine(CDK)HMM predict
208Phosphoserine(CK2)HMM predict
209O-linkedHMM predict
212Phosphoserine(ATM)HMM predict
217O-linkedHMM predict
219Phosphoserine(ATM)HMM predict
219Phosphoserine(CDC2)HMM predict
219Phosphoserine(CDK)HMM predict
228O-linkedHMM predict
234PhosphoserineHMM predict
234Phosphoserine(IKK)HMM predict
234Phosphoserine(CDC2)HMM predict
234Phosphoserine(CDK)HMM predict
236O-linkedHMM predict
244O-linkedHMM predict
244Phosphoserine(IKK)HMM predict
248O-linkedHMM predict
249Phosphoserine(IKK)HMM predict
307Phosphoserine(PKG)HMM predict
347N-linkedHMM predict
411Phosphoserine(ATM)HMM predict
414Phosphoserine(IKK)HMM predict
442Phosphoserine(CK1)HMM predict
443Phosphoserine(ATM)HMM predict
443Phosphoserine(CDC2)HMM predict
443O-linkedHMM predict
480N-linkedHMM predict
483Phosphoserine(CK1)HMM predict
504N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_194071
  • Location:chr7 137210266-137337385
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 137344192 137344383 191 6902
CTCF CD4SISSRdata 137344192 137344383 191 6902
CTCF G2GSE9613 137337398 137338177 779 402
CTCF G2GSE9613 137343940 137344343 403 6756
hScc1 BcellGSE12603 137343940 137344343 403 6756
hScc1 CdLSGSE12603 137337502 137337933 431 332
hScc1 CdLSGSE12603 137343940 137344343 403 6756
hScc1 G2GSE9613 137343940 137344343 403 6756
p130 SenescentGSE19898 137337168 137337978 810 188
p130 shRbQuiescentGSE19898 137337117 137337863 746 105
p130 shRbSenescentGSE19898 137337210 137337840 630 140
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 137313405 137314853 1448 0
CTCF CD4GSE12889 137234444 137234676 232 0
CTCF CD4GSE12889 137238872 137239316 444 0
CTCF CD4SISSRdata 137234444 137234676 232 0
CTCF CD4SISSRdata 137238872 137239316 444 0
CTCF HelaGSE12889 137234445 137234820 375 0
CTCF JurkatGSE12889 137234455 137234693 238 0
CTCF G2GSE9613 137221568 137221924 356 0
CTCF G2GSE9613 137234461 137234925 464 0
CTCF G2GSE9613 137238735 137239472 737 0
CTCF G2GSE9613 137244778 137245019 241 0
CTCF G2GSE9613 137247165 137247340 175 0
CTCF G2GSE9613 137313800 137314176 376 0
CTCF G2GSE9613 137319234 137319431 197 0
CTCF G2GSE9613 137331722 137331897 175 0
ER MCF7GSE19013 137314386 137315255 869 0
FOXA1 MCF7GSE15244 137283321 137284932 1611 0
FOXA1 MCF7GSE15244 137288415 137290652 2237 0
FOXA1 MCF7GSE15244 137299659 137299986 327 0
Fos K562GSE19551 137217261 137218075 814 0
Fos K562GSE19551 137313592 137314175 583 0
FoxA1 MCF7MACSdata 137289018 137289659 641 0
Gata2 K562GSE18868 137298004 137298765 761 0
H3K4me2 HCT116GSE10453 137335356 137336655 1299 0
H3K4me3 colorectalcancer 137336189 137336797 608 0
H3ac HepG2E 137324328 137325788 1460 0
H3ac HepG2E 137333054 137333783 729 0
H3ac HepG2E 137334227 137336919 2692 0
NFkBII GM12878GSE19485 137229929 137231857 1928 0
NRSF mAbJurkat 137334893 137335566 673 0
Oct1 HelaGSE14283 137259959 137259986 27 0
Oct1 HelaGSE14283 137320886 137320914 28 0
Oct4 hESGSE17917 137234445 137234924 479 0
P300 T0-glioblastomaGSE21026 137279149 137279980 831 0
P300 T30-glioblastomaGSE21026 137278017 137280124 2107 0
P300 T30-glioblastomaGSE21026 137313478 137314590 1112 0
RARA MCF7GSE15244 137288915 137290023 1108 0
Rb SenescentGSE19898 137234442 137234761 319 0
TAF HelaGSE8489 137334227 137335499 1272 0
TAF HelaGSE8489 137336020 137336762 742 0
TAF k562GSE8489 137335675 137336762 1087 0
TFAP2C MCF7GSE21234 137287549 137288069 520 0
TFAP2C MCF7GSE21234 137299497 137299961 464 0
hScc1 BcellGSE12603 137234461 137234780 319 0
hScc1 BcellGSE12603 137238881 137239508 627 0
hScc1 BcellGSE12603 137335247 137335759 512 0
hScc1 CdLSGSE12603 137234461 137234813 352 0
hScc1 CdLSGSE12603 137238779 137239472 693 0
hScc1 G2GSE9613 137234461 137234780 319 0
hScc1 G2GSE9613 137238696 137239508 812 0
hScc1 G2GSE9613 137335499 137336049 550 0
p130 QuiescentGSE19898 137278604 137278805 201 0
p130 QuiescentGSE19898 137335731 137336061 330 0
p130 SenescentGSE19898 137327972 137328397 425 0
p130 SenescentGSE19898 137335480 137336535 1055 0
p130 shRbQuiescentGSE19898 137328066 137328494 428 0
p63 keratinocytesGSE17611 137325316 137326117 801 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
343 Unknown MicroArray miR-124 CREB3L2 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000182158 G1-to-S transition n_a n_a "leukocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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