AutismKB 2.0

Annotation Detail for FNDC3B


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Basic Information Top
Gene Symbol:FNDC3B ( DKFZp686D14170,DKFZp762K137,FAD104,FLJ23399,MGC10002,PRO4979,YVTM2421 )
Gene Full Name: fibronectin type III domain containing 3B
Band: 3q26.31
Quick LinksEntrez ID:64778; OMIM: 611909; Uniprot ID:FND3B_HUMAN; ENSEMBL ID: ENSG00000075420; HGNC ID: 24670
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
208Phosphoserine.
211Phosphoserine.
1163Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
73N-linkedHMM predict
102Phosphothreonine(CDK)HMM predict
115O-linkedHMM predict
118PhosphoserineHMM predict
141Phosphotyrosine(Syk)HMM predict
187Phosphotyrosine(Syk)HMM predict
187Phosphotyrosine(SRC)HMM predict
208Phosphoserine(MAPK)HMM predict
208Phosphoserine(IKK)HMM predict
208Phosphoserine(CDC2)HMM predict
238O-linkedHMM predict
253PhosphoserineHMM predict
253Phosphoserine(PKB)HMM predict
253Phosphoserine(PKG)HMM predict
254Phosphoserine(CDC2)HMM predict
254Phosphoserine(CDK)HMM predict
257Phosphoserine(IKK)HMM predict
258N-linkedHMM predict
365Phosphoserine(IKK)HMM predict
367Phosphoserine(ATM)HMM predict
371O-linkedHMM predict
405N-linkedHMM predict
411N-linkedHMM predict
553Phosphothreonine(PKC)HMM predict
568Phosphoserine(CDC2)HMM predict
626Phosphoserine(IKK)HMM predict
633PhosphothreonineHMM predict
699Phosphoserine(IKK)HMM predict
721Phosphotyrosine(Syk)HMM predict
751Phosphotyrosine(INSR)HMM predict
762O-linkedHMM predict
793Phosphoserine(ATM)HMM predict
793Phosphoserine(CK2)HMM predict
810Phosphoserine(CK1)HMM predict
848Phosphotyrosine(Jak)HMM predict
878SulfotyrosineHMM predict
881Phosphoserine(CDK)HMM predict
883Phosphoserine(IKK)HMM predict
916N-linkedHMM predict
947Phosphoserine(ATM)HMM predict
1006Phosphoserine(PKA)HMM predict
1015Phosphotyrosine(Syk)HMM predict
1044O-linkedHMM predict
1046O-linkedHMM predict
1048O-linkedHMM predict
1049O-linkedHMM predict
1050O-linkedHMM predict
1052Phosphoserine(IKK)HMM predict
1056O-linkedHMM predict
1099Phosphotyrosine(EGFR)HMM predict
1099Phosphotyrosine(SRC)HMM predict
1099Phosphotyrosine(Syk)HMM predict
1103Phosphotyrosine(Syk)HMM predict
1143Phosphoserine(CDC2)HMM predict
1143Phosphoserine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022763
  • Location:chr3 173241079-173601179
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 173235635 173235874 239 5325
CTCF CD4SISSRdata 173235635 173235874 239 5325
CTCF G2GSE9613 173239991 173241185 1194 492
H3K4me3 colorectalcancer 173239665 173240172 507 1161
H3ac HepG2E 173239665 173240083 418 1206
PHF8 HeLaGSE20725 173239667 173241626 1959 433
Rb GrowingGSE19898 173239898 173240171 273 1045
Rb GrowingGSE19898 173240585 173240812 227 381
Rb QuiescentGSE19898 173239943 173240136 193 1040
Rb shRbQuiescentGSE19898 173240688 173240914 226 279
hScc1 BcellGSE12603 173240083 173240506 423 785
hScc1 G2GSE9613 173239962 173241382 1420 408
p130 QuiescentGSE19898 173239632 173239829 197 1349
p130 QuiescentGSE19898 173240163 173240349 186 824
p130 shRbSenescentGSE19898 173240489 173240842 353 414
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 173532979 173533412 433 0
CTCF CD4GSE12889 173542060 173542237 177 0
CTCF CD4SISSRdata 173532979 173533412 433 0
CTCF CD4SISSRdata 173542060 173542237 177 0
CTCF G2GSE9613 173308108 173308351 243 0
CTCF G2GSE9613 173325563 173325924 361 0
CTCF G2GSE9613 173369572 173369819 247 0
CTCF G2GSE9613 173399035 173399283 248 0
CTCF G2GSE9613 173414747 173414958 211 0
CTCF G2GSE9613 173456588 173456840 252 0
CTCF G2GSE9613 173489999 173490453 454 0
CTCF G2GSE9613 173504545 173504792 247 0
CTCF G2GSE9613 173518397 173518679 282 0
CTCF G2GSE9613 173525270 173525409 139 0
CTCF G2GSE9613 173532817 173533524 707 0
CTCF G2GSE9613 173534136 173534665 529 0
CTCF G2GSE9613 173540402 173540725 323 0
CTCF G2GSE9613 173541706 173541890 184 0
CTCF G2GSE9613 173551705 173551978 273 0
CTCF G2GSE9613 173577249 173577605 356 0
FOXA1 MCF7GSE15244 173330296 173331242 946 0
FOXA1 MCF7GSE15244 173338435 173338825 390 0
FOXA1 MCF7GSE15244 173340961 173341999 1038 0
FOXA1 MCF7GSE15244 173356957 173357519 562 0
FOXA1 MCF7GSE15244 173369500 173370166 666 0
FOXA1 MCF7GSE15244 173380391 173380977 586 0
FOXA1 MCF7GSE15244 173404160 173404847 687 0
FOXA1 MCF7GSE15244 173414112 173415096 984 0
FOXA1 MCF7GSE15244 173485647 173486156 509 0
FOXA1 MCF7GSE15244 173498603 173499427 824 0
FOXA1 MCF7GSE15244 173507679 173507936 257 0
FOXA1 MCF7GSE15244 173515879 173516453 574 0
FOXA1 MCF7GSE15244 173518145 173519223 1078 0
Fos K562GSE19551 173330216 173331405 1189 0
Fos K562GSE19551 173507413 173508131 718 0
FoxA1 MCF7MACSdata 173297671 173297899 228 0
FoxA1 MCF7MACSdata 173404458 173404714 256 0
FoxA1 MCF7MACSdata 173498644 173498928 284 0
FoxA1 MCF7MACSdata 173598283 173598537 254 0
H3ac HepG2E 173241416 173242888 1472 0
H3ac HepG2E 173244850 173245284 434 0
Myc K562GSE19551 173330417 173331171 754 0
Nanog ESGSE20650 173501373 173501802 429 0
Nanog hESGSE18292 173501500 173501960 460 0
P300 T30-glioblastomaGSE21026 173329737 173331642 1905 0
P300 T30-glioblastomaGSE21026 173369477 173370617 1140 0
RARA MCF7GSE15244 173265833 173266118 285 0
RARA MCF7GSE15244 173330152 173331313 1161 0
RARA MCF7GSE15244 173335789 173336732 943 0
RARA MCF7GSE15244 173338150 173338942 792 0
RARA MCF7GSE15244 173340632 173341999 1367 0
RARA MCF7GSE15244 173342672 173343211 539 0
RARA MCF7GSE15244 173355584 173356090 506 0
RARA MCF7GSE15244 173356818 173357592 774 0
RARA MCF7GSE15244 173369500 173370278 778 0
RARA MCF7GSE15244 173380391 173381232 841 0
RARA MCF7GSE15244 173419296 173419905 609 0
RARA MCF7GSE15244 173507116 173508365 1249 0
RARA MCF7GSE15244 173518145 173519079 934 0
RARG MCF7GSE15244 173330152 173331313 1161 0
RARG MCF7GSE15244 173340884 173341889 1005 0
RARG MCF7GSE15244 173342672 173343211 539 0
RARG MCF7GSE15244 173355058 173355982 924 0
RARG MCF7GSE15244 173356921 173357592 671 0
RARG MCF7GSE15244 173369500 173370203 703 0
RARG MCF7GSE15244 173380391 173381271 880 0
RARG MCF7GSE15244 173507222 173508292 1070 0
RARG MCF7GSE15244 173518145 173519223 1078 0
Rb SenescentGSE19898 173241196 173241533 337 0
TFAP2C MCF7GSE21234 173330335 173330892 557 0
TFAP2C MCF7GSE21234 173342680 173343245 565 0
hScc1 BcellGSE12603 173294546 173294687 141 0
hScc1 BcellGSE12603 173308069 173308384 315 0
hScc1 BcellGSE12603 173530801 173531027 226 0
hScc1 CdLSGSE12603 173532817 173533524 707 0
hScc1 CdLSGSE12603 173541706 173542333 627 0
hScc1 G2GSE9613 173340925 173341416 491 0
hScc1 G2GSE9613 173540402 173540725 323 0
p130 SenescentGSE19898 173241320 173241536 216 0
p130 shRbQuiescentGSE19898 173282697 173283420 723 0
p63 keratinocytesGSE17611 173356492 173357463 971 0
p63 keratinocytesGSE17611 173535063 173535866 803 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-143 hsa-mir-143 5 19472311
hsa-miR-143* hsa-mir-143 5 19472311
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1041 Unknown pSILAC miR-16 FNDC3B down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000075420 n_a n_a n_a "epithelium, squamous cell, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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