AutismKB 2.0

Annotation Detail for KLC2


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Basic Information Top
Gene Symbol:KLC2 ( FLJ12387 )
Gene Full Name: kinesin light chain 2
Band: 11q13.2
Quick LinksEntrez ID:64837; OMIM: 611729; Uniprot ID:KLC2_HUMAN; ENSEMBL ID: ENSG00000174996; HGNC ID: 20716
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
445Phosphoserine.
507Phosphoserine.
508Phosphoserine.
582Phosphoserine.
589Phosphoserine.
610Phosphoserine.
Location(AA) Modifications Resource
445Phosphoserine.Swiss-Prot 53.0
507Phosphoserine.Swiss-Prot 53.0
507PhosphoserinePhospho.ELM 6.0
508Phosphoserine.Swiss-Prot 53.0
508PhosphoserinePhospho.ELM 6.0
582Phosphoserine.Swiss-Prot 53.0
582PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
13Phosphoserine(ATM)HMM predict
13Phosphoserine(CK2)HMM predict
13Phosphoserine(CK1)HMM predict
175Phosphoserine(ATM)HMM predict
175Phosphoserine(IKK)HMM predict
179Phosphoserine(CDK)HMM predict
179Phosphoserine(CDC2)HMM predict
179O-linkedHMM predict
256Phosphotyrosine(Syk)HMM predict
428Phosphoserine(PKA)HMM predict
428Phosphoserine(PKG)HMM predict
434SulfotyrosineHMM predict
449N-linkedHMM predict
587N-linkedHMM predict
604O-linkedHMM predict
608Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022822
  • Location:chr11 65781823-65791905
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 65780779 65782620 1841 124
Gata1 K562GSE18868 65780982 65781727 745 469
TFAP2C MCF7GSE21234 65781132 65781826 694 345
hScc1 BcellGSE12603 65777765 65777990 225 3946
hScc1 BcellGSE12603 65781450 65781807 357 195
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 65782341 65782591 250 0
CTCF CD4SISSRdata 65782341 65782591 250 0
NRSF pAbJurkat 65781521 65782680 1159 0
NRSF pAbJurkat 65788499 65789440 941 0
NRSF pAbJurkat 65790786 65791517 731 0
TFAP2C MCF7GSE21234 65781898 65782592 694 0
hScc1 BcellGSE12603 65782237 65782900 663 0
hScc1 CdLSGSE12603 65781450 65782680 1230 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4736 mRNA KLC2 chr11 65781823 65791906 231 EST chr11 65783621 65786049Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018