AutismKB 2.0

Annotation Detail for ST8SIA1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ST8SIA1 ( GD3S,SIAT8,SIAT8A,ST8SiaI )
Gene Full Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Band: 12p12.1
Quick LinksEntrez ID:6489; OMIM: 601123; Uniprot ID:SIA8A_HUMAN; ENSEMBL ID: ENSG00000111728; HGNC ID: 10869
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
71N-linked (GlcNAc...) (Potential).
119N-linked (GlcNAc...) (Potential).
214N-linked (GlcNAc...) (Potential).
245N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
71N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
119N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
214N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
245N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
11Phosphothreonine(PKA)HMM predict
11Phosphothreonine(PKC)HMM predict
71N-linkedHMM predict
119N-linkedHMM predict
180Phosphoserine(CK1)HMM predict
217SulfotyrosineHMM predict
312Phosphotyrosine(Syk)HMM predict
312SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003034
  • Location:chr12 22245201-22378914
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 22379684 22380299 615 1077
hScc1 BcellGSE12603 22378747 22379115 368 17
hScc1 BcellGSE12603 22379647 22380151 504 985
hScc1 CdLSGSE12603 22379511 22380299 788 991
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22365250 22365510 260 0
CTCF G2GSE9613 22378052 22378425 373 0
CTCF G2GSE9613 22378667 22379044 377 0
FOXA1 DLD1GSE12801 22294670 22295928 1258 0
GATA3 MCF7GSE15244 22327963 22328530 567 0
H3K27me3 colorectalcancer 22376272 22376630 358 0
H3K27me3 colorectalcancer 22377017 22378165 1148 0
Oct1 H2O2-HelaGSE14283 22296420 22296472 52 0
Oct1 HelaGSE14283 22263491 22263523 32 0
Oct1 HelaGSE14283 22296425 22296472 47 0
Oct1 HelaGSE14283 22315380 22315463 83 0
P300 T30-glioblastomaGSE21026 22356084 22357210 1126 0
RARG MCF7GSE15244 22319781 22320640 859 0
TFAP2C MCF7GSE21234 22319903 22320487 584 0
TFAP2C MCF7GSE21234 22357677 22358170 493 0
hScc1 BcellGSE12603 22378165 22378394 229 0
hScc1 CdLSGSE12603 22378706 22379071 365 0
hScc1 G2GSE9613 22378052 22378394 342 0
p63 keratinocytesGSE17611 22250020 22251067 1047 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018