AutismKB 2.0

Annotation Detail for SIPA1


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Basic Information Top
Gene Symbol:SIPA1 ( MGC102688,MGC17037,SPA1 )
Gene Full Name: signal-induced proliferation-associated 1
Band: 11q13.1
Quick LinksEntrez ID:6494; OMIM: 602180; Uniprot ID:SIPA1_HUMAN; ENSEMBL ID: ENSG00000213445; HGNC ID: 10885
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
53Phosphoserine.
55Phosphoserine.
64Phosphothreonine.
67Phosphoserine.
74Phosphoserine.
839Phosphoserine.
Location(AA) Modifications Resource
55PhosphoserinePhospho.ELM 6.0
67PhosphoserinePhospho.ELM 6.0
74Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
10Phosphoserine(CDC2)HMM predict
37Phosphothreonine(MAPK)HMM predict
55Phosphoserine(CK2)HMM predict
64Phosphothreonine(CDK)HMM predict
67PhosphoserineHMM predict
67Phosphoserine(CDC2)HMM predict
67Phosphoserine(MAPK)HMM predict
139Phosphoserine(IKK)HMM predict
143Phosphoserine(CK1)HMM predict
182Phosphoserine(ATM)HMM predict
182Phosphoserine(MAPK)HMM predict
182Phosphoserine(CDC2)HMM predict
182O-linkedHMM predict
202N-linkedHMM predict
291PhosphoserineHMM predict
291Phosphoserine(CDC2)HMM predict
314Phosphoserine(CDC2)HMM predict
346PhosphoserineHMM predict
351Phosphotyrosine(Syk)HMM predict
390O-linkedHMM predict
468Phosphothreonine(MAPK)HMM predict
473Phosphotyrosine(Jak)HMM predict
478O-linkedHMM predict
483Phosphothreonine(PKA)HMM predict
545O-linkedHMM predict
547O-linkedHMM predict
738Phosphoserine(MAPK)HMM predict
817Phosphoserine(ATM)HMM predict
817Phosphoserine(CDC2)HMM predict
817Phosphoserine(CDK)HMM predict
834Phosphoserine(ATM)HMM predict
839Phosphoserine(CDC2)HMM predict
839Phosphoserine(ATM)HMM predict
839Phosphoserine(MAPK)HMM predict
843Phosphoserine(CK1)HMM predict
845Phosphoserine(ATM)HMM predict
853N-linkedHMM predict
867O-linkedHMM predict
870O-linkedHMM predict
884Phosphoserine(CDC2)HMM predict
884Phosphoserine(IKK)HMM predict
884Phosphoserine(CDK)HMM predict
901Phosphoserine(PKA)HMM predict
908Phosphoserine(PKA)HMM predict
947Phosphoserine(CK1)HMM predict
962Phosphothreonine(CDK)HMM predict
962O-linkedHMM predict
1020Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006747
  • Location:chr11 65162170-65174964
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 65159357 65160256 899 2364
Oct1 H2O2-HelaGSE14283 65161424 65161451 27 733
Oct1 H2O2-HelaGSE14283 65161607 65161634 27 550
Rb GrowingGSE19898 65154166 65154345 179 7915
hScc1 BcellGSE12603 65149711 65150909 1198 11861
hScc1 BcellGSE12603 65161906 65162378 472 29
hScc1 CdLSGSE12603 65149985 65150627 642 11865
hScc1 CdLSGSE12603 65155729 65155954 225 6329
p130 QuiescentGSE19898 65161854 65162090 236 199
p130 SenescentGSE19898 65161854 65162411 557 38
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 65162005 65162636 631 0
Rb QuiescentGSE19898 65161964 65162384 420 0
Rb SenescentGSE19898 65161891 65162555 664 0
TAF HelaGSE8489 65162342 65162927 585 0
hScc1 G2GSE9613 65161906 65163072 1166 0
p130 QuiescentGSE19898 65162189 65162491 302 0
p130 shRbSenescentGSE19898 65161845 65162788 943 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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