AutismKB 2.0

Annotation Detail for SLAMF1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLAMF1 ( CD150,CDw150,SLAM )
Gene Full Name: signaling lymphocytic activation molecule family member 1
Band: 1q23.3
Quick LinksEntrez ID:6504; OMIM: 603492; Uniprot ID:SLAF1_HUMAN; ENSEMBL ID: ENSG00000117090; HGNC ID: 10903
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
53N-linked (GlcNAc...) (Potential).
57N-linked (GlcNAc...) (Potential).
102N-linked (GlcNAc...) (Potential).
125N-linked (GlcNAc...) (Potential).
150N-linked (GlcNAc...) (Potential).
155N-linked (GlcNAc...) (Potential).
189N-linked (GlcNAc...) (Potential).
217N-linked (GlcNAc...) (Potential).
281Phosphotyrosine.
286SH2-binding (Potential).
312SH2-binding (Potential).
332SH2-binding (Potential).
Location(AA) Modifications Resource
53N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
57N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
102N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
125N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
150N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
155N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
189N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
217N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
281Phosphotyrosine (Fyn)Phospho.ELM 6.0
307Phosphotyrosine (Fyn;Lck)Phospho.ELM 6.0
327Phosphotyrosine (Fyn;Lyn)Phospho.ELM 6.0
Location(AA) Modification Resource
69Phosphoserine(PKG)HMM predict
150N-linkedHMM predict
155N-linkedHMM predict
189N-linkedHMM predict
207Phosphotyrosine(EGFR)HMM predict
217N-linkedHMM predict
218N-linkedHMM predict
271Phosphothreonine(PKC)HMM predict
272Phosphothreonine(PKC)HMM predict
317Phosphoserine(IKK)HMM predict
325O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003037
  • Location:chr1 158846513-158883492
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 158888499 158889025 526 5270
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 158843458 158843863 405 2853
CTCF CD4SISSRdata 158843458 158843863 405 2853
Oct1 HelaGSE14283 158835511 158835550 39 10983
hScc1 BcellGSE12603 158843393 158843953 560 2841
hScc1 CdLSGSE12603 158843322 158843953 631 2876
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 158855117 158855494 377 0
CTCF CD4SISSRdata 158855117 158855494 377 0
CTCF HelaGSE12889 158855142 158855508 366 0
ER E2-MCF7GSE14664 158854927 158854976 49 0
GABP k562GSE8489 158878986 158879314 328 0
Myc hESGSE17917 158865435 158865695 260 0
Oct1 HelaGSE14283 158854938 158854973 35 0
Pol2 GM12878GSE19551 158866773 158872039 5266 0
SRF HepG2GSE8489 158865155 158865931 776 0
hScc1 BcellGSE12603 158882139 158882461 322 0
hScc1 CdLSGSE12603 158854896 158855800 904 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125b hsa-mir-125b-1 11 21118986
hsa-miR-125b hsa-mir-125b-2 21 21118986
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018