AutismKB 2.0

Annotation Detail for SLC1A3


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Basic Information Top
Gene Symbol:SLC1A3 ( EA6,EAAT1,FLJ25094,GLAST,GLAST1 )
Gene Full Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Band: 5p13.2
Quick LinksEntrez ID:6507; OMIM: 600111; Uniprot ID:EAA1_HUMAN; ENSEMBL ID: ENSG00000079215; HGNC ID: 10941
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
512Phosphoserine.
Location(AA) Modifications Resource
512Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
26Phosphothreonine(PKC)HMM predict
26Phosphothreonine(PKA)HMM predict
35N-linkedHMM predict
206N-linkedHMM predict
237Phosphoserine(IKK)HMM predict
363O-linkedHMM predict
364O-linkedHMM predict
364O-linkedHMM predict
365O-linkedHMM predict
368O-linkedHMM predict
434O-linkedHMM predict
437O-linkedHMM predict
530N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004172
  • Location:chr5 36642447-36724190
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 36631902 36631942 40 10526
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 36731963 36732215 252 7899
CTCF CD4SISSRdata 36731963 36732215 252 7899
CTCF G2GSE9613 36724325 36725364 1039 654
CTCF G2GSE9613 36725976 36726753 777 2174
CTCF G2GSE9613 36728716 36729329 613 4832
CTCF G2GSE9613 36731693 36732343 650 7828
CTCF G2GSE9613 36733083 36733833 750 9268
CTCF G2GSE9613 36740908 36741243 335 16885
Rb QuiescentGSE19898 36726264 36726423 159 2153
Rb QuiescentGSE19898 36732076 36732215 139 7955
Rb SenescentGSE19898 36726227 36726464 237 2155
hScc1 BcellGSE12603 36728750 36729329 579 4849
hScc1 BcellGSE12603 36731979 36732267 288 7933
hScc1 CdLSGSE12603 36726120 36726786 666 2263
hScc1 CdLSGSE12603 36728785 36729329 544 4867
hScc1 G2GSE9613 36726012 36726786 774 2209
hScc1 G2GSE9613 36728606 36729329 723 4777
hScc1 G2GSE9613 36731657 36732412 755 7844
p130 SenescentGSE19898 36726081 36726421 340 2061
p130 SenescentGSE19898 36726534 36726698 164 2426
p130 shRbSenescentGSE19898 36726092 36726377 285 2044
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 36693824 36694212 388 0
CTCF G2GSE9613 36720054 36720405 351 0
FOXA1 MCF7GSE15244 36702883 36704289 1406 0
FoxA1 MCF7MACSdata 36702927 36703148 221 0
FoxA1 MCF7MACSdata 36703710 36703932 222 0
H3K27me3 colorectalcancer 36641937 36643478 1541 0
Oct1 H2O2-HelaGSE14283 36651599 36651639 40 0
Oct1 HelaGSE14283 36651591 36651637 46 0
Oct1 HelaGSE14283 36654278 36654305 27 0
P300 T0-glioblastomaGSE21026 36693128 36694117 989 0
P300 T30-glioblastomaGSE21026 36693205 36694121 916 0
PolII HeLaGSE12783 36641976 36644459 2483 0
RARA MCF7GSE15244 36702848 36704325 1477 0
STAT1 HeLaGSE12783 36700230 36705353 5123 0
TAF HelaGSE8489 36641769 36643539 1770 0
TAF HelaGSE8489 36656545 36656741 196 0
TFAP2C MCF7GSE21234 36671944 36672262 318 0
TFAP2C MCF7GSE21234 36702820 36703354 534 0
p130 SenescentGSE19898 36682002 36682289 287 0
p63 keratinocytesGSE17611 36665830 36667052 1222 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-124 hsa-mir-124-1 8 18942755
hsa-miR-124 hsa-mir-124-2 8 18942755
hsa-miR-124 hsa-mir-124-3 20 18942755
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
20851 mRNA SLC1A3 chr5 36642447 36724197 22125 EST chr5 36702072 36761032 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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