AutismKB 2.0

Annotation Detail for PCDH15


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Basic Information Top
Gene Symbol:PCDH15 ( CDHR15,DFNB23,DKFZp667A1711,USH1F )
Gene Full Name: protocadherin-related 15
Band: 10q21.1
Quick LinksEntrez ID:65217; OMIM: 605514; Uniprot ID:PCD15_HUMAN; ENSEMBL ID: ENSG00000150275; HGNC ID: 14674
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
52N-linked (GlcNAc...) (Potential).
97N-linked (GlcNAc...) (Potential).
201N-linked (GlcNAc...) (Potential).
419N-linked (GlcNAc...) (Potential).
559N-linked (GlcNAc...) (Potential).
662N-linked (GlcNAc...) (Potential).
724N-linked (GlcNAc...) (Potential).
768N-linked (GlcNAc...) (Potential).
821N-linked (GlcNAc...) (Potential).
851N-linked (GlcNAc...) (Potential).
1064N-linked (GlcNAc...) (Potential).
1084N-linked (GlcNAc...) (Potential).
1175N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
52N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
97N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
201N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
419N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
559N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
662N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
724N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
768N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
821N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
851N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1064N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1084N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1175N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
52N-linkedHMM predict
63O-linkedHMM predict
65O-linkedHMM predict
97N-linkedHMM predict
153Phosphotyrosine(EGFR)HMM predict
155Phosphothreonine(PKC)HMM predict
201N-linkedHMM predict
247Phosphothreonine(PKA)HMM predict
249O-linkedHMM predict
291Phosphothreonine(CDK)HMM predict
291Phosphothreonine(MAPK)HMM predict
334Phosphotyrosine(EGFR)HMM predict
390N-linkedHMM predict
396Phosphothreonine(PKC)HMM predict
403Phosphotyrosine(INSR)HMM predict
417O-linkedHMM predict
419N-linkedHMM predict
422Phosphoserine(CDC2)HMM predict
455O-linkedHMM predict
476Phosphothreonine(PKC)HMM predict
559N-linkedHMM predict
597Phosphoserine(PKG)HMM predict
597Phosphoserine(IKK)HMM predict
610N-linkedHMM predict
662N-linkedHMM predict
726Phosphoserine(PKG)HMM predict
770Phosphoserine(PKA)HMM predict
821N-linkedHMM predict
902SulfotyrosineHMM predict
922Phosphotyrosine(Syk)HMM predict
947O-linkedHMM predict
1017Phosphoserine(CK1)HMM predict
1021Phosphothreonine(PKC)HMM predict
1040Phosphotyrosine(Syk)HMM predict
1046O-linkedHMM predict
1053Phosphothreonine(PKA)HMM predict
1084N-linkedHMM predict
1176Phosphotyrosine(INSR)HMM predict
1176Phosphotyrosine(SRC)HMM predict
1303Phosphotyrosine(INSR)HMM predict
1344Phosphotyrosine(Syk)HMM predict
1372Phosphotyrosine(INSR)HMM predict
1387S-palmitoylHMM predict
1388S-palmitoylHMM predict
1469N-linkedHMM predict
1470N-linkedHMM predict
1532N-linkedHMM predict
1534Phosphoserine(ATM)HMM predict
1543Phosphoserine(ATM)HMM predict
1632N-linkedHMM predict
1634Phosphothreonine(CK2)HMM predict
1655Phosphoserine(IKK)HMM predict
1657Phosphoserine(CK2)HMM predict
1661Phosphoserine(IKK)HMM predict
1701PhosphoserineHMM predict
1701Phosphoserine(CDK)HMM predict
1701Phosphoserine(CDC2)HMM predict
1717Phosphothreonine(PKA)HMM predict
1739N-linkedHMM predict
1743O-linkedHMM predict
1754O-linkedHMM predict
1754O-linkedHMM predict
1757O-linkedHMM predict
1775O-linkedHMM predict
1785O-linkedHMM predict
1785Phosphoserine(IKK)HMM predict
1799Phosphoserine(CK2)HMM predict
1799O-linkedHMM predict
1801Phosphoserine(IKK)HMM predict
1802O-linkedHMM predict
1803Phosphoserine(ATM)HMM predict
1803O-linkedHMM predict
1803Phosphoserine(IKK)HMM predict
1807Phosphothreonine(MAPK)HMM predict
1807Phosphothreonine(CDK)HMM predict
1816O-linkedHMM predict
1824O-linkedHMM predict
1832O-linkedHMM predict
1895Phosphoserine(IKK)HMM predict
1911N-linkedHMM predict
1929Phosphothreonine(CK2)HMM predict
1950Phosphoserine(IKK)HMM predict
1950Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033056
  • Location:chr10 55250865-56231056
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 56236275 56236303 28 5233
Oct1 HelaGSE14283 56236275 56236304 29 5233
Oct1 HelaGSE14283 56241501 56241538 37 10463
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 56203449 56203817 368 0
ER E2-MCF7GSE14664 55292464 55292500 36 0
ER E2-MCF7GSE14664 56076007 56076098 91 0
ER E2-MCF7GSE14664 56168517 56168549 32 0
ER E2-MCF7GSE14664 56169939 56169974 35 0
ER Fulvestrant-MCF7GSE14664 55292463 55292501 38 0
ER Fulvestrant-MCF7GSE14664 55883378 55883413 35 0
ER Fulvestrant-MCF7GSE14664 55903716 55903768 52 0
FoxA1 MCF7MACSdata 55316474 55316684 210 0
GABP k562GSE8489 55620970 55621369 399 0
GABP k562GSE8489 55923060 55923308 248 0
Nanog ESGSE20650 55840507 55840943 436 0
Nanog ESGSE20650 56037803 56038213 410 0
Nanog hESGSE18292 55596208 55596409 201 0
Nanog hESGSE18292 55767989 55768598 609 0
Oct1 H2O2-HelaGSE14283 55262500 55262528 28 0
Oct1 H2O2-HelaGSE14283 55292463 55292497 34 0
Oct1 H2O2-HelaGSE14283 55725941 55725974 33 0
Oct1 H2O2-HelaGSE14283 55761653 55761682 29 0
Oct1 H2O2-HelaGSE14283 55767475 55767505 30 0
Oct1 H2O2-HelaGSE14283 55821028 55821065 37 0
Oct1 H2O2-HelaGSE14283 55845698 55845739 41 0
Oct1 H2O2-HelaGSE14283 55903728 55903757 29 0
Oct1 H2O2-HelaGSE14283 55911946 55911976 30 0
Oct1 H2O2-HelaGSE14283 55938776 55938841 65 0
Oct1 H2O2-HelaGSE14283 55972526 55972554 28 0
Oct1 H2O2-HelaGSE14283 55982323 55982358 35 0
Oct1 H2O2-HelaGSE14283 56018620 56018648 28 0
Oct1 H2O2-HelaGSE14283 56058793 56058832 39 0
Oct1 H2O2-HelaGSE14283 56082481 56082523 42 0
Oct1 H2O2-HelaGSE14283 56114516 56114543 27 0
Oct1 H2O2-HelaGSE14283 56162221 56162260 39 0
Oct1 HelaGSE14283 55292463 55292498 35 0
Oct1 HelaGSE14283 55411399 55411432 33 0
Oct1 HelaGSE14283 55484436 55484470 34 0
Oct1 HelaGSE14283 55700854 55700884 30 0
Oct1 HelaGSE14283 55725942 55725974 32 0
Oct1 HelaGSE14283 55761652 55761682 30 0
Oct1 HelaGSE14283 55761754 55761782 28 0
Oct1 HelaGSE14283 55767475 55767505 30 0
Oct1 HelaGSE14283 55778591 55778670 79 0
Oct1 HelaGSE14283 55821029 55821066 37 0
Oct1 HelaGSE14283 55845693 55845738 45 0
Oct1 HelaGSE14283 55883371 55883407 36 0
Oct1 HelaGSE14283 55938776 55938826 50 0
Oct1 HelaGSE14283 55982324 55982357 33 0
Oct1 HelaGSE14283 55984284 55984314 30 0
Oct1 HelaGSE14283 56018615 56018659 44 0
Oct1 HelaGSE14283 56058795 56058833 38 0
Oct1 HelaGSE14283 56082479 56082523 44 0
Oct1 HelaGSE14283 56126878 56126945 67 0
Oct1 HelaGSE14283 56131811 56131845 34 0
Oct1 HelaGSE14283 56162225 56162260 35 0
Oct1 HelaGSE14283 56185066 56185096 30 0
Rb shRbSenescenceGSE19898 56189444 56189690 246 0
TAF k562GSE8489 55330282 55331230 948 0
TAF k562GSE8489 56226559 56227247 688 0
hScc1 BcellGSE12603 55692056 55692376 320 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3180 mRNA chr10 55915995 56085817 169822 mRNA PCDH15 chr10 55250865 56231057 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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