AutismKB 2.0

Annotation Detail for SLC5A5


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Basic Information Top
Gene Symbol:SLC5A5 ( NIS,TDH1 )
Gene Full Name: solute carrier family 5 (sodium iodide symporter), member 5
Band: 19p13.11
Quick LinksEntrez ID:6528; OMIM: 601843; Uniprot ID:SC5A5_HUMAN; ENSEMBL ID: ENSG00000105641; HGNC ID: 11040
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
489N-linked (GlcNAc...) (Potential).
502N-linked (GlcNAc...) (Potential).
556Phosphoserine; by PKA (Potential).
Location(AA) Modifications Resource
489N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
502N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
556Phosphoserine (by PKA) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphothreonine(PKC)HMM predict
120SulfotyrosineHMM predict
120PhosphotyrosineHMM predict
225N-linkedHMM predict
230N-linkedHMM predict
269Phosphotyrosine(Jak)HMM predict
319Phosphoserine(PKG)HMM predict
324Phosphotyrosine(Syk)HMM predict
351O-linkedHMM predict
353Phosphoserine(IKK)HMM predict
354O-linkedHMM predict
358O-linkedHMM predict
358Phosphoserine(IKK)HMM predict
400O-linkedHMM predict
502N-linkedHMM predict
505O-linkedHMM predict
636ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000453
  • Location:chr19 17843781-17865896
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 17841990 17842275 285 1649
Nanog hESGSE18292 17841232 17841426 194 2453
hScc1 BcellGSE12603 17841990 17842275 285 1649
hScc1 CdLSGSE12603 17841990 17842275 285 1649
hScc1 G2GSE9613 17841990 17842275 285 1649
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 17874695 17874782 87 8842
Oct4 hESGSE17917 17881080 17881562 482 15425
p63 keratinocytesGSE17611 17874357 17875036 679 8800
p63 keratinocytesGSE17611 17880892 17881673 781 15386
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 17849322 17850050 728 0
HIF1 HypoHepG2 17847693 17847937 244 0
NRSF JurkatGSE13047 17861203 17862059 856 0
NRSF JurkatGSE13047 17862347 17862985 638 0
NRSF mAbJurkat 17859869 17860372 503 0
NRSF mAbJurkat 17861450 17861844 394 0
NRSF mAbJurkat 17862561 17862983 422 0
NRSF mAbJurkat 17863603 17863794 191 0
NRSF mAbJurkat 17864491 17864745 254 0
NRSF mAbJurkat 17865221 17865911 690 0
NRSF-mono JurkatQuESTdata 17861202 17862040 838 0
NRSF-mono JurkatQuESTdata 17862414 17862978 564 0
NRSF-poly JurkatQuESTdata 17861293 17862037 744 0
NRSF-poly JurkatQuESTdata 17862347 17863166 819 0
hScc1 BcellGSE12603 17846049 17846285 236 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018