AutismKB 2.0

Annotation Detail for SLC8A3


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Basic Information Top
Gene Symbol:SLC8A3 ( NCX3 )
Gene Full Name: solute carrier family 8 (sodium/calcium exchanger), member 3
Band: 14q24.2
Quick LinksEntrez ID:6547; OMIM: 607991; Uniprot ID:NAC3_HUMAN; ENSEMBL ID: ENSG00000100678; HGNC ID: 11070
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
45N-linked (GlcNAc...) (Potential).
823N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
45N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
823N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
45N-linkedHMM predict
49Phosphoserine(ATM)HMM predict
113Phosphothreonine(PKC)HMM predict
130N-linkedHMM predict
135N-linkedHMM predict
244S-palmitoylHMM predict
267Phosphothreonine(PKC)HMM predict
384Phosphoserine(CK1)HMM predict
417Phosphothreonine(PKC)HMM predict
433SulfotyrosineHMM predict
446SulfotyrosineHMM predict
584SulfotyrosineHMM predict
584Phosphotyrosine(EGFR)HMM predict
584Phosphotyrosine(SRC)HMM predict
608SulfotyrosineHMM predict
608Phosphotyrosine(INSR)HMM predict
608Phosphotyrosine(Syk)HMM predict
608Phosphotyrosine(EGFR)HMM predict
634Phosphoserine(MAPK)HMM predict
643Phosphothreonine(PKC)HMM predict
719Phosphoserine(CK2)HMM predict
719Phosphoserine(CK1)HMM predict
816Phosphotyrosine(Jak)HMM predict
816Phosphotyrosine(Syk)HMM predict
823N-linkedHMM predict
828N-linkedHMM predict
866O-linkedHMM predict
923TyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033262
  • Location:chr14 69580687-69725539
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 69725679 69726275 596 438
hScc1 CdLSGSE12603 69729370 69729580 210 3936
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 69623654 69623836 182 0
CTCF CD4SISSRdata 69623654 69623836 182 0
CTCF G2GSE9613 69724358 69724667 309 0
ER E2-MCF7GSE14664 69660927 69661015 88 0
ER Fulvestrant-MCF7GSE14664 69656673 69656707 34 0
Oct1 HelaGSE14283 69638732 69638763 31 0
Oct1 HelaGSE14283 69654084 69654131 47 0
Oct1 HelaGSE14283 69656677 69656711 34 0
Oct1 HelaGSE14283 69659253 69659281 28 0
RING1B hESGSE13084 69703138 69703640 502 0
hScc1 BcellGSE12603 69623292 69624098 806 0
hScc1 BcellGSE12603 69725059 69725819 760 0
hScc1 CdLSGSE12603 69623541 69624205 664 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018