AutismKB 2.0

Annotation Detail for SLC11A1


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Basic Information Top
Gene Symbol:SLC11A1 ( LSH,NRAMP,NRAMP1 )
Gene Full Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Band: 2q35
Quick LinksEntrez ID:6556; OMIM: 600266; Uniprot ID:NRAM1_HUMAN; ENSEMBL ID: ENSG00000018280; HGNC ID: 10907
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
324N-linked (GlcNAc...) (Potential).
338N-linked (GlcNAc...) (Potential).
412Phosphothreonine.
Location(AA) Modifications Resource
324N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
338N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
11Phosphoserine(PKG)HMM predict
15Phosphotyrosine(INSR)HMM predict
17Phosphoserine(IKK)HMM predict
19O-linkedHMM predict
20Phosphoserine(CDC2)HMM predict
20Phosphoserine(CDK)HMM predict
22O-linkedHMM predict
22O-linkedHMM predict
23Phosphoserine(CDC2)HMM predict
23Phosphoserine(MAPK)HMM predict
23Phosphoserine(IKK)HMM predict
23O-linkedHMM predict
25O-linkedHMM predict
26PhosphoserineHMM predict
26Phosphoserine(CDC2)HMM predict
26Phosphoserine(MAPK)HMM predict
26O-linkedHMM predict
233S-palmitoylHMM predict
258Phosphotyrosine(Jak)HMM predict
324N-linkedHMM predict
330Phosphotyrosine(INSR)HMM predict
338N-linkedHMM predict
375O-linkedHMM predict
376O-linkedHMM predict
519S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000578
  • Location:chr2 218954995-218969859
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
STAT1 HeLaGSE12782 218947849 218948954 1105 6594
STAT1 HeLaGSE12783 218947756 218948920 1164 6658
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 218970303 218970696 393 640
FOXA1 MCF7GSE15244 218969434 218970303 869 9
H3ac HepG2E 218969511 218970675 1164 234
TFAP2C MCF7GSE21234 218968621 218971222 2601 62
VDR GM10861-UnstimGSE22484 218968475 218973854 5379 1305
VDR GM10861-stimGSE22484 218968687 218973341 4654 1155
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 218968902 218969295 393 0
CTCF CD4SISSRdata 218968902 218969295 393 0
CTCF G2GSE9613 218959580 218959994 414 0
CTCF G2GSE9613 218960776 218961008 232 0
CTCF G2GSE9613 218964273 218964525 252 0
CTCF G2GSE9613 218965733 218966022 289 0
CTCF G2GSE9613 218966916 218968034 1118 0
CTCF G2GSE9613 218968734 218969174 440 0
Rb GrowingGSE19898 218968862 218969198 336 0
Rb GrowingGSE19898 218969208 218969444 236 0
Rb QuiescentGSE19898 218968905 218969236 331 0
Rb QuiescentGSE19898 218969634 218969871 237 0
Rb SenescentGSE19898 218968817 218969836 1019 0
hScc1 BcellGSE12603 218966916 218967125 209 0
hScc1 BcellGSE12603 218968734 218969174 440 0
hScc1 CdLSGSE12603 218968734 218969406 672 0
hScc1 G2GSE9613 218968734 218969247 513 0
p130 QuiescentGSE19898 218969228 218969583 355 0
p130 SenescentGSE19898 218969137 218969654 517 0
p130 shRbQuiescentGSE19898 218969256 218969642 386 0
p130 shRbSenescentGSE19898 218968821 218969281 460 0
p130 shRbSenescentGSE19898 218969325 218969479 154 0
p63 keratinocytesGSE17611 218956520 218957335 815 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-29a hsa-mir-29a 7 19959559
hsa-miR-29a* hsa-mir-29a 7 19959559
hsa-miR-29b hsa-mir-29b-1 7 19959559
hsa-miR-29b hsa-mir-29b-2 1 19959559
hsa-miR-29b-1* hsa-mir-29b-1 7 19959559
hsa-miR-29b-2* hsa-mir-29b-2 1 19959559
hsa-miR-29c hsa-mir-29c 1 19959559
hsa-miR-29c* hsa-mir-29c 1 19959559
hsa-miR-34a hsa-mir-34a 1 18823940
hsa-miR-34a* hsa-mir-34a 1 18823940
hsa-miR-7 hsa-mir-7-1 9 18823940
hsa-miR-7 hsa-mir-7-2 15 18823940
hsa-miR-7 hsa-mir-7-3 19 18823940
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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