Annotation Detail for SLC16A1

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Basic Information Top

Gene Symbol:	SLC16A1 ( FLJ36745,HHF7,MCT,MCT1,MGC44475 )
Gene Full Name:	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Band:	1p13.2
Quick Links	Entrez ID:6566; OMIM: 600682; Uniprot ID:MOT1_HUMAN; ENSEMBL ID: ENSG00000155380; HGNC ID: 10922
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
210	Phosphoserine (By similarity).
213	Phosphoserine.
461	Phosphoserine.
466	Phosphothreonine.
467	Phosphoserine.
483	Phosphoserine.
498	Phosphoserine.

Location(AA)	Modifications	Resource
210	Phosphoserine (By similarity).	Swiss-Prot 53.0
213	Phosphoserine.	Swiss-Prot 53.0
213	Phosphoserine	Phospho.ELM 6.0
461	Phosphoserine	Phospho.ELM 6.0
466	Phosphothreonine.	Swiss-Prot 53.0
466	Phosphothreonine	Phospho.ELM 6.0
467	Phosphoserine.	Swiss-Prot 53.0
467	Phosphoserine	Phospho.ELM 6.0
483	Phosphoserine (By similarity).	Swiss-Prot 53.0
498	Phosphoserine.	Swiss-Prot 53.0
498	Phosphoserine	Phospho.ELM 6.0

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	113301061	113302107	1046	1087
USF1	HepG2	E	113300784	113301786	1002	788
p130	Quiescent	GSE19898	113300519	113300825	306	175
p130	Senescent	GSE19898	113300535	113300939	404	240
p130	shRbQuiescent	GSE19898	113300237	113300922	685	82
p130	shRbSenescent	GSE19898	113300580	113300825	245	205
p130	shRbSenescent	GSE19898	113301539	113301756	217	1150

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Oct1	H2O2-Hela	GSE14283	113246806	113246840	34	9172
RARA	MCF7	GSE15244	113247737	113248059	322	8097

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	113268209	113268349	140
CTCF	G2	GSE9613	113299563	113300811	1248
H3K4me3	colorectal	cancer	113299152	113300024	872
H3ac	HepG2	E	113298193	113299925	1732
Nanog	hES	GSE18292	113255787	113256249	462
Oct1	H2O2-Hela	GSE14283	113278458	113278502	44
Oct1	H2O2-Hela	GSE14283	113289989	113290026	37
Oct1	Hela	GSE14283	113278459	113278501	42
Oct1	Hela	GSE14283	113289989	113290024	35
PHF8	HeLa	GSE20725	113299258	113301411	2153
Pol2	GM12878	GSE19551	113299919	113300811	892
RARA	MCF7	GSE15244	113298124	113298762	638
RNAII	Tamoxifen-MCF7	GSE14664	113289990	113290025	35
Rb	Quiescent	GSE19898	113294627	113294871	244
Rb	Quiescent	GSE19898	113300351	113300636	285
STAT1	HeLa	GSE12783	113279543	113280849	1306
TAF	k562	GSE8489	113297612	113299709	2097
hScc1	Bcell	GSE12603	113268133	113268422	289
hScc1	Bcell	GSE12603	113299419	113300688	1269
p130	Quiescent	GSE19898	113300198	113300421	223
p130	Senescent	GSE19898	113300254	113300396	142
p130	shRbSenescent	GSE19898	113299959	113300493	534

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193
hsa-miR-376a	hsa-mir-376a-1	0	17322061
hsa-miR-376a	hsa-mir-376a-2	0	17322061
hsa-miR-376a*	hsa-mir-376a-1	0	17322061
hsa-miR-376b	hsa-mir-376b	0	17322061
hsa-miR-376c	hsa-mir-376c	0	17322061

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
413	mRNA cleavage	TRUE	miR-124	SLC16A1	n_a	16549876
696	mRNA repression	TRUE	miR-376a-5p	SLC16A1	in vitro reporter gene assay (Luciferase)	17322061
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000155380		G1-to-S transition	n_a	n_a	n_a	n_a
ENSG00000155380		n_a	n_a	n_a	n_a	n_a

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018