Annotation Detail for SLC25A1

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Basic Information Top

Gene Symbol:	SLC25A1 ( CTP,SLC20A3 )
Gene Full Name:	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
Band:	22q11.21
Quick Links	Entrez ID:6576; OMIM: 190315; Uniprot ID:TXTP_HUMAN; ENSEMBL ID: ENSG00000100075; HGNC ID: 10979
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	MCF7	GSE19013	17540285	17541340	1055	2282
ETS1	Jurkat	GSE17954	17538707	17539540	833	3971
FOXA1	MCF7	GSE15244	17535539	17536302	763	7174
FoxA1	MCF7	MACSdata	17535818	17536164	346	7104
H3ac	HepG2	E	17537558	17538385	827	5123
H3ac	HepG2	E	17539602	17541222	1620	2683
NFkBII	GM10847	GSE19485	17538488	17539786	1298	3958
PHF8	293T	GSE20725	17538268	17539935	1667	3993
PHF8	HeLa	GSE20725	17538386	17539997	1611	3903
PHF8	Hs68minusFBS	GSE20725	17538554	17539520	966	4058
PHF8	Hs68plusFBS	GSE20725	17538371	17540025	1654	3897
RARG	MCF7	GSE15244	17540168	17540554	386	2734
TFAP2C	MCF7	GSE21234	17535532	17536194	662	7232
hScc1	Bcell	GSE12603	17538642	17539518	876	4015
p130	shRbSenescent	GSE19898	17538681	17539042	361	4233

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
PHF8	HeLa	GSE20725	17545107	17546809	1702
hScc1	Bcell	GSE12603	17545145	17545505	360
p130	Senescent	GSE19898	17544362	17544754	392

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
895	Unknown	pSILAC	let-7b	SLC25A1	down 50-25%	18668040
1198	Unknown	pSILAC	miR-1	SLC25A1	down 75-50%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000100075		n_a	n_a	n_a	"epithelium, leukocyte, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000100075		n_a	n_a	n_a	"epithelium, leukocyte, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018