AutismKB 2.0

Annotation Detail for SLC22A3


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Basic Information Top
Gene Symbol:SLC22A3 ( EMT,EMTH,OCT3 )
Gene Full Name: solute carrier family 22 (extraneuronal monoamine transporter), member 3
Band: 6q25.3
Quick LinksEntrez ID:6581; OMIM: 604842; Uniprot ID:S22A3_HUMAN; ENSEMBL ID: ENSG00000146477; HGNC ID: 10967
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
72N-linked (GlcNAc...) (Potential).
99N-linked (GlcNAc...) (Potential).
119N-linked (GlcNAc...) (Potential).
322N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
72N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
99N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
119N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
322N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
26S-palmitoylHMM predict
72N-linkedHMM predict
99N-linkedHMM predict
101O-linkedHMM predict
103O-linkedHMM predict
105O-linkedHMM predict
119N-linkedHMM predict
322N-linkedHMM predict
324Phosphoserine(CK1)HMM predict
344Phosphothreonine(CDK)HMM predict
351Phosphothreonine(PKA)HMM predict
541CysteineHMM predict
543S-farnesylHMM predict
544GlycineHMM predict
546AsparagineHMM predict
549Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021977
  • Location:chr6 160689414-160796002
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 160670185 160670550 365 19047
CTCF G2GSE9613 160688190 160690018 1828 311
hScc1 BcellGSE12603 160688393 160689175 782 631
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 160797039 160797367 328 1201
CTCF CD4SISSRdata 160797039 160797367 328 1201
CTCF HelaGSE12889 160796885 160797242 357 1061
CTCF JurkatGSE12889 160797061 160797300 239 1178
CTCF G2GSE9613 160796797 160797629 832 1211
STAT1 IFNSISSRdata 160796800 160797254 454 1025
hScc1 BcellGSE12603 160796567 160797340 773 951
hScc1 CdLSGSE12603 160796475 160797549 1074 1010
hScc1 G2GSE9613 160796442 160797629 1187 1033
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 160704179 160704593 414 0
CTCF G2GSE9613 160708705 160709458 753 0
CTCF G2GSE9613 160727661 160728160 499 0
CTCF G2GSE9613 160786154 160786387 233 0
CTCF G2GSE9613 160786869 160787287 418 0
Fos K562GSE19551 160772999 160773328 329 0
H3K27me3 colorectalcancer 160691611 160691829 218 0
H3ac HepG2E 160690126 160692004 1878 0
NRSF JurkatGSE13047 160791923 160792325 402 0
NRSF-mono JurkatQuESTdata 160791922 160792208 286 0
hScc1 BcellGSE12603 160689615 160689930 315 0
hScc1 BcellGSE12603 160704213 160704523 310 0
hScc1 BcellGSE12603 160761924 160762329 405 0
hScc1 BcellGSE12603 160786869 160787265 396 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-100 hsa-mir-100 11 21109969
hsa-miR-100* hsa-mir-100 11 21109969
hsa-miR-155 hsa-mir-155 21 21130073
hsa-miR-155* hsa-mir-155 21 21130073
hsa-miR-192 hsa-mir-192 11 18805502
hsa-miR-192* hsa-mir-192 11 18805502
hsa-miR-200c hsa-mir-200c 12 21109969
hsa-miR-200c* hsa-mir-200c 12 21109969
hsa-miR-204 hsa-mir-204 9 21109969
hsa-miR-206 hsa-mir-206 6 21109969
hsa-miR-223 hsa-mir-223 X 21109969
hsa-miR-223* hsa-mir-223 X 21109969
hsa-miR-302a hsa-mir-302a 4 18755840
hsa-miR-302a* hsa-mir-302a 4 18755840
hsa-miR-302b hsa-mir-302b 4 18755840
hsa-miR-302b* hsa-mir-302b 4 18755840
hsa-miR-302c hsa-mir-302c 4 18755840
hsa-miR-302c* hsa-mir-302c 4 18755840
hsa-miR-302d hsa-mir-302d 4 18755840
hsa-miR-302d* hsa-mir-302d 4 18755840
hsa-miR-302f hsa-mir-302f 0 18755840
hsa-miR-320d hsa-mir-320d-1 13 21130073
hsa-miR-320d hsa-mir-320d-2 X 21130073
hsa-miR-429 hsa-mir-429 1 21130073
hsa-miR-9 hsa-mir-9-1 1 21109969
hsa-miR-9 hsa-mir-9-2 5 21109969
hsa-miR-9 hsa-mir-9-3 15 21109969
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23396 mRNA SLC22A3 chr6 160739835 160846425 335 EST chr6 160844644 160844979Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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