AutismKB 2.0

Annotation Detail for SLIT3


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Basic Information Top
Gene Symbol:SLIT3 ( FLJ10764,MEGF5,SLIL2,SLIT1,Slit-3,slit2 )
Gene Full Name: slit homolog 3 (Drosophila)
Band: 5q34-q35.1
Quick LinksEntrez ID:6586; OMIM: 603745; Uniprot ID:SLIT3_HUMAN; ENSEMBL ID: ENSG00000184347; HGNC ID: 11087
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
72N-linked (GlcNAc...) (Potential).
192N-linked (GlcNAc...) (Potential).
563N-linked (GlcNAc...) (Potential).
622N-linked (GlcNAc...) (Potential).
784N-linked (GlcNAc...) (Potential).
792N-linked (GlcNAc...) (Potential).
797N-linked (GlcNAc...) (Potential).
928N-linked (GlcNAc...) (Potential).
1008N-linked (GlcNAc...) (Potential).
1025N-linked (GlcNAc...) (Potential).
1181N-linked (GlcNAc...) (Potential).
1247N-linked (GlcNAc...) (Potential).
1406N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
72N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
192N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
563N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
622N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
784N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
792N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
797N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
928N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1008N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1025N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1181N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1247N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1406N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
39O-linkedHMM predict
72N-linkedHMM predict
98Phosphoserine(CK2)HMM predict
261Phosphotyrosine(Jak)HMM predict
261Phosphotyrosine(INSR)HMM predict
268Phosphoserine(IKK)HMM predict
272Phosphoserine(IKK)HMM predict
282Phosphoserine(IKK)HMM predict
417Phosphothreonine(PKC)HMM predict
466Phosphoserine(CDC2)HMM predict
491Phosphotyrosine(Syk)HMM predict
497Phosphoserine(PKB)HMM predict
622N-linkedHMM predict
792N-linkedHMM predict
797N-linkedHMM predict
837Phosphoserine(CK1)HMM predict
848Phosphoserine(CK1)HMM predict
886Phosphoserine(IKK)HMM predict
886Phosphoserine(CDC2)HMM predict
923Phosphoserine(CDC2)HMM predict
928N-linkedHMM predict
1008N-linkedHMM predict
1025N-linkedHMM predict
1097O-linkedHMM predict
1121Phosphoserine(IKK)HMM predict
1168Phosphotyrosine(EGFR)HMM predict
1221O-linkedHMM predict
1222Phosphoserine(CDC2)HMM predict
1222O-linkedHMM predict
1225O-linkedHMM predict
1228Phosphotyrosine(SRC)HMM predict
1247N-linkedHMM predict
1251N-linkedHMM predict
1275Phosphoserine(MAPK)HMM predict
1338S-palmitoylHMM predict
1377S-palmitoylHMM predict
1406N-linkedHMM predict
1410N-linkedHMM predict
1482S-palmitoylHMM predict
1492Phosphoserine(CDK)HMM predict
1492Phosphoserine(PKC)HMM predict
1506Phosphoserine(CK2)HMM predict
1523SerineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003062
  • Location:chr5 168025859-168660553
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 168662173 168662386 213 1726
CTCF CD4SISSRdata 168662173 168662386 213 1726
CTCF JurkatGSE12889 168662192 168662390 198 1738
CTCF G2GSE9613 168659946 168661380 1434 110
CTCF G2GSE9613 168662022 168662568 546 1742
H3K27me3 colorectalcancer 168660808 168662393 1585 1047
hScc1 BcellGSE12603 168661983 168662393 410 1635
hScc1 CdLSGSE12603 168661983 168662430 447 1653
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 168006834 168006999 165 18943
Rb GrowingGSE19898 168011457 168011667 210 14298
p63 keratinocytesGSE17611 168005655 168007201 1546 19432
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 168353861 168354471 610 0
CBP T30-glioblastomaGSE21026 168071706 168072802 1096 0
CTCF CD4GSE12889 168039124 168039334 210 0
CTCF CD4GSE12889 168306898 168307087 189 0
CTCF CD4GSE12889 168347250 168347424 174 0
CTCF CD4SISSRdata 168039124 168039334 210 0
CTCF CD4SISSRdata 168306898 168307087 189 0
CTCF CD4SISSRdata 168347250 168347424 174 0
CTCF HelaGSE12889 168038996 168039368 372 0
CTCF HelaGSE12889 168107948 168108162 214 0
CTCF JurkatGSE12889 168107969 168108141 172 0
CTCF G2GSE9613 168029347 168030068 721 0
CTCF G2GSE9613 168030686 168031242 556 0
CTCF G2GSE9613 168039172 168039540 368 0
CTCF G2GSE9613 168040118 168040416 298 0
CTCF G2GSE9613 168041291 168041635 344 0
CTCF G2GSE9613 168043326 168043647 321 0
CTCF G2GSE9613 168046519 168046694 175 0
CTCF G2GSE9613 168058659 168058979 320 0
CTCF G2GSE9613 168061028 168061749 721 0
CTCF G2GSE9613 168062312 168062445 133 0
CTCF G2GSE9613 168071958 168072111 153 0
CTCF G2GSE9613 168095872 168096388 516 0
CTCF G2GSE9613 168107824 168108318 494 0
CTCF G2GSE9613 168110654 168110943 289 0
CTCF G2GSE9613 168112463 168112671 208 0
CTCF G2GSE9613 168120219 168120547 328 0
CTCF G2GSE9613 168122014 168122236 222 0
CTCF G2GSE9613 168125974 168126186 212 0
CTCF G2GSE9613 168127682 168127898 216 0
CTCF G2GSE9613 168132111 168132414 303 0
CTCF G2GSE9613 168138168 168138523 355 0
CTCF G2GSE9613 168142766 168143018 252 0
CTCF G2GSE9613 168151733 168151876 143 0
CTCF G2GSE9613 168156587 168156871 284 0
CTCF G2GSE9613 168165837 168166381 544 0
CTCF G2GSE9613 168189233 168189636 403 0
CTCF G2GSE9613 168204145 168204330 185 0
CTCF G2GSE9613 168236902 168237111 209 0
CTCF G2GSE9613 168256949 168257451 502 0
CTCF G2GSE9613 168306107 168306322 215 0
CTCF G2GSE9613 168306791 168307320 529 0
CTCF G2GSE9613 168321585 168321802 217 0
CTCF G2GSE9613 168347212 168347352 140 0
CTCF G2GSE9613 168349060 168349280 220 0
CTCF G2GSE9613 168350899 168351313 414 0
CTCF G2GSE9613 168352225 168352994 769 0
CTCF G2GSE9613 168359088 168359355 267 0
CTCF G2GSE9613 168476631 168476810 179 0
CTCF G2GSE9613 168578662 168579113 451 0
CTCF G2GSE9613 168585423 168585835 412 0
CTCF G2GSE9613 168625368 168625848 480 0
CTCF G2GSE9613 168628907 168629192 285 0
CTCF G2GSE9613 168630590 168630953 363 0
CTCF G2GSE9613 168632383 168632685 302 0
CTCF G2GSE9613 168646262 168646547 285 0
CTCF G2GSE9613 168649182 168649583 401 0
CTCF G2GSE9613 168657717 168658225 508 0
FOXA1 MCF7GSE15244 168429395 168430355 960 0
FOXA1 MCF7GSE15244 168499152 168499740 588 0
FOXA1 MCF7GSE15244 168578371 168579640 1269 0
FoxA1 MCF7MACSdata 168082449 168082594 145 0
FoxA1 MCF7MACSdata 168578429 168578933 504 0
Gata2 K562GSE18868 168173037 168173723 686 0
H3K27me3 colorectalcancer 168657959 168658263 304 0
H3K27me3 colorectalcancer 168658883 168659630 747 0
KLF4 hESGSE17917 168058242 168058397 155 0
Myc K562GSE19551 168173132 168173610 478 0
NRSF mAbJurkat 168086933 168087199 266 0
NRSF-poly JurkatQuESTdata 168455074 168455363 289 0
Nanog ESGSE20650 168582755 168583279 524 0
Nanog ESGSE20650 168638811 168639038 227 0
Nanog hESGSE18292 168066243 168066524 281 0
Nanog hESGSE18292 168187187 168187706 519 0
Nanog hESGSE18292 168234266 168234686 420 0
Nanog hESGSE18292 168460167 168460646 479 0
Nanog hESGSE18292 168524007 168524448 441 0
Nanog hESGSE18292 168582809 168583297 488 0
Oct4 ESGSE20650 168531077 168531469 392 0
Oct4 hESGSE21916 168638702 168639018 316 0
P300 T0-glioblastomaGSE21026 168459543 168460898 1355 0
P300 T30-glioblastomaGSE21026 168071727 168072854 1127 0
P300 T30-glioblastomaGSE21026 168459337 168460977 1640 0
RARA MCF7GSE15244 168429282 168430759 1477 0
RARA MCF7GSE15244 168458185 168460910 2725 0
RARG MCF7GSE15244 168429282 168430694 1412 0
Sox2 hESGSE18292 168187185 168187856 671 0
Sox2 hESGSE18292 168524220 168524451 231 0
Sox2 hESGSE18292 168582744 168583195 451 0
Stat6 IL-4-hr1GSE17850 168396929 168397397 468 0
TFAP2C MCF7GSE21234 168056676 168057211 535 0
TFAP2C MCF7GSE21234 168058313 168059225 912 0
TFAP2C MCF7GSE21234 168082227 168082676 449 0
TFAP2C MCF7GSE21234 168234150 168234701 551 0
TFAP2C MCF7GSE21234 168578424 168578869 445 0
hScc1 BcellGSE12603 168039172 168039540 368 0
hScc1 BcellGSE12603 168107959 168108283 324 0
hScc1 BcellGSE12603 168334617 168334956 339 0
hScc1 BcellGSE12603 168346913 168347557 644 0
hScc1 BcellGSE12603 168524271 168524464 193 0
hScc1 CdLSGSE12603 168039172 168039540 368 0
hScc1 CdLSGSE12603 168066044 168066652 608 0
hScc1 CdLSGSE12603 168107930 168108389 459 0
hScc1 CdLSGSE12603 168346913 168347606 693 0
hScc1 G2GSE9613 168039172 168039540 368 0
p130 SenescentGSE19898 168041217 168041426 209 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21808 mRNA chr5 168066149 168080467 195 mRNA SLIT3 chr5 168026036 168113556Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018