AutismKB 2.0

Annotation Detail for HLTF


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Basic Information Top
Gene Symbol:HLTF ( HIP116,HIP116A,HLTF1,RNF80,SMARCA3,SNF2L3,ZBU1 )
Gene Full Name: helicase-like transcription factor
Band: 3q24
Quick LinksEntrez ID:6596; OMIM: 603257; Uniprot ID:HLTF_HUMAN; ENSEMBL ID: ENSG00000071794; HGNC ID: 11099
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
390Phosphothreonine.
394Phosphotyrosine.
397Phosphoserine.
398Phosphoserine.
400Phosphoserine.
560DEGH box.
635Phosphoserine (By similarity).
736Phosphothreonine.
Location(AA) Modifications Resource
397Phosphoserine.Swiss-Prot 53.0
397PhosphoserinePhospho.ELM 6.0
398Phosphoserine.Swiss-Prot 53.0
398PhosphoserinePhospho.ELM 6.0
400Phosphoserine.Swiss-Prot 53.0
400PhosphoserinePhospho.ELM 6.0
635Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
13Phosphotyrosine(Jak)HMM predict
93Phosphotyrosine(Syk)HMM predict
194O-linkedHMM predict
195Phosphotyrosine(Abl)HMM predict
238Phosphothreonine(CDK)HMM predict
257Phosphoserine(CK1)HMM predict
344N-linkedHMM predict
345N-linkedHMM predict
358Phosphoserine(CK2)HMM predict
381Phosphoserine(CK1)HMM predict
390Phosphothreonine(PKA)HMM predict
400O-linkedHMM predict
400Phosphoserine(CK1)HMM predict
400PhosphoserineHMM predict
445O-linkedHMM predict
446O-linkedHMM predict
447O-linkedHMM predict
447Phosphoserine(IKK)HMM predict
450Phosphothreonine(PKC)HMM predict
469Phosphothreonine(CK2)HMM predict
538SulfotyrosineHMM predict
544PhosphoserineHMM predict
639N-linkedHMM predict
647Phosphothreonine(PKC)HMM predict
678Phosphotyrosine(Syk)HMM predict
688Phosphothreonine(PKC)HMM predict
717S-palmitoylHMM predict
734N-linkedHMM predict
736Phosphothreonine(MAPK)HMM predict
783S-palmitoylHMM predict
998AlanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_139048
  • Location:chr3 150230593-150287030
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
KLF4 hESGSE17917 150298192 150298513 321 11322
LIN9 G0GSE7516 150286747 150287330 583 8
Oct4 hESGSE17917 150298202 150298513 311 11327
Rb GrowingGSE19898 150286941 150287259 318 70
Rb QuiescentGSE19898 150286929 150287286 357 77
Rb SenescentGSE19898 150286771 150287338 567 24
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 150286039 150287330 1291 0
Fos K562GSE19551 150286158 150287466 1308 0
Gata1 K562GSE18868 150286055 150286807 752 0
Gata2 K562GSE18868 150286085 150286855 770 0
H3K4me3 colorectalcancer 150285992 150286854 862 0
Oct1 H2O2-HelaGSE14283 150231487 150231534 47 0
Oct1 HelaGSE14283 150231487 150231533 46 0
PHF8 293TGSE20725 150286308 150287454 1146 0
PHF8 HeLaGSE20725 150286527 150287437 910 0
RARG MCF7GSE15244 150285992 150287402 1410 0
p130 G0GSE7516 150286589 150287292 703 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018