AutismKB 2.0

Annotation Detail for ZBTB10


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZBTB10 ( FLJ12752,RINZF )
Gene Full Name: zinc finger and BTB domain containing 10
Band: 8q21.13
Quick LinksEntrez ID:65986; OMIM: NA; Uniprot ID:ZBT10_HUMAN; ENSEMBL ID: ENSG00000205189; HGNC ID: 30953
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
210Phosphoserine.
565Phosphoserine.
647Phosphoserine.
745Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
10Phosphothreonine(PKA)HMM predict
36O-linkedHMM predict
50O-linkedHMM predict
50O-linkedHMM predict
122Phosphothreonine(PKA)HMM predict
136N-linkedHMM predict
140MethylarginineHMM predict
145Phosphothreonine(PKC)HMM predict
181Phosphoserine(ATM)HMM predict
183Phosphoserine(CK2)HMM predict
183PhosphoserineHMM predict
184Phosphothreonine(CK2)HMM predict
203Phosphoserine(IKK)HMM predict
278Phosphothreonine(CDC2)HMM predict
330Phosphoserine(CK1)HMM predict
334Phosphotyrosine(Syk)HMM predict
404N-linkedHMM predict
405N-linkedHMM predict
483MethyllysineHMM predict
506N-linkedHMM predict
509N-linkedHMM predict
534N-linkedHMM predict
549N-linkedHMM predict
578N-linkedHMM predict
592N-linkedHMM predict
595N-linkedHMM predict
647Phosphoserine(ATM)HMM predict
712Phosphothreonine(PKC)HMM predict
731S-palmitoylHMM predict
736Phosphothreonine(PKC)HMM predict
754Phosphotyrosine(INSR)HMM predict
810Phosphotyrosine(EGFR)HMM predict
810Phosphotyrosine(INSR)HMM predict
810Phosphotyrosine(Syk)HMM predict
842S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_023929
  • Location:chr8 81561002-81595321
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 81560081 81560680 599 622
Fos K562GSE19551 81560009 81560655 646 671
FoxA1 MCF7MACSdata 81560095 81560471 376 720
Myc K562GSE19551 81560089 81561469 1380 224
NFkBII GM10847GSE19485 81557086 81558241 1155 3339
NFkBII GM12878GSE19485 81556930 81558395 1465 3340
NFkBII GM12892GSE19485 81557105 81558409 1304 3246
NFkBII GM18505GSE19485 81557057 81558214 1157 3367
NFkBII GM18526GSE19485 81557040 81558289 1249 3338
PHF8 293TGSE20725 81560280 81561564 1284 81
RARG MCF7GSE15244 81560242 81560637 395 563
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 81560572 81562075 1503 0
CTCF G2GSE9613 81564815 81565022 207 0
FOXA1 MCF7GSE15244 81562282 81562612 330 0
H3K4me3 colorectalcancer 81562387 81563427 1040 0
H3ac HepG2E 81562142 81564526 2384 0
Myc K562GSE19551 81580487 81580731 244 0
PHF8 HeLaGSE20725 81560866 81561965 1099 0
PHF8 Hs68minusFBSGSE20725 81560837 81561793 956 0
Rb SenescentGSE19898 81561977 81562400 423 0
TFAP2C MCF7GSE21234 81560901 81561268 367 0
hScc1 BcellGSE12603 81560572 81562351 1779 0
hScc1 BcellGSE12603 81564815 81565022 207 0
hScc1 CdLSGSE12603 81564704 81565022 318 0
p130 QuiescentGSE19898 81560945 81561240 295 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-27a hsa-mir-27a 19 21156786
hsa-miR-27a hsa-mir-27a 19 20666778
hsa-miR-27a hsa-mir-27a 19 20488920
hsa-miR-27a hsa-mir-27a 19 20382698
hsa-miR-27a hsa-mir-27a 19 19639204
hsa-miR-27a hsa-mir-27a 19 19582879
hsa-miR-27a hsa-mir-27a 19 18006846
hsa-miR-27a hsa-mir-27a 19 16452179
hsa-miR-27a* hsa-mir-27a 19 21156786
hsa-miR-27a* hsa-mir-27a 19 20666778
hsa-miR-27a* hsa-mir-27a 19 20488920
hsa-miR-27a* hsa-mir-27a 19 20382698
hsa-miR-27a* hsa-mir-27a 19 19639204
hsa-miR-27a* hsa-mir-27a 19 19582879
hsa-miR-27a* hsa-mir-27a 19 18006846
hsa-miR-27a* hsa-mir-27a 19 16452179
hsa-miR-27b hsa-mir-27b 9 16452179
hsa-miR-27b* hsa-mir-27b 9 16452179
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
576 mRNA cleavage TRUE miR-27a ZBTB10 Luciferase assay - mutant MRE 18006846
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000205189 n_a breast cancer up regulated n_a n_a
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018