AutismKB 2.0

Annotation Detail for SIGLEC1


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Basic Information Top
Gene Symbol:SIGLEC1 ( CD169,DKFZp667F058,FLJ00051,FLJ00055,FLJ00073,FLJ00411,FLJ32150,SIGLEC-1,SN,dJ1009E24.1 )
Gene Full Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Band: 20p13
Quick LinksEntrez ID:6614; OMIM: 600751; Uniprot ID:SN_HUMAN; ENSEMBL ID: ENSG00000088827; HGNC ID: 11127
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
159N-linked (GlcNAc...) (Potential).
265N-linked (GlcNAc...) (Potential).
339N-linked (GlcNAc...) (Potential).
499N-linked (GlcNAc...) (Potential).
697N-linked (GlcNAc...) (Potential).
726N-linked (GlcNAc...) (Potential).
730N-linked (GlcNAc...) (Potential).
741N-linked (GlcNAc...) (Potential).
886N-linked (GlcNAc...) (Potential).
1104N-linked (GlcNAc...) (Potential).
1138N-linked (GlcNAc...) (Potential).
1251N-linked (GlcNAc...) (Potential).
1462N-linked (GlcNAc...) (Potential).
1476N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
159N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
265N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
339N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
499N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
697N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
726N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
730N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
741N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
886N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1104N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1138N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1251N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1462N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1476N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
25Phosphoserine(CDC2)HMM predict
41S-palmitoylHMM predict
146Phosphoserine(CDC2)HMM predict
146Phosphoserine(MAPK)HMM predict
159N-linkedHMM predict
164Phosphotyrosine(Jak)HMM predict
246Phosphoserine(CDC2)HMM predict
265N-linkedHMM predict
313O-linkedHMM predict
331Phosphoserine(IKK)HMM predict
331Phosphoserine(CDC2)HMM predict
339N-linkedHMM predict
401Phosphoserine(ATM)HMM predict
414Phosphothreonine(CDK)HMM predict
489Phosphotyrosine(INSR)HMM predict
499N-linkedHMM predict
516Phosphoserine(MAPK)HMM predict
516Phosphoserine(CDC2)HMM predict
533O-linkedHMM predict
533Phosphoserine(IKK)HMM predict
536Phosphoserine(CDC2)HMM predict
536O-linkedHMM predict
582Phosphoserine(IKK)HMM predict
587O-linkedHMM predict
588Phosphoserine(MAPK)HMM predict
588Phosphoserine(CDC2)HMM predict
588Phosphoserine(CDK)HMM predict
649O-linkedHMM predict
656S-palmitoylHMM predict
687Phosphotyrosine(INSR)HMM predict
697N-linkedHMM predict
726N-linkedHMM predict
730N-linkedHMM predict
741N-linkedHMM predict
747N-linkedHMM predict
874Phosphotyrosine(Jak)HMM predict
874Phosphotyrosine(INSR)HMM predict
901Phosphoserine(CDC2)HMM predict
940Phosphoserine(IKK)HMM predict
944Phosphothreonine(PKC)HMM predict
969O-linkedHMM predict
970O-linkedHMM predict
971Phosphoserine(IKK)HMM predict
971O-linkedHMM predict
988Phosphothreonine(PKA)HMM predict
1065Phosphotyrosine(INSR)HMM predict
1104N-linkedHMM predict
1119SulfotyrosineHMM predict
1122PhosphotyrosineHMM predict
1138N-linkedHMM predict
1161O-linkedHMM predict
1215O-linkedHMM predict
1219Phosphoserine(IKK)HMM predict
1280O-linkedHMM predict
1292SulfotyrosineHMM predict
1332Phosphothreonine(PKC)HMM predict
1357Phosphoserine(PKA)HMM predict
1361Phosphoserine(PKB)HMM predict
1423Phosphotyrosine(Jak)HMM predict
1423Phosphotyrosine(INSR)HMM predict
1423Phosphotyrosine(EGFR)HMM predict
1476N-linkedHMM predict
1495Phosphothreonine(PKC)HMM predict
1576Phosphoserine(ATM)HMM predict
1611Phosphotyrosine(INSR)HMM predict
1621O-linkedHMM predict
1624O-linkedHMM predict
1626O-linkedHMM predict
1701O-linkedHMM predict
1702O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_023068
  • Location:chr20 3615618-3635774
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3639654 3639816 162 3961
CTCF CD4GSE12889 3644964 3645125 161 9270
CTCF CD4SISSRdata 3639654 3639816 162 3961
CTCF CD4SISSRdata 3644964 3645125 161 9270
CTCF HelaGSE12889 3644964 3645254 290 9335
CTCF G2GSE9613 3639090 3640125 1035 3833
hScc1 BcellGSE12603 3639259 3639887 628 3799
hScc1 BcellGSE12603 3644943 3645574 631 9484
hScc1 CdLSGSE12603 3639226 3640087 861 3882
hScc1 CdLSGSE12603 3644943 3645536 593 9465
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3618650 3618899 249 0
CTCF G2GSE9613 3621257 3621738 481 0
CTCF G2GSE9613 3624960 3625630 670 0
Fos K562GSE19551 3616280 3616829 549 0
TFAP2C MCF7GSE21234 3626208 3626787 579 0
hScc1 BcellGSE12603 3625458 3626120 662 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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