AutismKB 2.0

Annotation Detail for SNCB


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Basic Information Top
Gene Symbol:SNCB ( - )
Gene Full Name: synuclein, beta
Band: 5q35.2
Quick LinksEntrez ID:6620; OMIM: 602569; Uniprot ID:SYUB_HUMAN; ENSEMBL ID: ENSG00000074317; HGNC ID: 11140
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
118Phosphoserine; by BARK1, CK2 and GRK5.
Location(AA) Modifications Resource
118Phosphoserine (by BARK1, CK2 and GRK5).Swiss-Prot 53.0
Location(AA) Modification Resource
59Phosphothreonine(CK2)HMM predict
119Phosphotyrosine(EGFR)HMM predict
119Phosphotyrosine(INSR)HMM predict
119Phosphotyrosine(Abl)HMM predict
119Phosphotyrosine(Syk)HMM predict
119SulfotyrosineHMM predict
119PhosphotyrosineHMM predict
127Phosphotyrosine(Syk)HMM predict
127SulfotyrosineHMM predict
130Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001001502
  • Location:chr5 175979816-175990162
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 175997072 175997509 437 7128
H3K27me3 colorectalcancer 175990485 175991233 748 697
H3K27me3 colorectalcancer 175993302 175993921 619 3449
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 175978982 175979147 165 752
CTCF CD4SISSRdata 175978982 175979147 165 752
CTCF G2GSE9613 175978627 175980374 1747 316
Gata2 K562GSE18868 175978790 175979317 527 763
NRSF mAbJurkat 175977239 175978232 993 2081
hScc1 BcellGSE12603 175979070 175979286 216 639
p130 SenescentGSE19898 175978968 175979241 273 712
p130 SenescentGSE19898 175979391 175979674 283 284
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 175981120 175981796 676 0
CTCF G2GSE9613 175987098 175988038 940 0
CTCF G2GSE9613 175988864 175990015 1151 0
H3K27me3 colorectalcancer 175987523 175987744 221 0
hScc1 BcellGSE12603 175989225 175990015 790 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018