AutismKB 2.0

Annotation Detail for FSCN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FSCN1 ( FLJ38511,SNL,p55 )
Gene Full Name: fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
Band: 7p22.1
Quick LinksEntrez ID:6624; OMIM: 602689; Uniprot ID:FSCN1_HUMAN; ENSEMBL ID: ENSG00000075618; HGNC ID: 11148
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylthreonine.
38Phosphoserine.
39Phosphoserine; by PKC.
471N6-acetyllysine.
Location(AA) Modifications Resource
2N-acetylthreonine (Probable).Swiss-Prot 53.0
38Phosphoserine (PKC
39Phosphoserine (by PKC).Swiss-Prot 53.0
Location(AA) Modification Resource
34N-linkedHMM predict
77N-linkedHMM predict
127Phosphoserine(IKK)HMM predict
127Phosphoserine(CDC2)HMM predict
148Phosphothreonine(PKC)HMM predict
239Phosphothreonine(PKC)HMM predict
325O-linkedHMM predict
326O-linkedHMM predict
331N-linkedHMM predict
346Phosphothreonine(PKA)HMM predict
346Phosphothreonine(PKC)HMM predict
401Phosphothreonine(PKA)HMM predict
407N-linkedHMM predict
439O-linkedHMM predict
444Phosphoserine(IKK)HMM predict
458Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003088
  • Location:chr7 5598979-5612810
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 5580564 5581392 828 18002
CTCF G2GSE9613 5592580 5592875 295 6252
CTCF G2GSE9613 5594558 5594859 301 4271
CTCF G2GSE9613 5596131 5596522 391 2653
CTCF G2GSE9613 5596997 5597171 174 1896
Gata2 K562GSE18868 5580254 5581516 1262 18095
NFkBII GM10847GSE19485 5588267 5589457 1190 10118
NFkBII GM10847GSE19485 5597348 5599566 2218 523
NFkBII GM12878GSE19485 5588101 5590668 2567 9595
NFkBII GM12878GSE19485 5590752 5591906 1154 7651
NFkBII GM12878GSE19485 5597263 5599502 2239 597
NFkBII GM12892GSE19485 5588264 5589281 1017 10207
NFkBII GM12892GSE19485 5597307 5599556 2249 548
NFkBII GM15510GSE19485 5588254 5589613 1359 10046
NFkBII GM15510GSE19485 5597327 5599569 2242 532
NFkBII GM18526GSE19485 5588330 5589594 1264 10018
TFAP2C MCF7GSE21234 5580322 5580732 410 18453
TFAP2C MCF7GSE21234 5592357 5593016 659 6293
hScc1 G2GSE9613 5598044 5598606 562 655
p130 QuiescentGSE19898 5598511 5598715 204 367
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 5613256 5613686 430 661
CTCF G2GSE9613 5615611 5615977 366 2984
hScc1 BcellGSE12603 5613233 5613583 350 598
hScc1 G2GSE9613 5615568 5615977 409 2962
hScc1 G2GSE9613 5616604 5617005 401 3994
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 5598044 5600058 2014 0
CTCF G2GSE9613 5600416 5600956 540 0
CTCF G2GSE9613 5601558 5601968 410 0
CTCF G2GSE9613 5603007 5603187 180 0
CTCF G2GSE9613 5604759 5605175 416 0
CTCF G2GSE9613 5609175 5609728 553 0
CTCF G2GSE9613 5610010 5610564 554 0
CTCF G2GSE9613 5611393 5611768 375 0
CTCF G2GSE9613 5612206 5612573 367 0
Pol2 GM12878GSE19551 5598664 5599774 1110 0
Rb SenescentGSE19898 5600491 5600732 241 0
Rb SenescentGSE19898 5601207 5601781 574 0
TFAP2C MCF7GSE21234 5600926 5601447 521 0
hScc1 BcellGSE12603 5598870 5599563 693 0
hScc1 BcellGSE12603 5611494 5611789 295 0
hScc1 G2GSE9613 5600534 5601040 506 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-133a hsa-mir-133a-1 18 21351259
hsa-miR-133a hsa-mir-133a-2 20 21351259
hsa-miR-133a hsa-mir-133a-1 18 20198616
hsa-miR-133a hsa-mir-133a-2 20 20198616
hsa-miR-133a hsa-mir-133a-1 18 20160723
hsa-miR-133a hsa-mir-133a-2 20 20160723
hsa-miR-133b hsa-mir-133b 6 21351259
hsa-miR-133b hsa-mir-133b 6 20198616
hsa-miR-143 hsa-mir-143 5 21218087
hsa-miR-143* hsa-mir-143 5 21218087
hsa-miR-145 hsa-mir-145 5 21351259
hsa-miR-145 hsa-mir-145 5 21218087
hsa-miR-145 hsa-mir-145 5 20198616
hsa-miR-145 hsa-mir-145 5 20160723
hsa-miR-145 hsa-mir-145 5 20098684
hsa-miR-145* hsa-mir-145 5 21351259
hsa-miR-145* hsa-mir-145 5 21218087
hsa-miR-145* hsa-mir-145 5 20198616
hsa-miR-145* hsa-mir-145 5 20160723
hsa-miR-145* hsa-mir-145 5 20098684
hsa-miR-183 hsa-mir-183 7 19699278
hsa-miR-183* hsa-mir-183 7 19699278
hsa-miR-96 hsa-mir-96 7 19699278
hsa-miR-96* hsa-mir-96 7 19699278
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23605 mRNA FSCN1 chr7 5405694 5419526 361 EST chr7 5419103 5419464Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved