Annotation Detail for BNIP2

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Basic Information Top

Gene Symbol:	BNIP2 ( BNIP-2,NIP2 )
Gene Full Name:	BCL2/adenovirus E1B 19kDa interacting protein 2
Band:	15q22.2
Quick Links	Entrez ID:663; OMIM: 603292; Uniprot ID:BNIP2_HUMAN; ENSEMBL ID: ENSG00000140299; HGNC ID: 1083
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:7 results

Location(AA)	Modification
114	Phosphoserine.
116	Phosphothreonine.

Location(AA)	Modification	Resource
68	Phosphoserine(IKK)	HMM predict
87	Phosphothreonine(MAPK)	HMM predict
87	Phosphothreonine(CDK)	HMM predict
114	Phosphoserine(PKA)	HMM predict
114	Phosphoserine(PKG)	HMM predict
216	Phosphothreonine(PKC)	HMM predict
265	Phosphoserine(CDK)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_004330
Location:chr15 57742355-57768777
strand:-

Upstream the gene:6 results
Downstream the gene:0 results
Inside the gene:14 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Myc	K562	GSE19551	57775770	57776253	483	7234
PHF8	HeLa	GSE20725	57768177	57769379	1202	1
Rb	Senescent	GSE19898	57768795	57769449	654	345
TFAP2C	MCF7	GSE21234	57768765	57769199	434	205
p130	Quiescent	GSE19898	57768900	57769042	142	194
p130	Senescent	GSE19898	57768886	57769096	210	214

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	57768434	57768795	361	0
ETS1	Jurkat	GSE17954	57767826	57769364	1538	0
GABP	k562	GSE8489	57767135	57768249	1114	0
H3K4me3	colorectal	cancer	57767135	57768287	1152	0
H3ac	HepG2	E	57767135	57767498	363	0
H3ac	HepG2	E	57767768	57768516	748	0
Rb	Growing	GSE19898	57768464	57768634	170	0
TAF	Hela	GSE8489	57767171	57768287	1116	0
p130	Quiescent	GSE19898	57768032	57768473	441	0
p130	Quiescent	GSE19898	57768478	57768836	358	0
p130	Senescent	GSE19898	57767909	57768534	625	0
p130	Senescent	GSE19898	57768560	57768747	187	0
p130	shRbQuiescent	GSE19898	57767724	57768640	916	0
p130	shRbSenescent	GSE19898	57767949	57768917	968	0

Validated miRNA targets

miR Walk:2 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-20a	hsa-mir-20a	13	21242194
hsa-miR-20a*	hsa-mir-20a	13	21242194

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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