Annotation Detail for SOAT1

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	SOAT1 ( ACACT,ACAT,ACAT1,RP11-215I23.2,SOAT,STAT )
Gene Full Name:	sterol O-acyltransferase 1
Band:	1q25.2
Quick Links	Entrez ID:6646; OMIM: 102642; Uniprot ID:SOAT1_HUMAN; ENSEMBL ID: ENSG00000057252; HGNC ID: 11177
Relate to Another Database:	SFARIGene; denovo-db

General

Expression

Regulation

Pathways, Diseases and Drugs

PTM

TF binding site

miRNA targets

Cis-NATs

Post Translation Modification

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PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:12 results

No data

Location(AA)	Modification	Resource
33	Phosphoserine(PKG)	HMM predict
127	Phosphoserine(PKG)	HMM predict
287	O-linked	HMM predict
288	Phosphothreonine(PKC)	HMM predict
315	N-linked	HMM predict
317	Phosphothreonine(PKC)	HMM predict
409	N-linked	HMM predict
414	O-linked	HMM predict
415	N-linked	HMM predict
491	N-linked	HMM predict
532	N-linked	HMM predict
546	Cysteine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_003101
Location:chr1 177529639-177591074
strand:+

Upstream the gene:7 results
Downstream the gene:0 results
Inside the gene:8 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	Jurkat	GSE12889	177528201	177528382	181	1348
CTCF	G2	GSE9613	177528055	177528446	391	1389
CTCF	G2	GSE9613	177529194	177529827	633	129
Nanog	hES	GSE18292	177516766	177517096	330	12709
Oct1	Hela	GSE14283	177522305	177522376	71	7299
hScc1	Bcell	GSE12603	177528087	177528608	521	1292
hScc1	CdLS	GSE12603	177527910	177528587	677	1391

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CBP	T0-glioblastoma	GSE21026	177553458	177554028	570
ER	Fulvestrant-MCF7	GSE14664	177536558	177536594	36
H3ac	HepG2	E	177530601	177531228	627
NFkBII	GM12878	GSE19485	177530289	177531806	1517
Nanog	hES	GSE18292	177532063	177532480	417
Nanog	hES	GSE18292	177566920	177567242	322
Oct1	H2O2-Hela	GSE14283	177591020	177591052	32
hScc1	Bcell	GSE12603	177529544	177529827	283

Validated miRNA targets

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miR Walk:88 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7a	hsa-let-7a-1	9	17220301
hsa-let-7a	hsa-let-7a-2	11	17220301
hsa-let-7a	hsa-let-7a-3	22	17220301
hsa-let-7a	hsa-let-7a-1	9	17220301
hsa-let-7a	hsa-let-7a-2	11	17220301
hsa-let-7a	hsa-let-7a-3	22	17220301
hsa-let-7a*	hsa-let-7a-1	9	17220301
hsa-let-7a*	hsa-let-7a-1	9	17220301
hsa-miR-151-3p	hsa-mir-151	8	20445018
hsa-miR-151-3p	hsa-mir-151	8	20445018
hsa-miR-151-5p	hsa-mir-151	8	20445018
hsa-miR-151-5p	hsa-mir-151	8	20445018
hsa-miR-155	hsa-mir-155	21	20950585
hsa-miR-155	hsa-mir-155	21	19651781
hsa-miR-155	hsa-mir-155	21	20950585
hsa-miR-155	hsa-mir-155	21	19651781
hsa-miR-155*	hsa-mir-155	21	20950585
hsa-miR-155*	hsa-mir-155	21	19651781
hsa-miR-155*	hsa-mir-155	21	20950585
hsa-miR-155*	hsa-mir-155	21	19651781
hsa-miR-17	hsa-mir-17	13	17934639
hsa-miR-17	hsa-mir-17	13	17934639
hsa-miR-17*	hsa-mir-17	13	17934639
hsa-miR-17*	hsa-mir-17	13	17934639
hsa-miR-181b	hsa-mir-181b-1	1	17934639
hsa-miR-181b	hsa-mir-181b-2	9	17934639
hsa-miR-181b	hsa-mir-181b-1	1	17934639
hsa-miR-181b	hsa-mir-181b-2	9	17934639
hsa-miR-195	hsa-mir-195	17	17934639
hsa-miR-195	hsa-mir-195	17	17934639
hsa-miR-195*	hsa-mir-195	17	17934639
hsa-miR-195*	hsa-mir-195	17	17934639
hsa-miR-196a	hsa-mir-196a-1	17	19085952
hsa-miR-196a	hsa-mir-196a-2	12	19085952
hsa-miR-196a	hsa-mir-196a-1	17	19085952
hsa-miR-196a	hsa-mir-196a-2	12	19085952
hsa-miR-204	hsa-mir-204	9	17934639
hsa-miR-204	hsa-mir-204	9	17934639
hsa-miR-218	hsa-mir-218-1	4	17934639
hsa-miR-218	hsa-mir-218-2	5	17934639
hsa-miR-218	hsa-mir-218-1	4	17934639
hsa-miR-218	hsa-mir-218-2	5	17934639
hsa-miR-221	hsa-mir-221	X	20428775
hsa-miR-221	hsa-mir-221	X	20428775
hsa-miR-221*	hsa-mir-221	X	20428775
hsa-miR-221*	hsa-mir-221	X	20428775
hsa-miR-222	hsa-mir-222	X	20428775
hsa-miR-222	hsa-mir-222	X	20428775
hsa-miR-222*	hsa-mir-222	X	20428775
hsa-miR-222*	hsa-mir-222	X	20428775
hsa-miR-28-3p	hsa-mir-28	3	20445018
hsa-miR-28-3p	hsa-mir-28	3	20445018
hsa-miR-28-5p	hsa-mir-28	3	20445018
hsa-miR-28-5p	hsa-mir-28	3	20445018
hsa-miR-29a	hsa-mir-29a	7	17934639
hsa-miR-29a	hsa-mir-29a	7	17934639
hsa-miR-29a*	hsa-mir-29a	7	17934639
hsa-miR-29a*	hsa-mir-29a	7	17934639
hsa-miR-29c	hsa-mir-29c	1	17934639
hsa-miR-29c	hsa-mir-29c	1	17934639
hsa-miR-29c*	hsa-mir-29c	1	17934639
hsa-miR-29c*	hsa-mir-29c	1	17934639
hsa-miR-30b	hsa-mir-30b	8	17934639
hsa-miR-30b	hsa-mir-30b	8	17934639
hsa-miR-30b*	hsa-mir-30b	8	17934639
hsa-miR-30b*	hsa-mir-30b	8	17934639
hsa-miR-331-3p	hsa-mir-331	12	17934639
hsa-miR-331-3p	hsa-mir-331	12	17934639
hsa-miR-331-5p	hsa-mir-331	12	17934639
hsa-miR-331-5p	hsa-mir-331	12	17934639
hsa-miR-34a	hsa-mir-34a	1	17934639
hsa-miR-34a	hsa-mir-34a	1	17934639
hsa-miR-34a*	hsa-mir-34a	1	17934639
hsa-miR-34a*	hsa-mir-34a	1	17934639
hsa-miR-708	hsa-mir-708	11	20445018
hsa-miR-708	hsa-mir-708	11	20445018
hsa-miR-708*	hsa-mir-708	11	20445018
hsa-miR-708*	hsa-mir-708	11	20445018
hsa-miR-9	hsa-mir-9-1	1	16357340
hsa-miR-9	hsa-mir-9-2	5	16357340
hsa-miR-9	hsa-mir-9-3	15	16357340
hsa-miR-9	hsa-mir-9-1	1	16357340
hsa-miR-9	hsa-mir-9-2	5	16357340
hsa-miR-9	hsa-mir-9-3	15	16357340
hsa-miR-92a	hsa-mir-92a-1	13	17934639
hsa-miR-92a	hsa-mir-92a-2	X	17934639
hsa-miR-92a	hsa-mir-92a-1	13	17934639
hsa-miR-92a	hsa-mir-92a-2	X	17934639

Cis-Nats regulation

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Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
1991	mRNA	SOAT1	chr1	175994673	176056109	136	EST		chr1	176050922	176051254	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

AutismKB 2.0

Annotation Detail for SOAT1

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics