AutismKB 2.0

Annotation Detail for SON


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Basic Information Top
Gene Symbol:SON ( BASS1,C21orf50,DBP-5,FLJ21099,FLJ33914,KIAA1019,NREBP,SON3 )
Gene Full Name: SON DNA binding protein
Band: 21q22.11
Quick LinksEntrez ID:6651; OMIM: 182465; Uniprot ID:SON_HUMAN; ENSEMBL ID: ENSG00000159140; HGNC ID: 11183
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
16N6-acetyllysine.
94Phosphoserine.
152Phosphoserine.
154Phosphoserine.
283Phosphoserine.
288N6-acetyllysine.
348Phosphoserine.
908Phosphoserine.
910Phosphoserine.
1051Phosphoserine.
1076Phosphoserine.
1556Phosphoserine.
1651Phosphoserine.
1688Phosphoserine (By similarity).
1697Phosphoserine.
1766Phosphoserine.
1769Phosphoserine.
1782Phosphoserine.
1783Phosphoserine.
1784Phosphoserine (By similarity).
1820Phosphoserine (By similarity).
1821Phosphoserine (By similarity).
1824Phosphoserine (By similarity).
1948Phosphoserine.
1950Phosphoserine.
1954Phosphoserine.
1961Phosphoserine (By similarity).
2009Phosphoserine.
2011Phosphoserine.
2013Phosphoserine.
2029Phosphoserine.
2031Phosphoserine.
2055N6-acetyllysine.
2129Phosphoserine.
2163Phosphothreonine.
Location(AA) Modifications Resource
94Phosphoserine.Swiss-Prot 53.0
94PhosphoserinePhospho.ELM 6.0
154Phosphoserine.Swiss-Prot 53.0
154PhosphoserinePhospho.ELM 6.0
283PhosphoserinePhospho.ELM 6.0
283Phosphoserine.Swiss-Prot 53.0
910Phosphoserine.Swiss-Prot 53.0
910PhosphoserinePhospho.ELM 6.0
1556PhosphoserinePhospho.ELM 6.0
1651Phosphoserine.Swiss-Prot 53.0
1651PhosphoserinePhospho.ELM 6.0
1688Phosphoserine (By similarity).Swiss-Prot 53.0
1697PhosphoserinePhospho.ELM 6.0
1697Phosphoserine.Swiss-Prot 53.0
1766Phosphoserine.Swiss-Prot 53.0
1766PhosphoserinePhospho.ELM 6.0
1769Phosphoserine.Swiss-Prot 53.0
1769PhosphoserinePhospho.ELM 6.0
1784Phosphoserine (By similarity).Swiss-Prot 53.0
1922PhosphoserinePhospho.ELM 6.0
1924PhosphothreoninePhospho.ELM 6.0
1948PhosphoserinePhospho.ELM 6.0
1948Phosphoserine (By similarity).Swiss-Prot 53.0
1950PhosphoserinePhospho.ELM 6.0
1950Phosphoserine (By similarity).Swiss-Prot 53.0
1954PhosphoserinePhospho.ELM 6.0
1961Phosphoserine (By similarity).Swiss-Prot 53.0
2009PhosphoserinePhospho.ELM 6.0
2009Phosphoserine.Swiss-Prot 53.0
2011Phosphoserine.Swiss-Prot 53.0
2011PhosphoserinePhospho.ELM 6.0
2013PhosphoserinePhospho.ELM 6.0
2013Phosphoserine.Swiss-Prot 53.0
2020PhosphoserinePhospho.ELM 6.0
2029PhosphoserinePhospho.ELM 6.0
2029Phosphoserine.Swiss-Prot 53.0
2031PhosphoserinePhospho.ELM 6.0
2031Phosphoserine.Swiss-Prot 53.0
2055N6-acetyllysine.Swiss-Prot 53.0
2129Phosphoserine.Swiss-Prot 53.0
2129PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
25Phosphoserine(CK1)HMM predict
90PhosphoserineHMM predict
94Phosphoserine(IKK)HMM predict
105Phosphothreonine(PKC)HMM predict
136Phosphoserine(CK1)HMM predict
138Phosphoserine(CK1)HMM predict
180N-linkedHMM predict
182Phosphoserine(CDC2)HMM predict
252O-linkedHMM predict
278Phosphoserine(IKK)HMM predict
283Phosphoserine(CDC2)HMM predict
283Phosphoserine(MAPK)HMM predict
283Phosphoserine(CDK)HMM predict
310O-linkedHMM predict
312Phosphothreonine(MAPK)HMM predict
317Phosphotyrosine(Syk)HMM predict
325O-linkedHMM predict
400Phosphothreonine(MAPK)HMM predict
400Phosphothreonine(CDK)HMM predict
409O-linkedHMM predict
411O-linkedHMM predict
411Phosphothreonine(MAPK)HMM predict
422O-linkedHMM predict
422Phosphothreonine(MAPK)HMM predict
433O-linkedHMM predict
442O-linkedHMM predict
444O-linkedHMM predict
444O-linkedHMM predict
444Phosphothreonine(MAPK)HMM predict
444Phosphothreonine(CDK)HMM predict
498O-linkedHMM predict
531O-linkedHMM predict
648O-linkedHMM predict
665O-linkedHMM predict
666O-linkedHMM predict
670Phosphoserine(ATM)HMM predict
770Phosphoserine(IKK)HMM predict
780Phosphoserine(IKK)HMM predict
800Phosphoserine(IKK)HMM predict
810Phosphoserine(IKK)HMM predict
820Phosphoserine(IKK)HMM predict
830Phosphoserine(IKK)HMM predict
860Phosphoserine(IKK)HMM predict
1132SulfotyrosineHMM predict
1136SulfotyrosineHMM predict
1140Phosphotyrosine(INSR)HMM predict
1140Phosphotyrosine(Syk)HMM predict
1144Phosphotyrosine(INSR)HMM predict
1144Phosphotyrosine(Syk)HMM predict
1156O-linkedHMM predict
1168Phosphothreonine(CDK)HMM predict
1197O-linkedHMM predict
1204Phosphoserine(CK1)HMM predict
1207Phosphoserine(CK1)HMM predict
1207Phosphoserine(IKK)HMM predict
1209O-linkedHMM predict
1209O-linkedHMM predict
1209Phosphoserine(ATM)HMM predict
1209Phosphoserine(IKK)HMM predict
1216O-linkedHMM predict
1216Phosphoserine(ATM)HMM predict
1221Phosphoserine(CK1)HMM predict
1224O-linkedHMM predict
1231Phosphoserine(IKK)HMM predict
1233O-linkedHMM predict
1242O-linkedHMM predict
1247Phosphothreonine(PKC)HMM predict
1258O-linkedHMM predict
1258Phosphoserine(CK1)HMM predict
1262O-linkedHMM predict
1292O-linkedHMM predict
1318Phosphoserine(PKG)HMM predict
1323O-linkedHMM predict
1336Phosphothreonine(CDK)HMM predict
1374O-linkedHMM predict
1402Phosphotyrosine(EGFR)HMM predict
1437Phosphoserine(CK1)HMM predict
1439O-linkedHMM predict
1439Phosphoserine(ATM)HMM predict
1448O-linkedHMM predict
1453Phosphothreonine(PKC)HMM predict
1455O-linkedHMM predict
1526Phosphoserine(CK2)HMM predict
1631Phosphoserine(CK1)HMM predict
1646Phosphoserine(CDC2)HMM predict
1697Phosphoserine(MAPK)HMM predict
1747Phosphoserine(PKB)HMM predict
1766Phosphoserine(IKK)HMM predict
1769Phosphoserine(CDC2)HMM predict
1769Phosphoserine(MAPK)HMM predict
1780Phosphoserine(CK2)HMM predict
1780Phosphoserine(IKK)HMM predict
1782Phosphoserine(CK2)HMM predict
1783Phosphoserine(CK1)HMM predict
1783Phosphoserine(CK2)HMM predict
1784Phosphoserine(CK1)HMM predict
1790Phosphotyrosine(EGFR)HMM predict
1820Phosphoserine(CK1)HMM predict
1840Phosphothreonine(PKA)HMM predict
1840Phosphothreonine(PKC)HMM predict
1841Phosphoserine(CAMK2)HMM predict
1859Phosphoserine(ATM)HMM predict
1861Phosphothreonine(PKC)HMM predict
1878Phosphoserine(CK1)HMM predict
1881MethylarginineHMM predict
1885Phosphoserine(PKG)HMM predict
1894Phosphoserine(CDC2)HMM predict
1894PhosphoserineHMM predict
1909Phosphoserine(PKG)HMM predict
1917Phosphothreonine(PKC)HMM predict
1922PhosphoserineHMM predict
1924Phosphothreonine(MAPK)HMM predict
1924Phosphothreonine(CDK)HMM predict
1926PhosphoserineHMM predict
1933Phosphothreonine(CDC2)HMM predict
1933Phosphothreonine(MAPK)HMM predict
1933Phosphothreonine(CDK)HMM predict
1935Phosphoserine(PKC)HMM predict
1940Phosphoserine(PKG)HMM predict
1948Phosphoserine(PKA)HMM predict
1948Phosphoserine(IKK)HMM predict
1948Phosphoserine(PKB)HMM predict
1950Phosphoserine(PKB)HMM predict
1952Phosphoserine(CDC2)HMM predict
1957Phosphoserine(PKA)HMM predict
1959Phosphothreonine(MAPK)HMM predict
1959Phosphothreonine(CDK)HMM predict
1961PhosphoserineHMM predict
1964Phosphoserine(PKA)HMM predict
1966Phosphothreonine(MAPK)HMM predict
1966Phosphothreonine(CDK)HMM predict
1968PhosphoserineHMM predict
1971Phosphoserine(PKA)HMM predict
1973Phosphothreonine(MAPK)HMM predict
1973Phosphothreonine(CDK)HMM predict
1975PhosphoserineHMM predict
1978Phosphoserine(PKA)HMM predict
1980Phosphothreonine(MAPK)HMM predict
1980Phosphothreonine(CDK)HMM predict
1982PhosphoserineHMM predict
1985Phosphoserine(PKA)HMM predict
1987Phosphothreonine(MAPK)HMM predict
1987Phosphothreonine(CDK)HMM predict
1989PhosphoserineHMM predict
1992Phosphoserine(PKA)HMM predict
1994Phosphothreonine(MAPK)HMM predict
1994Phosphothreonine(CDK)HMM predict
1996PhosphoserineHMM predict
2001Phosphoserine(PKG)HMM predict
2009Phosphoserine(PKA)HMM predict
2011Phosphoserine(PKB)HMM predict
2013Phosphoserine(CDC2)HMM predict
2020Phosphoserine(PKG)HMM predict
2022Phosphothreonine(MAPK)HMM predict
2022Phosphothreonine(CDK)HMM predict
2029Phosphoserine(PKG)HMM predict
2031Phosphoserine(CDC2)HMM predict
2031Phosphoserine(CDK)HMM predict
2038Phosphoserine(PKG)HMM predict
2040Phosphoserine(CK1)HMM predict
2040PhosphoserineHMM predict
2046Phosphoserine(CDC2)HMM predict
2129Phosphoserine(CK2)HMM predict
2129PhosphoserineHMM predict
2163Phosphothreonine(MAPK)HMM predict
2163Phosphothreonine(CDK)HMM predict
2265Phosphoserine(IKK)HMM predict
2396Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032195
  • Location:chr21 33837219-33854840
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 33835896 33838207 2311 168
FOXA1 MCF7GSE15244 33836013 33838297 2284 65
Fos K562GSE19551 33835974 33837870 1896 298
H3ac HepG2E 33835604 33838680 3076 78
LIN9 SGSE7516 33836494 33837582 1088 182
PHF8 HeLaGSE20725 33835768 33837815 2047 428
PHF8 Hs68minusFBSGSE20725 33835923 33838137 2214 190
PHF8 Hs68plusFBSGSE20725 33835751 33838229 2478 230
RARG MCF7GSE15244 33836528 33837294 766 309
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 33845576 33846010 434 0
H3K4me3 colorectalcancer 33837920 33839225 1305 0
RARA MCF7GSE15244 33845540 33846255 715 0
TAF k562GSE8489 33837885 33839083 1198 0
hScc1 BcellGSE12603 33844486 33844961 475 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
16892 mRNA SON chr21 33837219 33871655 186 EST chr21 33853717 33872539Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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