AutismKB 2.0

Annotation Detail for SOS2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SOS2 ( FLJ25596 )
Gene Full Name: son of sevenless homolog 2 (Drosophila)
Band: 14q21.3
Quick LinksEntrez ID:6655; OMIM: 601247; Uniprot ID:SOS2_HUMAN; ENSEMBL ID: ENSG00000100485; HGNC ID: 11188
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
158Phosphoserine(ATM)HMM predict
194Phosphoserine(CK1)HMM predict
240Phosphotyrosine(EGFR)HMM predict
240Phosphotyrosine(Syk)HMM predict
246N-linkedHMM predict
293Phosphotyrosine(Syk)HMM predict
384Phosphoserine(PKA)HMM predict
481Phosphotyrosine(INSR)HMM predict
547Phosphothreonine(PKC)HMM predict
569Phosphoserine(MAPK)HMM predict
573Phosphotyrosine(Abl)HMM predict
573Phosphotyrosine(SRC)HMM predict
699Phosphotyrosine(Syk)HMM predict
700Phosphotyrosine(Jak)HMM predict
700SulfotyrosineHMM predict
749N-linkedHMM predict
828N-linkedHMM predict
906Phosphoserine(ATM)HMM predict
1030Phosphothreonine(PKA)HMM predict
1035Phosphoserine(CDC2)HMM predict
1047Phosphoserine(IKK)HMM predict
1057Phosphothreonine(CDK)HMM predict
1057Phosphothreonine(MAPK)HMM predict
1078O-linkedHMM predict
1081Phosphoserine(IKK)HMM predict
1084O-linkedHMM predict
1084O-linkedHMM predict
1085Phosphoserine(IKK)HMM predict
1085O-linkedHMM predict
1085Phosphoserine(CDK)HMM predict
1085O-linkedHMM predict
1088Phosphothreonine(MAPK)HMM predict
1088O-linkedHMM predict
1090O-linkedHMM predict
1090O-linkedHMM predict
1091Phosphothreonine(MAPK)HMM predict
1091PhosphothreonineHMM predict
1091O-linkedHMM predict
1095O-linkedHMM predict
1098Phosphoserine(CK1)HMM predict
1109N-linkedHMM predict
1115N-linkedHMM predict
1202Phosphoserine(MAPK)HMM predict
1202Phosphoserine(ATM)HMM predict
1202O-linkedHMM predict
1215Phosphothreonine(MAPK)HMM predict
1215Phosphothreonine(CDC2)HMM predict
1258Phosphoserine(CDC2)HMM predict
1260O-linkedHMM predict
1260O-linkedHMM predict
1261Phosphothreonine(CDK)HMM predict
1261Phosphothreonine(MAPK)HMM predict
1261O-linkedHMM predict
1261Phosphothreonine(CDC2)HMM predict
1264Phosphoserine(IKK)HMM predict
1265Phosphothreonine(MAPK)HMM predict
1267O-linkedHMM predict
1267Phosphoserine(CDK)HMM predict
1267Phosphoserine(CDC2)HMM predict
1297N-linkedHMM predict
1299Phosphoserine(CDC2)HMM predict
1315Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006939
  • Location:chr14 49654812-49767750
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 49767573 49768526 953 299
H3ac HepG2E 49769082 49769689 607 1635
PHF8 HeLaGSE20725 49767214 49769040 1826 377
hScc1 BcellGSE12603 49767214 49768526 1312 120
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 49711879 49711911 32 0
ER Fulvestrant-MCF7GSE14664 49661206 49661242 36 0
H3K4me3 colorectalcancer 49767032 49767408 376 0
H3ac HepG2E 49766851 49767296 445 0
Nanog ESGSE20650 49675673 49676041 368 0
Nanog hESGSE18292 49675669 49675920 251 0
Oct1 H2O2-HelaGSE14283 49762477 49762507 30 0
Oct1 HelaGSE14283 49661201 49661240 39 0
Oct1 HelaGSE14283 49701812 49701845 33 0
Oct1 HelaGSE14283 49711040 49711081 41 0
Oct1 HelaGSE14283 49733178 49733207 29 0
Oct1 HelaGSE14283 49762477 49762507 30 0
TAF k562GSE8489 49766521 49767535 1014 0
TFAP2C MCF7GSE21234 49767035 49767569 534 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved