AutismKB 2.0

Annotation Detail for SOX2


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Basic Information Top
Gene Symbol:SOX2 ( ANOP3,MCOPS3,MGC2413 )
Gene Full Name: SRY (sex determining region Y)-box 2
Band: 3q26.33
Quick LinksEntrez ID:6657; OMIM: 184429; Uniprot ID:SOX2_HUMAN; ENSEMBL ID: ENSG00000181449; HGNC ID: 11195
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
24N-linkedHMM predict
37Phosphoserine(CDC2)HMM predict
116Phosphothreonine(PKA)HMM predict
118Phosphothreonine(PKC)HMM predict
125Phosphotyrosine(INSR)HMM predict
171Phosphotyrosine(SRC)HMM predict
171Phosphotyrosine(INSR)HMM predict
213Phosphoserine(ATM)HMM predict
216Phosphotyrosine(INSR)HMM predict
218N-linkedHMM predict
228Phosphoserine(ATM)HMM predict
249O-linkedHMM predict
250O-linkedHMM predict
251O-linkedHMM predict
261O-linkedHMM predict
309N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003106
  • Location:chr3 182912415-182914914
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 182900894 182901213 319 11362
CTCF CD4GSE12889 182910103 182910394 291 2167
CTCF CD4SISSRdata 182900894 182901213 319 11362
CTCF CD4SISSRdata 182910103 182910394 291 2167
CTCF G2GSE9613 182895466 182896207 741 16579
CTCF G2GSE9613 182896466 182896762 296 15802
CTCF G2GSE9613 182900719 182901689 970 11212
CTCF G2GSE9613 182902490 182903086 596 9628
CTCF G2GSE9613 182904286 182904643 357 7951
CTCF G2GSE9613 182909956 182910400 444 2238
FOXA1 MCF7GSE15244 182911472 182912061 589 649
H3K27me3 colorectalcancer 182904974 182906524 1550 6667
H3K27me3 colorectalcancer 182910175 182911984 1809 1336
hScc1 BcellGSE12603 182895614 182896686 1072 16266
hScc1 BcellGSE12603 182910068 182910487 419 2138
hScc1 CdLSGSE12603 182900830 182901569 739 11216
hScc1 CdLSGSE12603 182909809 182911027 1218 1998
hScc1 G2GSE9613 182900753 182901796 1043 11141
hScc1 G2GSE9613 182909912 182910603 691 2158
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 182915723 182915970 247 932
CBP T30-glioblastomaGSE21026 182915778 182915973 195 961
CTCF G2GSE9613 182919795 182920239 444 5103
CTCF G2GSE9613 182926495 182926719 224 11693
CTCF G2GSE9613 182927665 182927920 255 12878
FOXA1 MCF7GSE15244 182921668 182922360 692 7100
Oct4 hESGSE21916 182915962 182916972 1010 1553
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 182912687 182913846 1159 0
H3K27me3 colorectalcancer 182913783 182914397 614 0
hScc1 BcellGSE12603 182912554 182913543 989 0
hScc1 G2GSE9613 182912395 182913846 1451 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20947512
hsa-let-7a hsa-let-7a-2 11 20947512
hsa-let-7a hsa-let-7a-3 22 20947512
hsa-let-7a hsa-let-7a-1 9 19492978
hsa-let-7a hsa-let-7a-2 11 19492978
hsa-let-7a hsa-let-7a-3 22 19492978
hsa-let-7a hsa-let-7a-1 9 20179095
hsa-let-7a hsa-let-7a-2 11 20179095
hsa-let-7a hsa-let-7a-3 22 20179095
hsa-let-7a* hsa-let-7a-1 9 20947512
hsa-let-7a* hsa-let-7a-3 22 20947512
hsa-let-7a* hsa-let-7a-1 9 19492978
hsa-let-7a* hsa-let-7a-3 22 19492978
hsa-let-7a* hsa-let-7a-1 9 20179095
hsa-let-7a* hsa-let-7a-3 22 20179095
hsa-let-7b hsa-let-7b 22 20947512
hsa-let-7b hsa-let-7b 22 19492978
hsa-let-7b hsa-let-7b 22 20179095
hsa-let-7b* hsa-let-7b 22 20947512
hsa-let-7b* hsa-let-7b 22 19492978
hsa-let-7b* hsa-let-7b 22 20179095
hsa-let-7c hsa-let-7c 21 20947512
hsa-let-7c hsa-let-7c 21 19492978
hsa-let-7c hsa-let-7c 21 20179095
hsa-let-7c* hsa-let-7c 21 20947512
hsa-let-7c* hsa-let-7c 21 19492978
hsa-let-7c* hsa-let-7c 21 20179095
hsa-let-7d hsa-let-7d 9 20947512
hsa-let-7d hsa-let-7d 9 19492978
hsa-let-7d hsa-let-7d 9 20179095
hsa-let-7d* hsa-let-7d 9 20947512
hsa-let-7d* hsa-let-7d 9 19492978
hsa-let-7d* hsa-let-7d 9 20179095
hsa-let-7e hsa-let-7e 19 20947512
hsa-let-7e hsa-let-7e 19 19492978
hsa-let-7e hsa-let-7e 19 20179095
hsa-let-7e* hsa-let-7e 19 20947512
hsa-let-7e* hsa-let-7e 19 19492978
hsa-let-7e* hsa-let-7e 19 20179095
hsa-let-7f hsa-let-7f-1 9 20947512
hsa-let-7f hsa-let-7f-2 X 20947512
hsa-let-7f hsa-let-7f-1 9 19492978
hsa-let-7f hsa-let-7f-2 X 19492978
hsa-let-7f hsa-let-7f-1 9 20179095
hsa-let-7f hsa-let-7f-2 X 20179095
hsa-let-7f-1* hsa-let-7f-1 9 20947512
hsa-let-7f-1* hsa-let-7f-1 9 19492978
hsa-let-7f-1* hsa-let-7f-1 9 20179095
hsa-let-7f-2* hsa-let-7f-2 X 20947512
hsa-let-7f-2* hsa-let-7f-2 X 19492978
hsa-let-7f-2* hsa-let-7f-2 X 20179095
hsa-let-7g hsa-let-7g 3 20947512
hsa-let-7g hsa-let-7g 3 19492978
hsa-let-7g hsa-let-7g 3 20179095
hsa-let-7g* hsa-let-7g 3 20947512
hsa-let-7g* hsa-let-7g 3 19492978
hsa-let-7g* hsa-let-7g 3 20179095
hsa-let-7i hsa-let-7i 12 20947512
hsa-let-7i hsa-let-7i 12 19492978
hsa-let-7i hsa-let-7i 12 20179095
hsa-let-7i* hsa-let-7i 12 20947512
hsa-let-7i* hsa-let-7i 12 19492978
hsa-let-7i* hsa-let-7i 12 20179095
hsa-miR-100 hsa-mir-100 11 21109969
hsa-miR-100* hsa-mir-100 11 21109969
hsa-miR-106b hsa-mir-106b 7 21285944
hsa-miR-106b* hsa-mir-106b 7 21285944
hsa-miR-125a-3p hsa-mir-125a 19 20947512
hsa-miR-125a-5p hsa-mir-125a 19 20947512
hsa-miR-125b hsa-mir-125b-1 11 20947512
hsa-miR-125b hsa-mir-125b-2 21 20947512
hsa-miR-125b-1* hsa-mir-125b-1 11 20947512
hsa-miR-125b-2* hsa-mir-125b-2 21 20947512
hsa-miR-126 hsa-mir-126 9 21304604
hsa-miR-126* hsa-mir-126 9 21304604
hsa-miR-134 hsa-mir-134 14 18806776
hsa-miR-137 hsa-mir-137 1 20368621
hsa-miR-142-3p hsa-mir-142 17 20676373
hsa-miR-143 hsa-mir-143 5 21211035
hsa-miR-143* hsa-mir-143 5 21211035
hsa-miR-145 hsa-mir-145 5 21211035
hsa-miR-145 hsa-mir-145 5 20382729
hsa-miR-145 hsa-mir-145 5 19409607
hsa-miR-145* hsa-mir-145 5 21211035
hsa-miR-145* hsa-mir-145 5 20382729
hsa-miR-145* hsa-mir-145 5 19409607
hsa-miR-155 hsa-mir-155 21 20676373
hsa-miR-155* hsa-mir-155 21 20676373
hsa-miR-17 hsa-mir-17 13 19492978
hsa-miR-17* hsa-mir-17 13 19492978
hsa-miR-183 hsa-mir-183 7 19935649
hsa-miR-183* hsa-mir-183 7 19935649
hsa-miR-1908 hsa-mir-1908 11 18583537
hsa-miR-1909 hsa-mir-1909 19 18583537
hsa-miR-1909* hsa-mir-1909 19 18583537
hsa-miR-1910 hsa-mir-1910 16 18583537
hsa-miR-1911 hsa-mir-1911 X 18583537
hsa-miR-1911* hsa-mir-1911 X 18583537
hsa-miR-1912 hsa-mir-1912 X 18583537
hsa-miR-1913 hsa-mir-1913 6 18583537
hsa-miR-1914 hsa-mir-1914 20 18583537
hsa-miR-1914* hsa-mir-1914 20 18583537
hsa-miR-1915 hsa-mir-1915 10 18583537
hsa-miR-1915* hsa-mir-1915 10 18583537
hsa-miR-200c hsa-mir-200c 12 21109969
hsa-miR-200c hsa-mir-200c 12 19935649
hsa-miR-200c* hsa-mir-200c 12 21109969
hsa-miR-200c* hsa-mir-200c 12 19935649
hsa-miR-203 hsa-mir-203 14 19935649
hsa-miR-204 hsa-mir-204 9 21109969
hsa-miR-205 hsa-mir-205 1 20621051
hsa-miR-206 hsa-mir-206 6 21109969
hsa-miR-21 hsa-mir-21 17 18362916
hsa-miR-21* hsa-mir-21 17 18362916
hsa-miR-223 hsa-mir-223 X 21109969
hsa-miR-223 hsa-mir-223 X 20676373
hsa-miR-223* hsa-mir-223 X 21109969
hsa-miR-223* hsa-mir-223 X 20676373
hsa-miR-296-3p hsa-mir-296 20 18806776
hsa-miR-296-5p hsa-mir-296 20 18806776
hsa-miR-302a hsa-mir-302a 4 20676373
hsa-miR-302a hsa-mir-302a 4 19492978
hsa-miR-302a hsa-mir-302a 4 21151097
hsa-miR-302a hsa-mir-302a 4 19280062
hsa-miR-302a hsa-mir-302a 4 18755840
hsa-miR-302a hsa-mir-302a 4 18710938
hsa-miR-302a* hsa-mir-302a 4 20676373
hsa-miR-302a* hsa-mir-302a 4 19492978
hsa-miR-302a* hsa-mir-302a 4 21151097
hsa-miR-302a* hsa-mir-302a 4 19280062
hsa-miR-302a* hsa-mir-302a 4 18755840
hsa-miR-302a* hsa-mir-302a 4 18710938
hsa-miR-302b hsa-mir-302b 4 19492978
hsa-miR-302b hsa-mir-302b 4 21151097
hsa-miR-302b hsa-mir-302b 4 19280062
hsa-miR-302b hsa-mir-302b 4 18755840
hsa-miR-302b* hsa-mir-302b 4 19492978
hsa-miR-302b* hsa-mir-302b 4 21151097
hsa-miR-302b* hsa-mir-302b 4 19280062
hsa-miR-302b* hsa-mir-302b 4 18755840
hsa-miR-302c hsa-mir-302c 4 19492978
hsa-miR-302c hsa-mir-302c 4 21151097
hsa-miR-302c hsa-mir-302c 4 19280062
hsa-miR-302c hsa-mir-302c 4 18755840
hsa-miR-302c* hsa-mir-302c 4 19492978
hsa-miR-302c* hsa-mir-302c 4 21151097
hsa-miR-302c* hsa-mir-302c 4 19280062
hsa-miR-302c* hsa-mir-302c 4 18755840
hsa-miR-302d hsa-mir-302d 4 20676373
hsa-miR-302d hsa-mir-302d 4 19492978
hsa-miR-302d hsa-mir-302d 4 21151097
hsa-miR-302d hsa-mir-302d 4 19280062
hsa-miR-302d hsa-mir-302d 4 18755840
hsa-miR-302d* hsa-mir-302d 4 20676373
hsa-miR-302d* hsa-mir-302d 4 19492978
hsa-miR-302d* hsa-mir-302d 4 21151097
hsa-miR-302d* hsa-mir-302d 4 19280062
hsa-miR-302d* hsa-mir-302d 4 18755840
hsa-miR-302f hsa-mir-302f 0 19492978
hsa-miR-302f hsa-mir-302f 0 21151097
hsa-miR-302f hsa-mir-302f 0 19280062
hsa-miR-302f hsa-mir-302f 0 18755840
hsa-miR-30a hsa-mir-30a 6 20947512
hsa-miR-30a* hsa-mir-30a 6 20947512
hsa-miR-30b hsa-mir-30b 8 20947512
hsa-miR-30b* hsa-mir-30b 8 20947512
hsa-miR-30c hsa-mir-30c-2 6 20947512
hsa-miR-30c hsa-mir-30c-1 1 20947512
hsa-miR-30c-1* hsa-mir-30c-1 1 20947512
hsa-miR-30c-2* hsa-mir-30c-2 6 20947512
hsa-miR-30d hsa-mir-30d 8 20947512
hsa-miR-30d* hsa-mir-30d 8 20947512
hsa-miR-30e hsa-mir-30e 1 20947512
hsa-miR-30e* hsa-mir-30e 1 20947512
hsa-miR-452 hsa-mir-452 X 21211035
hsa-miR-452* hsa-mir-452 X 21211035
hsa-miR-9 hsa-mir-9-1 1 21109969
hsa-miR-9 hsa-mir-9-2 5 21109969
hsa-miR-9 hsa-mir-9-3 15 21109969
hsa-miR-9 hsa-mir-9-1 1 20947512
hsa-miR-9 hsa-mir-9-2 5 20947512
hsa-miR-9 hsa-mir-9-3 15 20947512
hsa-miR-9* hsa-mir-9-1 1 20947512
hsa-miR-92a hsa-mir-92a-1 13 19492978
hsa-miR-92a hsa-mir-92a-2 X 19492978
hsa-miR-93 hsa-mir-93 7 21285944
hsa-miR-93* hsa-mir-93 7 21285944
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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