AutismKB 2.0

Annotation Detail for SOX4


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Basic Information Top
Gene Symbol:SOX4 ( EVI16 )
Gene Full Name: SRY (sex determining region Y)-box 4
Band: 6p22.3
Quick LinksEntrez ID:6659; OMIM: 184430; Uniprot ID:SOX4_HUMAN; ENSEMBL ID: ENSG00000124766; HGNC ID: 11200
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
276Phosphoserine (By similarity).
Location(AA) Modifications Resource
276Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
22Phosphoserine(IKK)HMM predict
33Phosphoserine(CDC2)HMM predict
33O-linkedHMM predict
35Phosphothreonine(CDK)HMM predict
35O-linkedHMM predict
35Phosphothreonine(MAPK)HMM predict
38Phosphoserine(IKK)HMM predict
38O-linkedHMM predict
39O-linkedHMM predict
50Phosphoserine(IKK)HMM predict
54Phosphothreonine(CDC2)HMM predict
140N-linkedHMM predict
142O-linkedHMM predict
148Phosphoserine(PKG)HMM predict
264Phosphothreonine(MAPK)HMM predict
266O-linkedHMM predict
266Phosphoserine(PKB)HMM predict
266Phosphoserine(IKK)HMM predict
268O-linkedHMM predict
272Phosphoserine(IKK)HMM predict
273O-linkedHMM predict
276O-linkedHMM predict
305O-linkedHMM predict
307Phosphoserine(CDC2)HMM predict
333Phosphoserine(ATM)HMM predict
340Phosphoserine(ATM)HMM predict
368Phosphoserine(CDC2)HMM predict
368O-linkedHMM predict
372O-linkedHMM predict
373O-linkedHMM predict
379Phosphoserine(CK2)HMM predict
380O-linkedHMM predict
386Phosphoserine(CK1)HMM predict
386Phosphoserine(IKK)HMM predict
389Phosphoserine(CK1)HMM predict
390Phosphoserine(CK1)HMM predict
396Phosphoserine(CK2)HMM predict
397Phosphoserine(ATM)HMM predict
409N-linkedHMM predict
413N-linkedHMM predict
421Phosphoserine(IKK)HMM predict
449Phosphotyrosine(INSR)HMM predict
459Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003107
  • Location:chr6 21701950-21706825
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 21697465 21697734 269 4351
CTCF CD4SISSRdata 21697465 21697734 269 4351
CTCF G2GSE9613 21695619 21697984 2365 5149
H3K4me3 colorectalcancer 21696508 21697249 741 5072
RARA MCF7GSE15244 21696619 21698113 1494 4585
RARA MCF7GSE15244 21701507 21701945 438 225
Rb SenescentGSE19898 21697020 21697175 155 4853
hScc1 BcellGSE12603 21695515 21696727 1212 5830
hScc1 BcellGSE12603 21697017 21698008 991 4438
hScc1 CdLSGSE12603 21695206 21698113 2907 5291
hScc1 G2GSE9613 21695479 21698113 2634 5155
p130 QuiescentGSE19898 21696966 21697282 316 4827
p130 QuiescentGSE19898 21697478 21697670 192 4377
p130 SenescentGSE19898 21697025 21697292 267 4792
p130 shRbQuiescentGSE19898 21695139 21696044 905 6359
p130 shRbQuiescentGSE19898 21696160 21697746 1586 4998
p130 shRbSenescentGSE19898 21696987 21697265 278 4825
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 21720023 21720086 63 13229
Oct1 HelaGSE14283 21719994 21720087 93 13215
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 21702383 21704069 1686 0
CTCF G2GSE9613 21704832 21705076 244 0
H3K4me3 colorectalcancer 21704380 21704832 452 0
H3ac HepG2E 21701616 21702347 731 0
Myc K562GSE19551 21702958 21703220 262 0
Oct1 HelaGSE14283 21702908 21702967 59 0
Pol2 GM12878GSE19551 21701585 21703233 1648 0
PolII HeLaGSE12783 21701506 21705361 3855 0
hScc1 BcellGSE12603 21702449 21704069 1620 0
hScc1 CdLSGSE12603 21703062 21705618 2556 0
hScc1 G2GSE9613 21701763 21705302 3539 0
p130 QuiescentGSE19898 21701716 21702184 468 0
p130 shRbQuiescentGSE19898 21701828 21702299 471 0
p130 shRbSenescentGSE19898 21701701 21702433 732 0
p130 shRbSenescentGSE19898 21702812 21703154 342 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-10b hsa-mir-10b 2 18373886
hsa-miR-10b* hsa-mir-10b 2 18373886
hsa-miR-126 hsa-mir-126 9 18373886
hsa-miR-126 hsa-mir-126 9 18185580
hsa-miR-126* hsa-mir-126 9 18373886
hsa-miR-126* hsa-mir-126 9 18185580
hsa-miR-129* hsa-mir-129-1 7 19487295
hsa-miR-129-3p hsa-mir-129-2 11 20331975
hsa-miR-129-3p hsa-mir-129-2 11 19887623
hsa-miR-129-3p hsa-mir-129-2 11 19487295
hsa-miR-129-5p hsa-mir-129-1 7 20331975
hsa-miR-129-5p hsa-mir-129-2 11 20331975
hsa-miR-129-5p hsa-mir-129-1 7 19887623
hsa-miR-129-5p hsa-mir-129-2 11 19887623
hsa-miR-129-5p hsa-mir-129-1 7 19487295
hsa-miR-129-5p hsa-mir-129-2 11 19487295
hsa-miR-133b hsa-mir-133b 6 19487295
hsa-miR-145 hsa-mir-145 5 19487295
hsa-miR-145* hsa-mir-145 5 19487295
hsa-miR-206 hsa-mir-206 6 18373886
hsa-miR-21 hsa-mir-21 17 19487295
hsa-miR-21* hsa-mir-21 17 19487295
hsa-miR-335 hsa-mir-335 7 18373886
hsa-miR-335 hsa-mir-335 7 18185580
hsa-miR-335* hsa-mir-335 7 18373886
hsa-miR-335* hsa-mir-335 7 18185580
hsa-miR-373 hsa-mir-373 19 18373886
hsa-miR-373* hsa-mir-373 19 18373886
hsa-miR-518c* hsa-mir-518c 19 19487295
hsa-miR-520c-3p hsa-mir-520c 19 18373886
hsa-miR-520c-5p hsa-mir-520c 19 18373886
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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