AutismKB 2.0

Annotation Detail for SOX5


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Basic Information Top
Gene Symbol:SOX5 ( L-SOX5,MGC35153 )
Gene Full Name: SRY (sex determining region Y)-box 5
Band: 12p12.1
Quick LinksEntrez ID:6660; OMIM: 604975; Uniprot ID:SOX5_HUMAN; ENSEMBL ID: ENSG00000134532; HGNC ID: 11201
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
108Phosphothreonine (By similarity).
414Phosphoserine (By similarity).
Location(AA) Modifications Resource
108Phosphothreonine (By similarity).Swiss-Prot 53.0
414Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
21Phosphoserine(CDC2)HMM predict
44Phosphoserine(CK1)HMM predict
71Phosphoserine(IKK)HMM predict
82Phosphothreonine(MAPK)HMM predict
82Phosphothreonine(CDK)HMM predict
82PhosphothreonineHMM predict
84PhosphothreonineHMM predict
105N-linkedHMM predict
109Phosphoserine(CDK)HMM predict
109Phosphoserine(CDC2)HMM predict
131Phosphothreonine(CDC2)HMM predict
131Phosphothreonine(CDK)HMM predict
131Phosphothreonine(MAPK)HMM predict
138Phosphoserine(PKC)HMM predict
138Phosphoserine(PKG)HMM predict
162Phosphothreonine(MAPK)HMM predict
311Phosphoserine(ATM)HMM predict
330Phosphothreonine(MAPK)HMM predict
372O-linkedHMM predict
376O-linkedHMM predict
382Phosphoserine(CDK)HMM predict
382Phosphoserine(CDC2)HMM predict
382Phosphoserine(PKA)HMM predict
382Phosphoserine(MAPK)HMM predict
408Phosphoserine(IKK)HMM predict
408Phosphoserine(CDC2)HMM predict
410O-linkedHMM predict
410O-linkedHMM predict
411Phosphoserine(IKK)HMM predict
411Phosphoserine(MAPK)HMM predict
411Phosphoserine(CDC2)HMM predict
411O-linkedHMM predict
414O-linkedHMM predict
439Phosphoserine(MAPK)HMM predict
441O-linkedHMM predict
441O-linkedHMM predict
445Phosphoserine(PKG)HMM predict
526N-linkedHMM predict
528Phosphoserine(CK2)HMM predict
543Phosphotyrosine(EGFR)HMM predict
547MethylarginineHMM predict
605Phosphotyrosine(Syk)HMM predict
696Phosphoserine(CK1)HMM predict
696Phosphoserine(IKK)HMM predict
697Phosphoserine(ATM)HMM predict
699Phosphoserine(CK2)HMM predict
700Phosphoserine(CK1)HMM predict
701Phosphoserine(CDK)HMM predict
701Phosphoserine(ATM)HMM predict
701Phosphoserine(CDC2)HMM predict
736Phosphotyrosine(INSR)HMM predict
736SulfotyrosineHMM predict
750SulfotyrosineHMM predict
760GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006940
  • Location:chr12 23576498-23993903
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 23836820 23837050 230 0
ER E2-MCF7GSE14664 23832881 23832917 36 0
FOXA1 DLD1GSE12801 23979828 23980335 507 0
Gata2 K562GSE18868 23929110 23929460 350 0
H3K27me3 colorectalcancer 23993175 23994039 864 0
H3ac HepG2E 23986404 23988442 2038 0
Myc K562GSE19551 23929224 23929429 205 0
Nanog ESGSE20650 23710914 23711324 410 0
Nanog ESGSE20650 23860537 23861202 665 0
Nanog hESGSE18292 23673181 23673619 438 0
Nanog hESGSE18292 23784376 23784944 568 0
Oct1 H2O2-HelaGSE14283 23844956 23844983 27 0
Oct1 HelaGSE14283 23631872 23631907 35 0
Oct1 HelaGSE14283 23755842 23755877 35 0
Oct4 ESGSE20650 23860637 23861097 460 0
Oct4 hESGSE17917 23629989 23630269 280 0
Oct4 hESGSE21916 23629955 23630370 415 0
PAX3-FKHR Rh4GSE19063 23795286 23796940 1654 0
TFAP2C MCF7GSE21234 23801792 23802110 318 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-21 hsa-mir-21 17 19013014
hsa-miR-21* hsa-mir-21 17 19013014
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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