AutismKB 2.0

Annotation Detail for SOX10


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Basic Information Top
Gene Symbol:SOX10 ( DOM,MGC15649,PCWH,WS2E,WS4,WS4C )
Gene Full Name: SRY (sex determining region Y)-box 10
Band: 22q13.1
Quick LinksEntrez ID:6663; OMIM: 602229; Uniprot ID:SOX10_HUMAN; ENSEMBL ID: ENSG00000100146; HGNC ID: 11190
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
24Phosphoserine.
45Phosphoserine.
145Nuclear export signal.
Location(AA) Modifications Resource
Location(AA) Modification Resource
8Phosphoserine(CK2)HMM predict
13Phosphoserine(IKK)HMM predict
13Phosphoserine(CDC2)HMM predict
24Phosphoserine(CDC2)HMM predict
30O-linkedHMM predict
43MethylarginineHMM predict
45Phosphoserine(CDC2)HMM predict
171SulfotyrosineHMM predict
240Phosphothreonine(MAPK)HMM predict
240O-linkedHMM predict
244Phosphothreonine(MAPK)HMM predict
244O-linkedHMM predict
244O-linkedHMM predict
300Phosphotyrosine(INSR)HMM predict
344Phosphothreonine(PKC)HMM predict
346O-linkedHMM predict
402SulfotyrosineHMM predict
403Phosphoserine(ATM)HMM predict
412SulfotyrosineHMM predict
436Phosphotyrosine(Jak)HMM predict
443Phosphoserine(IKK)HMM predict
443O-linkedHMM predict
445Phosphoserine(ATM)HMM predict
445Phosphoserine(CK1)HMM predict
445O-linkedHMM predict
460Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006941
  • Location:chr22 36698265-36710484
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 36725147 36726266 1119 15222
TFAP2C MCF7GSE21234 36721962 36722435 473 11714
TFAP2C MCF7GSE21234 36725253 36726113 860 15199
hScc1 CdLSGSE12603 36721978 36722221 243 11615
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018