AutismKB 2.0

Annotation Detail for SPAM1


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Basic Information Top
Gene Symbol:SPAM1 ( HYA1,HYAL1,HYAL3,HYAL5,MGC26532,PH-20,PH20,SPAG15 )
Gene Full Name: sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
Band: 7q31
Quick LinksEntrez ID:6677; OMIM: 600930; Uniprot ID:HYALP_HUMAN; ENSEMBL ID: ENSG00000106304; HGNC ID: 11217
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
82N-linked (GlcNAc...) (Potential).
166N-linked (GlcNAc...) (Potential).
235N-linked (GlcNAc...) (Potential).
254N-linked (GlcNAc...) (Potential).
368N-linked (GlcNAc...) (Potential).
393N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
82N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
166N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
235N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
254N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
368N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
393N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
490GPI-anchor amidated serine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
32S-palmitoylHMM predict
33S-palmitoylHMM predict
78Phosphoserine(CDC2)HMM predict
82N-linkedHMM predict
134Phosphotyrosine(Syk)HMM predict
164Phosphotyrosine(Syk)HMM predict
229Phosphotyrosine(Syk)HMM predict
235N-linkedHMM predict
240N-linkedHMM predict
264Phosphotyrosine(Syk)HMM predict
270Phosphoserine(CDK)HMM predict
296Phosphoserine(CDC2)HMM predict
368N-linkedHMM predict
393N-linkedHMM predict
416Phosphothreonine(PKC)HMM predict
483N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003117
  • Location:chr7 123352564-123398694
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 CdLSGSE12603 123394227 123394456 229 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018