AutismKB 2.0

Annotation Detail for SPI1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SPI1 ( OF,PU.1,SFPI1,SPI-1,SPI-A )
Gene Full Name: spleen focus forming virus (SFFV) proviral integration oncogene spi1
Band: 11p11.2
Quick LinksEntrez ID:6688; OMIM: 165170; Uniprot ID:SPI1_HUMAN; ENSEMBL ID: ENSG00000066336; HGNC ID: 11241
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
146Phosphoserine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
35SulfotyrosineHMM predict
35Phosphotyrosine(Syk)HMM predict
36SulfotyrosineHMM predict
64Phosphoserine(IKK)HMM predict
64Phosphoserine(CK2)HMM predict
69N-linkedHMM predict
125Phosphoserine(CDC2)HMM predict
125O-linkedHMM predict
131Phosphoserine(ATM)HMM predict
131Phosphoserine(CK2)HMM predict
131PhosphoserineHMM predict
131Phosphoserine(CK2)HMM predict
225Phosphotyrosine(INSR)HMM predict
249Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003120
  • Location:chr11 47332987-47356673
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 47360549 47360872 323 4037
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 47337127 47338853 1726 0
CTCF CD4GSE12889 47352090 47352432 342 0
CTCF CD4SISSRdata 47352090 47352432 342 0
CTCF HelaGSE12889 47333395 47333671 276 0
CTCF HelaGSE12889 47352057 47352475 418 0
CTCF JurkatGSE12889 47333401 47333653 252 0
CTCF JurkatGSE12889 47352121 47352302 181 0
FoxA1 MCF7MACSdata 47346623 47346742 119 0
NRSF pAbJurkat 47354062 47354615 553 0
P300 T30-glioblastomaGSE21026 47333282 47333954 672 0
RARA MCF7GSE15244 47351793 47352041 248 0
RARG MCF7GSE15244 47351793 47352111 318 0
Rb GrowingGSE19898 47339700 47339851 151 0
Rb QuiescentGSE19898 47352176 47352395 219 0
TAF HelaGSE8489 47353510 47353749 239 0
hScc1 BcellGSE12603 47333369 47333555 186 0
hScc1 BcellGSE12603 47351793 47352712 919 0
hScc1 CdLSGSE12603 47352041 47352491 450 0
hScc1 G2GSE9613 47333031 47333773 742 0
hScc1 G2GSE9613 47351793 47352226 433 0
p130 SenescentGSE19898 47333396 47333566 170 0
p130 SenescentGSE19898 47354515 47354726 211 0
p130 shRbSenescentGSE19898 47333385 47333630 245 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-143 hsa-mir-143 5 21211043
hsa-miR-143* hsa-mir-143 5 21211043
hsa-miR-145 hsa-mir-145 5 21211043
hsa-miR-145* hsa-mir-145 5 21211043
hsa-miR-146a hsa-mir-146a 5 21211043
hsa-miR-146a* hsa-mir-146a 5 21211043
hsa-miR-155 hsa-mir-155 21 20947507
hsa-miR-155* hsa-mir-155 21 20947507
hsa-miR-17 hsa-mir-17 13 17586726
hsa-miR-17* hsa-mir-17 13 17586726
hsa-miR-23a hsa-mir-23a 19 20399246
hsa-miR-23a* hsa-mir-23a 19 20399246
hsa-miR-24 hsa-mir-24-2 19 20399246
hsa-miR-24-2* hsa-mir-24-2 19 20399246
hsa-miR-27a hsa-mir-27a 19 20399246
hsa-miR-27a* hsa-mir-27a 19 20399246
hsa-miR-34a hsa-mir-34a 1 21211043
hsa-miR-34a* hsa-mir-34a 1 21211043
hsa-miR-378 hsa-mir-378 5 21211043
hsa-miR-378* hsa-mir-378 5 21211043
hsa-miR-569 hsa-mir-569 3 21360505
hsa-miR-569 hsa-mir-569 3 21162035
hsa-miR-92a hsa-mir-92a-1 13 17586726
hsa-miR-92a hsa-mir-92a-2 X 17586726
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4398 mRNA SLC39A13 chr11 47333576 47394620 71 mRNA SPI1 chr11 47332987 47356674Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved