AutismKB 2.0

Annotation Detail for SQLE


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Basic Information Top
Gene Symbol:SQLE ( FLJ30795 )
Gene Full Name: squalene epoxidase
Band: 8q24.13
Quick LinksEntrez ID:6713; OMIM: 602019; Uniprot ID:ERG1_HUMAN; ENSEMBL ID: ENSG00000104549; HGNC ID: 11279
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
59Phosphoserine(CAMK2)HMM predict
61Phosphoserine(ATM)HMM predict
83Phosphoserine(CDC2)HMM predict
102Phosphothreonine(PKA)HMM predict
103N-linkedHMM predict
108O-linkedHMM predict
112O-linkedHMM predict
116O-linkedHMM predict
117Phosphoserine(IKK)HMM predict
118O-linkedHMM predict
120Phosphoserine(IKK)HMM predict
120Phosphoserine(ATM)HMM predict
150Phosphothreonine(PKA)HMM predict
150Phosphothreonine(PKC)HMM predict
202Phosphoserine(CK1)HMM predict
204Phosphoserine(CK1)HMM predict
328N-linkedHMM predict
359Phosphotyrosine(INSR)HMM predict
365Phosphotyrosine(EGFR)HMM predict
396Phosphoserine(CDC2)HMM predict
422Phosphothreonine(PKC)HMM predict
513Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003129
  • Location:chr8 126079900-126103704
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 126078979 126079397 418 713
Fos K562GSE19551 126079444 126080123 679 117
H3ac HepG2E 126078006 126079431 1425 1182
PHF8 HeLaGSE20725 126079038 126080665 1627 49
hScc1 BcellGSE12603 126079081 126080636 1555 42
hScc1 CdLSGSE12603 126079431 126080239 808 66
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 126103988 126104015 27 297
Oct1 HelaGSE14283 126103985 126104021 36 299
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 126080318 126080986 668 0
FOXA1 MCF7GSE15244 126090201 126090869 668 0
FOXA1 MCF7GSE15244 126101029 126101172 143 0
H3ac HepG2E 126080318 126081807 1489 0
H3ac HepG2E 126082226 126083484 1258 0
Oct1 H2O2-HelaGSE14283 126082208 126082238 30 0
Oct1 H2O2-HelaGSE14283 126093121 126093159 38 0
Oct1 HelaGSE14283 126093127 126093158 31 0
Oct1 HelaGSE14283 126101028 126101117 89 0
RARG MCF7GSE15244 126080365 126080986 621 0
p130 SenescentGSE19898 126082205 126082558 353 0
p130 shRbQuiescentGSE19898 126079981 126080408 427 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018