AutismKB 2.0

Annotation Detail for SRMS


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Basic Information Top
Gene Symbol:SRMS ( C20orf148,SRM,dJ697K14.1 )
Gene Full Name: src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
Band: 20q13.33
Quick LinksEntrez ID:6725; OMIM: NA; Uniprot ID:SRMS_HUMAN; ENSEMBL ID: ENSG00000125508; HGNC ID: 11298
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
261N6-acetyllysine (By similarity).
380Phosphotyrosine; by autocatalysis (By
Location(AA) Modifications Resource
261N6-acetyllysine (By similarity).Swiss-Prot 53.0
380Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
30Phosphothreonine(CDK)HMM predict
50Phosphoserine(MAPK)HMM predict
94Phosphoserine(PKA)HMM predict
94Phosphoserine(PKG)HMM predict
136Phosphoserine(MAPK)HMM predict
136Phosphoserine(CDC2)HMM predict
149Phosphoserine(PKA)HMM predict
152Phosphoserine(CK1)HMM predict
299Phosphotyrosine(SRC)HMM predict
299Phosphotyrosine(EGFR)HMM predict
380Phosphotyrosine(INSR)HMM predict
381Phosphoserine(MAPK)HMM predict
384Phosphoserine(CDC2)HMM predict
385Phosphoserine(CK1)HMM predict
404Phosphoserine(PKC)HMM predict
427Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_080823
  • Location:chr20 61642606-61649300
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 61649560 61650065 505 512
hScc1 BcellGSE12603 61649168 61649558 390 63
hScc1 BcellGSE12603 61650034 61650904 870 1169
hScc1 BcellGSE12603 61651413 61652053 640 2433
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 61640896 61643121 2225 598
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 61643757 61645315 1558 0
TFAP2C MCF7GSE21234 61646263 61648007 1744 0
hScc1 BcellGSE12603 61643574 61643879 305 0
hScc1 BcellGSE12603 61644903 61645278 375 0
hScc1 BcellGSE12603 61646051 61646660 609 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018