AutismKB 2.0

Annotation Detail for BRAF


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:BRAF ( B-RAF1,BRAF1,FLJ95109,MGC126806,MGC138284,RAFB1 )
Gene Full Name: v-raf murine sarcoma viral oncogene homolog B1
Band: 7q34
Quick LinksEntrez ID:673; OMIM: 164757; Uniprot ID:BRAF_HUMAN; ENSEMBL ID: ENSG00000157764; HGNC ID: 1097
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
151Phosphoserine.
365Phosphoserine.
373Phosphothreonine; by autocatalysis.
396Phosphothreonine.
399Phosphoserine.
401Phosphothreonine.
418N6-acetyllysine.
419Phosphoserine.
446Phosphoserine.
447Phosphoserine.
465Phosphoserine.
614Phosphoserine.
729Phosphoserine.
750Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004333
  • Location:chr7 140080753-140271032
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 140272277 140272421 144 1317
Oct1 HelaGSE14283 140288139 140288168 29 17121
Rb SenescentGSE19898 140271212 140271677 465 412
p130 QuiescentGSE19898 140271135 140271453 318 262
p130 SenescentGSE19898 140271220 140271556 336 356
p130 shRbQuiescentGSE19898 140271137 140271771 634 422
p130 shRbSenescentGSE19898 140271221 140271689 468 423
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 140072042 140072588 546 8439
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 140157322 140157635 313 0
CTCF CD4SISSRdata 140157322 140157635 313 0
CTCF G2GSE9613 140219751 140219997 246 0
CTCF G2GSE9613 140270104 140270984 880 0
ER E2-MCF7GSE14664 140161904 140161939 35 0
ER E2-MCF7GSE14664 140239689 140239721 32 0
FOXA1 MCF7GSE15244 140259120 140259713 593 0
Fos K562GSE19551 140087639 140088053 414 0
FoxA1 MCF7MACSdata 140259408 140259637 229 0
H3K4me2 HCT116GSE10453 140269691 140270450 759 0
H3K4me3 colorectalcancer 140269727 140270566 839 0
H3ac HepG2E 140269691 140270635 944 0
Myc K562GSE19551 140157306 140157666 360 0
Oct1 HelaGSE14283 140104013 140104075 62 0
Oct1 HelaGSE14283 140193515 140193546 31 0
PHF8 HeLaGSE20725 140270257 140271700 1443 0
TAF HelaGSE8489 140268793 140270490 1697 0
TAF k562GSE8489 140268972 140270490 1518 0
hScc1 BcellGSE12603 140270033 140271233 1200 0
hScc1 CdLSGSE12603 140269887 140270806 919 0
p63 keratinocytesGSE17611 140213843 140214641 798 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20177422
hsa-let-7a hsa-let-7a-2 11 20177422
hsa-let-7a hsa-let-7a-3 22 20177422
hsa-let-7a* hsa-let-7a-1 9 20177422
hsa-let-7a* hsa-let-7a-3 22 20177422
hsa-let-7b hsa-let-7b 22 20177422
hsa-let-7b* hsa-let-7b 22 20177422
hsa-let-7c hsa-let-7c 21 20177422
hsa-let-7c* hsa-let-7c 21 20177422
hsa-let-7d hsa-let-7d 9 20177422
hsa-let-7d* hsa-let-7d 9 20177422
hsa-let-7e hsa-let-7e 19 20177422
hsa-let-7e* hsa-let-7e 19 20177422
hsa-let-7f hsa-let-7f-1 9 20177422
hsa-let-7f hsa-let-7f-2 X 20177422
hsa-let-7f-1* hsa-let-7f-1 9 20177422
hsa-let-7f-2* hsa-let-7f-2 X 20177422
hsa-let-7g hsa-let-7g 3 20177422
hsa-let-7g* hsa-let-7g 3 20177422
hsa-let-7i hsa-let-7i 12 20177422
hsa-let-7i* hsa-let-7i 12 20177422
hsa-miR-146b-3p hsa-mir-146b 10 19370505
hsa-miR-146b-3p hsa-mir-146b 10 20406109
hsa-miR-146b-3p hsa-mir-146b 10 20459574
hsa-miR-146b-5p hsa-mir-146b 10 19370505
hsa-miR-146b-5p hsa-mir-146b 10 20406109
hsa-miR-146b-5p hsa-mir-146b 10 20459574
hsa-miR-183 hsa-mir-183 7 19047896
hsa-miR-183* hsa-mir-183 7 19047896
hsa-miR-191 hsa-mir-191 3 20357817
hsa-miR-191* hsa-mir-191 3 20357817
hsa-miR-192 hsa-mir-192 11 19047896
hsa-miR-192* hsa-mir-192 11 19047896
hsa-miR-193a-3p hsa-mir-193a 17 20357817
hsa-miR-193a-5p hsa-mir-193a 17 20357817
hsa-miR-193b hsa-mir-193b 16 20357817
hsa-miR-193b* hsa-mir-193b 16 20357817
hsa-miR-338-3p hsa-mir-338 17 20357817
hsa-miR-338-5p hsa-mir-338 17 20357817
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved