AutismKB 2.0

Annotation Detail for SRPK2


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Basic Information Top
Gene Symbol:SRPK2 ( FLJ36101,SFRSK2 )
Gene Full Name: SRSF protein kinase 2
Band: 7q22.3
Quick LinksEntrez ID:6733; OMIM: 602980; Uniprot ID:SRPK2_HUMAN; ENSEMBL ID: ENSG00000135250; HGNC ID: 11306
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
52Phosphoserine; by CK2 (By similarity).
319Phosphotyrosine.
380Phosphoserine.
494Phosphoserine.
497Phosphoserine.
498Phosphothreonine.
547Phosphothreonine.
588Phosphoserine; by CK2 (By similarity).
Location(AA) Modifications Resource
52Phosphoserine (by CK2) (By similarity).Swiss-Prot 53.0
319Phosphotyrosine.Swiss-Prot 53.0
319PhosphotyrosinePhospho.ELM 6.0
494PhosphoserinePhospho.ELM 6.0
498PhosphothreoninePhospho.ELM 6.0
588Phosphoserine (by CK2) (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
10Phosphoserine(CK1)HMM predict
10Phosphoserine(CDC2)HMM predict
11Phosphoserine(CK2)HMM predict
11O-linkedHMM predict
52Phosphoserine(CK2)HMM predict
203Phosphotyrosine(Jak)HMM predict
248O-linkedHMM predict
248O-linkedHMM predict
248O-linkedHMM predict
250O-linkedHMM predict
250O-linkedHMM predict
253O-linkedHMM predict
305N-linkedHMM predict
427SulfotyrosineHMM predict
448Phosphoserine(ATM)HMM predict
483Phosphoserine(CK1)HMM predict
484Phosphoserine(CK1)HMM predict
484PhosphoserineHMM predict
484Phosphoserine(ATM)HMM predict
492Phosphothreonine(PKC)HMM predict
494Phosphoserine(PKB)HMM predict
494Phosphoserine(IKK)HMM predict
494O-linkedHMM predict
494Phosphoserine(CAMK2)HMM predict
592Phosphotyrosine(INSR)HMM predict
592SulfotyrosineHMM predict
593Phosphoserine(CK2)HMM predict
679S-farnesylHMM predict
681S-palmitoylHMM predict
682ArginineHMM predict
684ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_182691
  • Location:chr7 104544059-104696712
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 104580700 104580839 139 0
CTCF CD4SISSRdata 104580700 104580839 139 0
CTCF G2GSE9613 104564737 104565155 418 0
CTCF G2GSE9613 104658013 104658166 153 0
CTCF G2GSE9613 104672272 104672459 187 0
ER MCF7GSE19013 104689458 104689913 455 0
Fos K562GSE19551 104652801 104653284 483 0
FoxA1 MCF7MACSdata 104685137 104685373 236 0
GABP k562GSE8489 104605745 104606190 445 0
NRSF mAbJurkat 104626211 104626751 540 0
Oct1 H2O2-HelaGSE14283 104622971 104622999 28 0
Oct1 H2O2-HelaGSE14283 104637181 104637212 31 0
Oct1 H2O2-HelaGSE14283 104655720 104655765 45 0
Oct1 HelaGSE14283 104571547 104571622 75 0
Oct1 HelaGSE14283 104622971 104622999 28 0
Oct1 HelaGSE14283 104635003 104635041 38 0
Oct1 HelaGSE14283 104637181 104637239 58 0
Oct1 HelaGSE14283 104655720 104655764 44 0
Oct1 HelaGSE14283 104695716 104695781 65 0
P300 T30-glioblastomaGSE21026 104625595 104626504 909 0
P300 T30-glioblastomaGSE21026 104652641 104653418 777 0
PolII HeLaGSE12783 104696232 104697025 793 0
Rb GrowingGSE19898 104646727 104646920 193 0
TFAP2C MCF7GSE21234 104632063 104632562 499 0
hScc1 BcellGSE12603 104568705 104569065 360 0
hScc1 BcellGSE12603 104580731 104580913 182 0
hScc1 CdLSGSE12603 104580731 104581119 388 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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