AutismKB 2.0

Annotation Detail for SRPR


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Basic Information Top
Gene Symbol:SRPR ( DP,MGC17355,MGC3650,MGC9571,Sralpha )
Gene Full Name: signal recognition particle receptor (docking protein)
Band: 11q24.2
Quick LinksEntrez ID:6734; OMIM: 182180; Uniprot ID:SRPR_HUMAN; ENSEMBL ID: ENSG00000182934; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
261Phosphotyrosine.
296Phosphoserine.
297Phosphoserine.
298Phosphoserine.
Location(AA) Modifications Resource
261Phosphotyrosine.Swiss-Prot 53.0
261PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
24Phosphoserine(IKK)HMM predict
44N-linkedHMM predict
45N-linkedHMM predict
53Phosphothreonine(PKC)HMM predict
105Phosphoserine(CK1)HMM predict
108N-linkedHMM predict
128Phosphoserine(CK1)HMM predict
134Phosphothreonine(PKC)HMM predict
142Phosphoserine(CK2)HMM predict
167Phosphoserine(PKG)HMM predict
183O-linkedHMM predict
183O-linkedHMM predict
183Phosphothreonine(PKC)HMM predict
229N-linkedHMM predict
232Phosphothreonine(CK2)HMM predict
267N-linkedHMM predict
269O-linkedHMM predict
297Phosphoserine(CK1)HMM predict
297Phosphoserine(CK2)HMM predict
298Phosphoserine(CK2)HMM predict
306N-linkedHMM predict
382O-linkedHMM predict
383O-linkedHMM predict
473Phosphoserine(PKG)HMM predict
574Phosphoserine(IKK)HMM predict
620TyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003139
  • Location:chr11 125638049-125643959
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 125643383 125644554 1171 9
FOXA1 MCF7GSE15244 125643485 125644481 996 24
PHF8 293TGSE20725 125643385 125644803 1418 135
Rb SenescentGSE19898 125643553 125644597 1044 116
USF1 HepG2E 125643255 125644773 1518 55
USF2 HepG2E 125643291 125644773 1482 73
p130 QuiescentGSE19898 125643665 125644444 779 95
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 125642581 125643706 1125 0
H3ac HepG2E 125640808 125641838 1030 0
H3ac HepG2E 125642183 125643887 1704 0
Rb QuiescentGSE19898 125643675 125644128 453 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1103 Unknown pSILAC miR-16 SRPR down 75-50% 18668040
1104 Unknown pSILAC miR-16 SRPR down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000182934 n_a n_a n_a n_a n_a
ENSG00000182934 n_a n_a n_a n_a n_a
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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