AutismKB 2.0

Annotation Detail for SSB


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Basic Information Top
Gene Symbol:SSB ( LARP3,La )
Gene Full Name: Sjogren syndrome antigen B (autoantigen La)
Band: 2q31.1
Quick LinksEntrez ID:6741; OMIM: 109090; Uniprot ID:LA_HUMAN; ENSEMBL ID: ENSG00000138385; HGNC ID: 11316
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
116N6-acetyllysine.
128N6-acetyllysine.
328N6-acetyllysine.
360N6-acetyllysine.
362Phosphothreonine.
366Phosphoserine; by CK2.
Location(AA) Modifications Resource
302PhosphothreoninePhospho.ELM 6.0
325PhosphoserinePhospho.ELM 6.0
362PhosphothreoninePhospho.ELM 6.0
366Phosphoserine (by CK2).Swiss-Prot 53.0
366Phosphoserine (CK2
Location(AA) Modification Resource
92Phosphoserine(CDC2)HMM predict
92Phosphoserine(CDK)HMM predict
94Phosphoserine(PKA)HMM predict
94Phosphoserine(IKK)HMM predict
366Phosphoserine(CK2)HMM predict
389Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003142
  • Location:chr2 170363634-170376814
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 170354390 170355150 760 8865
Oct4 ESGSE20650 170354453 170354988 535 8914
Oct4 hESGSE21916 170354428 170355113 685 8864
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 170364215 170364848 633 0
H3K4me3 colorectalcancer 170364245 170364781 536 0
H3ac HepG2E 170364096 170364979 883 0
Oct1 HelaGSE14283 170372228 170372265 37 0
PHF8 293TGSE20725 170363258 170364415 1157 0
PHF8 HeLaGSE20725 170363271 170364230 959 0
TAF k562GSE8489 170364069 170364979 910 0
p130 QuiescentGSE19898 170363555 170363881 326 0
p130 shRbSenescentGSE19898 170363589 170363826 237 0
p130 shRbSenescentGSE19898 170364118 170364355 237 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15252 mRNA SSB chr2 170480895 170494082 62 mRNA METTL5 chr2 170492097 170506922Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018