AutismKB 2.0

Annotation Detail for STAT2


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Basic Information Top
Gene Symbol:STAT2 ( ISGF-3,MGC59816,P113,STAT113 )
Gene Full Name: signal transducer and activator of transcription 2, 113kDa
Band: 12q13.2
Quick LinksEntrez ID:6773; OMIM: 600556; Uniprot ID:STAT2_HUMAN; ENSEMBL ID: ENSG00000170581; HGNC ID: 11363
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
375N6-acetyllysine.
595Phosphoserine.
690Phosphotyrosine; by JAK (By similarity).
Location(AA) Modifications Resource
690Phosphotyrosine (by JAK) (By similarity).Swiss-Prot 53.0
690Phosphotyrosine (JAK
Location(AA) Modification Resource
54Phosphoserine(IKK)HMM predict
98Phosphoserine(ATM)HMM predict
136Phosphothreonine(CDK)HMM predict
140Phosphoserine(ATM)HMM predict
327Phosphothreonine(CDC2)HMM predict
341Phosphothreonine(PKC)HMM predict
354N-linkedHMM predict
387Phosphothreonine(CDC2)HMM predict
387Phosphothreonine(CDK)HMM predict
393Phosphoserine(ATM)HMM predict
476Phosphoserine(MAPK)HMM predict
494Phosphoserine(IKK)HMM predict
690Phosphotyrosine(Jak)HMM predict
734Phosphoserine(CK1)HMM predict
783Phosphoserine(ATM)HMM predict
828Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005419
  • Location:chr12 55021650-55040175
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 55039932 55040548 616 65
Fos K562GSE19551 55039934 55040731 797 157
Rb GrowingGSE19898 55040123 55040573 450 173
Rb SenescentGSE19898 55039951 55040603 652 102
hScc1 BcellGSE12603 55039968 55040525 557 71
hScc1 CdLSGSE12603 55039932 55040525 593 53
p130 QuiescentGSE19898 55039947 55040617 670 107
p130 shRbSenescentGSE19898 55039790 55040646 856 43
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 55026853 55026976 123 0
CTCF CD4SISSRdata 55026853 55026976 123 0
CTCF HelaGSE12889 55026762 55027016 254 0
CTCF G2GSE9613 55026607 55027060 453 0
FOXA1 MCF7GSE15244 55026533 55026881 348 0
FOXA1 MCF7GSE15244 55039824 55040414 590 0
H3K4me2 HCT116GSE10453 55039481 55039785 304 0
H3K4me3 colorectalcancer 55039481 55039824 343 0
H3ac HepG2E 55039192 55040173 981 0
NRSF pAbJurkat 55028966 55029348 382 0
Oct1 H2O2-HelaGSE14283 55037303 55037358 55 0
Oct1 HelaGSE14283 55037309 55037362 53 0
PHF8 HeLaGSE20725 55039884 55040294 410 0
TAF HelaGSE8489 55039481 55039862 381 0
p130 QuiescentGSE19898 55039150 55039364 214 0
p130 SenescentGSE19898 55039792 55040247 455 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-221 hsa-mir-221 X 20428775
hsa-miR-221* hsa-mir-221 X 20428775
hsa-miR-222 hsa-mir-222 X 20428775
hsa-miR-222* hsa-mir-222 X 20428775
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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