AutismKB 2.0

Annotation Detail for STAT5A


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Basic Information Top
Gene Symbol:STAT5A ( MGF,STAT5 )
Gene Full Name: signal transducer and activator of transcription 5A
Band: 17q21.2
Quick LinksEntrez ID:6776; OMIM: 601511; Uniprot ID:STA5A_HUMAN; ENSEMBL ID: ENSG00000126561; HGNC ID: 11366
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
193Phosphoserine.
372Phosphothreonine.
375Phosphoserine.
694Phosphotyrosine; by JAK.
780Phosphoserine (By similarity).
Location(AA) Modifications Resource
90PhosphotyrosinePhospho.ELM 6.0
694Phosphotyrosine (by JAK).Swiss-Prot 53.0
694Phosphotyrosine (Lyn;Src;JAK2)Phospho.ELM 6.0
780Phosphoserine (By similarity).Swiss-Prot 53.0
780Phosphoserine (MAPK1;MAPK3)Phospho.ELM 6.0
Location(AA) Modification Resource
40Phosphoserine(ATM)HMM predict
125N-linkedHMM predict
128Phosphoserine(CDC2)HMM predict
145N-linkedHMM predict
158Phosphothreonine(CK2)HMM predict
199Phosphoserine(CK1)HMM predict
317N-linkedHMM predict
325O-linkedHMM predict
434Phosphoserine(PKG)HMM predict
473Phosphoserine(ATM)HMM predict
477N-linkedHMM predict
539N-linkedHMM predict
540N-linkedHMM predict
542Phosphoserine(CK2)HMM predict
548Phosphotyrosine(INSR)HMM predict
567N-linkedHMM predict
635Phosphoserine(CDC2)HMM predict
635Phosphoserine(CDC2)HMM predict
652Phosphoserine(CAMK2)HMM predict
694Phosphotyrosine(Jak)HMM predict
720Phosphotyrosine(INSR)HMM predict
720Phosphotyrosine(Syk)HMM predict
735Phosphotyrosine(Syk)HMM predict
780Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003152
  • Location:chr17 37693090-37717483
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 37691799 37692108 309 1137
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 37717770 37718085 315 444
CTCF CD4SISSRdata 37717770 37718085 315 444
CTCF G2GSE9613 37717809 37718111 302 477
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37693698 37694392 694 0
CTCF G2GSE9613 37697287 37697703 416 0
CTCF G2GSE9613 37706200 37706526 326 0
CTCF G2GSE9613 37711075 37711503 428 0
H3ac HepG2E 37710221 37710433 212 0
NFkBII GM12878GSE19485 37692244 37696304 4060 0
NFkBII GM18526GSE19485 37692659 37694370 1711 0
Oct1 HelaGSE14283 37699070 37699104 34 0
Rb SenescentGSE19898 37693752 37694026 274 0
TAF k562GSE8489 37695367 37696183 816 0
hScc1 BcellGSE12603 37693493 37694311 818 0
hScc1 BcellGSE12603 37706337 37706860 523 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-126 hsa-mir-126 9 20489169
hsa-miR-126* hsa-mir-126 9 20489169
hsa-miR-151-3p hsa-mir-151 8 20445018
hsa-miR-151-5p hsa-mir-151 8 20445018
hsa-miR-155 hsa-mir-155 21 19144316
hsa-miR-155 hsa-mir-155 21 19109256
hsa-miR-155* hsa-mir-155 21 19144316
hsa-miR-155* hsa-mir-155 21 19109256
hsa-miR-15a hsa-mir-15a 13 19109256
hsa-miR-15a* hsa-mir-15a 13 19109256
hsa-miR-16 hsa-mir-16-1 13 20008792
hsa-miR-16 hsa-mir-16-2 3 20008792
hsa-miR-21 hsa-mir-21 17 20489169
hsa-miR-21* hsa-mir-21 17 20489169
hsa-miR-210 hsa-mir-210 11 20489169
hsa-miR-221 hsa-mir-221 X 20489169
hsa-miR-221* hsa-mir-221 X 20489169
hsa-miR-222 hsa-mir-222 X 20489169
hsa-miR-222* hsa-mir-222 X 20489169
hsa-miR-28-3p hsa-mir-28 3 20445018
hsa-miR-28-5p hsa-mir-28 3 20445018
hsa-miR-296-3p hsa-mir-296 20 20489169
hsa-miR-296-5p hsa-mir-296 20 20489169
hsa-miR-708 hsa-mir-708 11 20445018
hsa-miR-708* hsa-mir-708 11 20445018
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018