AutismKB 2.0

Annotation Detail for SUPT6H


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SUPT6H ( KIAA0162,MGC87943,SPT6,SPT6H,emb-5 )
Gene Full Name: suppressor of Ty 6 homolog (S. cerevisiae)
Band: 17q11.2
Quick LinksEntrez ID:6830; OMIM: 601333; Uniprot ID:SPT6H_HUMAN; ENSEMBL ID: ENSG00000109111; HGNC ID: 11470
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
7Phosphoserine.
12Phosphoserine.
73Phosphoserine.
75Phosphoserine.
78Phosphoserine.
125Phosphoserine.
179Phosphoserine.
267Phosphoserine.
743N6-acetyllysine.
1523Phosphothreonine.
1526Phosphoserine.
1532Phosphothreonine.
1535Phosphoserine.
1539Phosphothreonine.
1676N6-acetyllysine.
1697Phosphothreonine.
1701Phosphoserine.
1703Phosphoserine.
1718Phosphothreonine.
Location(AA) Modifications Resource
73Phosphoserine.Swiss-Prot 53.0
75Phosphoserine.Swiss-Prot 53.0
78Phosphoserine.Swiss-Prot 53.0
125Phosphoserine.Swiss-Prot 53.0
125PhosphoserinePhospho.ELM 6.0
1718PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
12Phosphoserine(CK1)HMM predict
12Phosphoserine(CK2)HMM predict
16SulfotyrosineHMM predict
16Phosphotyrosine(Syk)HMM predict
16Phosphotyrosine(SRC)HMM predict
16Phosphotyrosine(INSR)HMM predict
27Phosphothreonine(PKC)HMM predict
73Phosphoserine(CK2)HMM predict
73Phosphoserine(CK1)HMM predict
73Phosphoserine(CK2)HMM predict
75PhosphoserineHMM predict
75Phosphoserine(ATM)HMM predict
90Phosphothreonine(PKA)HMM predict
91Phosphoserine(PKC)HMM predict
91Phosphoserine(PKA)HMM predict
125Phosphoserine(CK2)HMM predict
135SulfotyrosineHMM predict
135Phosphotyrosine(Syk)HMM predict
135Phosphotyrosine(SRC)HMM predict
135Phosphotyrosine(EGFR)HMM predict
135Phosphotyrosine(INSR)HMM predict
179Phosphoserine(CK2)HMM predict
179Phosphoserine(CK1)HMM predict
205Phosphotyrosine(INSR)HMM predict
223SulfotyrosineHMM predict
223Phosphotyrosine(EGFR)HMM predict
229Phosphotyrosine(Syk)HMM predict
232SulfotyrosineHMM predict
232Phosphotyrosine(Syk)HMM predict
240SulfotyrosineHMM predict
242SulfotyrosineHMM predict
258Phosphothreonine(PKC)HMM predict
259Phosphothreonine(PKC)HMM predict
335PhosphoserineHMM predict
338Phosphotyrosine(Syk)HMM predict
349O-linkedHMM predict
383Phosphotyrosine(Syk)HMM predict
383Phosphotyrosine(INSR)HMM predict
412N-linkedHMM predict
524Phosphotyrosine(Jak)HMM predict
525Phosphothreonine(Jak)HMM predict
542Phosphothreonine(MAPK)HMM predict
576Phosphoserine(ATM)HMM predict
580Phosphothreonine(MAPK)HMM predict
580Phosphothreonine(CDC2)HMM predict
617N-linkedHMM predict
635SulfotyrosineHMM predict
710Phosphothreonine(PKA)HMM predict
722Phosphotyrosine(Jak)HMM predict
906Phosphotyrosine(EGFR)HMM predict
933Phosphoserine(CK1)HMM predict
998Phosphothreonine(PKA)HMM predict
1007N-linkedHMM predict
1008N-linkedHMM predict
1063Phosphotyrosine(SRC)HMM predict
1076SulfotyrosineHMM predict
1079Phosphoserine(CK2)HMM predict
1170N-linkedHMM predict
1184Phosphotyrosine(EGFR)HMM predict
1220Phosphoserine(IKK)HMM predict
1300Phosphotyrosine(Syk)HMM predict
1301SulfotyrosineHMM predict
1432Phosphotyrosine(Syk)HMM predict
1486Phosphotyrosine(Jak)HMM predict
1515Phosphotyrosine(EGFR)HMM predict
1523Phosphothreonine(MAPK)HMM predict
1528O-linkedHMM predict
1530O-linkedHMM predict
1535Phosphoserine(IKK)HMM predict
1537N-linkedHMM predict
1542N-linkedHMM predict
1558N-linkedHMM predict
1578N-linkedHMM predict
1606O-linkedHMM predict
1614O-linkedHMM predict
1618O-linkedHMM predict
1618PhosphothreonineHMM predict
1618Phosphothreonine(MAPK)HMM predict
1624O-linkedHMM predict
1625O-linkedHMM predict
1627O-linkedHMM predict
1643Phosphothreonine(CDK)HMM predict
1643Phosphothreonine(MAPK)HMM predict
1655Phosphoserine(CDC2)HMM predict
1697Phosphothreonine(MAPK)HMM predict
1701Phosphoserine(CDC2)HMM predict
1703O-linkedHMM predict
1703Phosphoserine(CDC2)HMM predict
1712Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003170
  • Location:chr17 24013428-24053374
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 24012546 24013962 1416 175
GABP k562GSE8489 24011430 24015345 3915 41
H3ac HepG2E 24011430 24015286 3856 71
PHF8 293TGSE20725 24012608 24014196 1588 27
TAFII hESGSE17917 24013187 24013499 312 86
p130 shRbSenescentGSE19898 24013116 24013579 463 81
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 24027062 24027452 390 0
CTCF G2GSE9613 24052250 24052581 331 0
GABP k562GSE8489 24015670 24016568 898 0
H3K4me3 colorectalcancer 24012350 24014692 2342 0
H3ac HepG2E 24048541 24049526 985 0
Oct1 H2O2-HelaGSE14283 24026011 24026052 41 0
Oct1 H2O2-HelaGSE14283 24033934 24033964 30 0
Oct1 H2O2-HelaGSE14283 24043925 24043952 27 0
Oct1 H2O2-HelaGSE14283 24046474 24046512 38 0
Oct1 H2O2-HelaGSE14283 24049083 24049119 36 0
Oct1 HelaGSE14283 24015780 24015812 32 0
Oct1 HelaGSE14283 24026010 24026053 43 0
Oct1 HelaGSE14283 24029675 24029723 48 0
Oct1 HelaGSE14283 24033934 24033967 33 0
Oct1 HelaGSE14283 24046473 24046536 63 0
Oct1 HelaGSE14283 24049083 24049116 33 0
RARG MCF7GSE15244 24035604 24036175 571 0
TAF k562GSE8489 24012692 24014553 1861 0
hScc1 BcellGSE12603 24051929 24052276 347 0
p130 shRbQuiescentGSE19898 24012937 24014050 1113 0
p63 keratinocytesGSE17611 24019118 24019955 837 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
10857 mRNA SUPT6H chr17 24013342 24052877 48 EST chr17 24021198 24023949Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved