AutismKB 2.0

Annotation Detail for SVIL


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SVIL ( DKFZp686A17191 )
Gene Full Name: supervillin
Band: 10p11.23
Quick LinksEntrez ID:6840; OMIM: 604126; Uniprot ID:SVIL_HUMAN; ENSEMBL ID: ENSG00000197321; HGNC ID: 11480
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
50Phosphoserine.
221Phosphoserine.
245Phosphoserine.
263Phosphoserine.
270Phosphoserine.
673Phosphoserine (By similarity).
675Phosphoserine (By similarity).
707Phosphoserine.
736Phosphothreonine.
852Phosphothreonine.
920Phosphoserine.
1000Phosphoserine (By similarity).
1052Phosphoserine (By similarity).
1111Phosphothreonine.
1120Phosphoserine.
1175Phosphothreonine.
1225Phosphoserine.
1322Phosphoserine.
Location(AA) Modifications Resource
221Phosphoserine.Swiss-Prot 53.0
221PhosphoserinePhospho.ELM 6.0
226PhosphoserinePhospho.ELM 6.0
245Phosphoserine.Swiss-Prot 53.0
245PhosphoserinePhospho.ELM 6.0
261PhosphoserinePhospho.ELM 6.0
270PhosphoserinePhospho.ELM 6.0
673Phosphoserine (By similarity).Swiss-Prot 53.0
675Phosphoserine (By similarity).Swiss-Prot 53.0
852PhosphothreoninePhospho.ELM 6.0
852Phosphothreonine.Swiss-Prot 53.0
1000PhosphoserinePhospho.ELM 6.0
1052Phosphoserine (By similarity).Swiss-Prot 53.0
1175Phosphothreonine.Swiss-Prot 53.0
1175PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
16N-linkedHMM predict
46O-linkedHMM predict
63Phosphoserine(CK1)HMM predict
66Phosphoserine(CK1)HMM predict
90O-linkedHMM predict
97Phosphoserine(IKK)HMM predict
132Phosphotyrosine(Syk)HMM predict
160Phosphoserine(CK1)HMM predict
185Phosphotyrosine(INSR)HMM predict
229O-linkedHMM predict
238Phosphoserine(IKK)HMM predict
238Phosphoserine(PKB)HMM predict
245Phosphoserine(CDC2)HMM predict
245PhosphoserineHMM predict
251Phosphoserine(CK1)HMM predict
253Phosphoserine(CK1)HMM predict
263Phosphoserine(PKC)HMM predict
263Phosphoserine(IKK)HMM predict
277Phosphothreonine(PKC)HMM predict
328Phosphothreonine(PKC)HMM predict
359Phosphoserine(PKC)HMM predict
381Phosphothreonine(MAPK)HMM predict
384Phosphothreonine(CDC2)HMM predict
384Phosphothreonine(MAPK)HMM predict
387N-linkedHMM predict
392O-linkedHMM predict
396O-linkedHMM predict
525Phosphoserine(ATM)HMM predict
582Phosphotyrosine(SRC)HMM predict
644Phosphoserine(CAMK2)HMM predict
644Phosphoserine(CDC2)HMM predict
644Phosphoserine(ATM)HMM predict
673O-linkedHMM predict
673Phosphoserine(CK1)HMM predict
693Phosphoserine(PKG)HMM predict
734Phosphoserine(IKK)HMM predict
757O-linkedHMM predict
769Phosphoserine(CDC2)HMM predict
810Phosphoserine(IKK)HMM predict
826Phosphoserine(ATM)HMM predict
830O-linkedHMM predict
830Phosphoserine(IKK)HMM predict
841Phosphothreonine(PKC)HMM predict
872Phosphoserine(CDC2)HMM predict
876N-linkedHMM predict
878O-linkedHMM predict
880O-linkedHMM predict
880O-linkedHMM predict
880O-linkedHMM predict
881O-linkedHMM predict
884O-linkedHMM predict
903N-linkedHMM predict
920Phosphoserine(CDC2)HMM predict
920Phosphoserine(CDK)HMM predict
920PhosphoserineHMM predict
947SulfotyrosineHMM predict
957Phosphothreonine(PKC)HMM predict
968Phosphoserine(CK2)HMM predict
993Phosphotyrosine(INSR)HMM predict
1000Phosphoserine(PKC)HMM predict
1000Phosphoserine(PKG)HMM predict
1052Phosphoserine(PKG)HMM predict
1068O-linkedHMM predict
1073O-linkedHMM predict
1120Phosphoserine(CDC2)HMM predict
1159Phosphoserine(CK1)HMM predict
1175Phosphothreonine(PKA)HMM predict
1175Phosphothreonine(PKC)HMM predict
1200Phosphothreonine(PKC)HMM predict
1207N-linkedHMM predict
1225Phosphoserine(CDC2)HMM predict
1230O-linkedHMM predict
1230Phosphothreonine(MAPK)HMM predict
1240O-linkedHMM predict
1243Phosphothreonine(PKA)HMM predict
1244Phosphothreonine(CDK)HMM predict
1322Phosphoserine(CDC2)HMM predict
1403N-linkedHMM predict
1417N-linkedHMM predict
1420N-linkedHMM predict
1427N-linkedHMM predict
1432N-linkedHMM predict
1434N-linkedHMM predict
1435N-linkedHMM predict
1479S-palmitoylHMM predict
1480S-palmitoylHMM predict
1505Phosphothreonine(PKC)HMM predict
1566SulfotyrosineHMM predict
1628N-linkedHMM predict
1717Phosphoserine(CAMK2)HMM predict
1822Phosphothreonine(PKC)HMM predict
1901S-palmitoylHMM predict
1911Phosphoserine(MAPK)HMM predict
1959Phosphoserine(CK1)HMM predict
1987Phosphotyrosine(INSR)HMM predict
2016O-linkedHMM predict
2026O-linkedHMM predict
2026Phosphoserine(IKK)HMM predict
2026Phosphoserine(PKB)HMM predict
2039Phosphotyrosine(Abl)HMM predict
2039Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003174
  • Location:chr10 29786282-30064735
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 30064749 30065011 262 145
CTCF CD4SISSRdata 30064749 30065011 262 145
CTCF JurkatGSE12889 30064776 30065030 254 168
RARA MCF7GSE15244 30075105 30075488 383 10561
RARG MCF7GSE15244 30075127 30075447 320 10552
hScc1 BcellGSE12603 30065765 30066205 440 1250
p130 SenescentGSE19898 30075378 30075715 337 10811
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 29987506 29989067 1561 0
Fos K562GSE19551 29987955 29988259 304 0
H3K4me2 HCT116GSE10453 30063185 30063935 750 0
H3K4me3 colorectalcancer 30063291 30063822 531 0
H3ac HepG2E 29964103 29964800 697 0
H3ac HepG2E 30062897 30063981 1084 0
NFkBII GM12878GSE19485 29987367 29989102 1735 0
NFkBII GM15510GSE19485 29987498 29988901 1403 0
NRSF-poly JurkatQuESTdata 30016806 30017021 215 0
Nanog hESGSE18292 29973127 29973356 229 0
Nanog hESGSE18292 29995875 29996580 705 0
Oct1 HelaGSE14283 29974729 29974765 36 0
P300 T30-glioblastomaGSE21026 29987480 29989148 1668 0
P300 T30-glioblastomaGSE21026 30017930 30018554 624 0
RARA MCF7GSE15244 29987723 29988526 803 0
RARA MCF7GSE15244 29990119 29990732 613 0
RARA MCF7GSE15244 29994906 29995746 840 0
RARG MCF7GSE15244 29987794 29988614 820 0
RARG MCF7GSE15244 29990119 29990699 580 0
RARG MCF7GSE15244 29994872 29995746 874 0
RARG MCF7GSE15244 29997724 29997967 243 0
RARG MCF7GSE15244 30026781 30027216 435 0
Rb GrowingGSE19898 29987155 29987329 174 0
Rb GrowingGSE19898 30016705 30016925 220 0
Rb shRbQuiescentGSE19898 30057813 30058084 271 0
TFAP2C MCF7GSE21234 30017074 30017403 329 0
TFAP2C MCF7GSE21234 30028387 30028926 539 0
USF1 HepG2E 29986188 29986981 793 0
USF2 HepG2E 29986330 29987382 1052 0
hScc1 BcellGSE12603 30026781 30026931 150 0
hScc1 BcellGSE12603 30064272 30065100 828 0
hScc1 CdLSGSE12603 30064086 30065064 978 0
hScc1 G2GSE9613 30063862 30065243 1381 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2960 mRNA chr10 29738525 29814641 176 mRNA SVIL chr10 29786282 30064736Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved