Annotation Detail for SYPL1

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Basic Information Top

Gene Symbol:	SYPL1 ( H-SP1,SYPL )
Gene Full Name:	synaptophysin-like 1
Band:	7q22.2
Quick Links	Entrez ID:6856; OMIM: NA; Uniprot ID:SYPL1_HUMAN; ENSEMBL ID: ENSG00000008282; HGNC ID: 11507
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
71	N-linked (GlcNAc...).
212	N-linked (GlcNAc...) (Potential).

Location(AA)	Modifications	Resource
71	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
212	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Oct1	Hela	GSE14283	105543094	105543142	48	2826
hScc1	Bcell	GSE12603	105540188	105540534	346	69

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
929	Unknown	pSILAC	LNA_let-7b	SYPL1	up >75%	18668040
1009	Unknown	pSILAC	miR-155	SYPL1	down 75-50%	18668040
1286	Unknown	pSILAC	miR-30	SYPL1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000008282		n_a	n_a	n_a	"epithelium, lymphoblast, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000008282		n_a	n_a	n_a	"epithelium, lymphoblast, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000008282		n_a	n_a	n_a	"epithelium, lymphoblast, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018