AutismKB 2.0

Annotation Detail for SYT1


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Basic Information Top
Gene Symbol:SYT1 ( DKFZp781D2042,P65,SVP65,SYT )
Gene Full Name: synaptotagmin I
Band: 12q21.2
Quick LinksEntrez ID:6857; OMIM: 185605; Uniprot ID:SYT1_HUMAN; ENSEMBL ID: ENSG00000067715; HGNC ID: 11509
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
25N-linked (GlcNAc...) (Potential).
129Phosphothreonine (By similarity).
230Phosphotyrosine (By similarity).
237N6-acetyllysine.
365Phosphotyrosine (By similarity).
381Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
25N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
75S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
76S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
78S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
80S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
83S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
129Phosphothreonine (By similarity).Swiss-Prot 53.0
365Phosphotyrosine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
16O-linkedHMM predict
17O-linkedHMM predict
20O-linkedHMM predict
25N-linkedHMM predict
31Phosphoserine(MAPK)HMM predict
41Phosphoserine(CK1)HMM predict
76S-palmitoylHMM predict
382N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005639
  • Location:chr12 78135413-78368970
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 78125058 78125242 184 10264
Oct1 H2O2-HelaGSE14283 78128761 78128796 35 6635
Oct1 H2O2-HelaGSE14283 78135293 78135319 26 108
Oct1 HelaGSE14283 78128750 78128802 52 6638
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 78369986 78370458 472 1252
Oct1 H2O2-HelaGSE14283 78370918 78370945 27 1961
RARA MCF7GSE15244 78369832 78370458 626 1175
RARA MCF7GSE15244 78371998 78372618 620 3338
RARG MCF7GSE15244 78369646 78370458 812 1082
RARG MCF7GSE15244 78372067 78372521 454 3324
Rb shRbSenescenceGSE19898 78368892 78369139 247 45
TFAP2C MCF7GSE21234 78369804 78370295 491 1079
TFAP2C MCF7GSE21234 78370791 78371251 460 2051
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 78327255 78328189 934 0
CTCF JurkatGSE12889 78325954 78326200 246 0
CTCF G2GSE9613 78292501 78292767 266 0
CTCF G2GSE9613 78325701 78326206 505 0
CTCF G2GSE9613 78338256 78338482 226 0
ER E2-MCF7GSE14664 78208522 78208559 37 0
ER Fulvestrant-MCF7GSE14664 78146546 78146578 32 0
ER Fulvestrant-MCF7GSE14664 78208512 78208559 47 0
FOXA1 DLD1GSE12801 78212509 78213058 549 0
FOXA1 DLD1GSE12801 78281860 78282495 635 0
FOXA1 DLD1GSE12801 78333698 78334260 562 0
FOXA1 DLD1GSE12801 78341934 78342801 867 0
FOXA1 MCF7GSE15244 78217906 78218415 509 0
FOXA1 MCF7GSE15244 78333698 78334181 483 0
FOXA1 MCF7GSE15244 78342004 78342569 565 0
FoxA1 MCF7MACSdata 78342213 78342432 219 0
GATA3 MCF7GSE15244 78332157 78332696 539 0
GATA3 MCF7GSE15244 78341410 78342275 865 0
Nanog ESGSE20650 78165377 78165910 533 0
Nanog hESGSE18292 78165283 78165743 460 0
Oct1 H2O2-HelaGSE14283 78137157 78137187 30 0
Oct1 H2O2-HelaGSE14283 78159841 78159872 31 0
Oct1 H2O2-HelaGSE14283 78165651 78165682 31 0
Oct1 H2O2-HelaGSE14283 78180412 78180461 49 0
Oct1 H2O2-HelaGSE14283 78222977 78223015 38 0
Oct1 H2O2-HelaGSE14283 78239145 78239172 27 0
Oct1 H2O2-HelaGSE14283 78268349 78268382 33 0
Oct1 H2O2-HelaGSE14283 78338539 78338567 28 0
Oct1 HelaGSE14283 78137146 78137213 67 0
Oct1 HelaGSE14283 78165959 78166000 41 0
Oct1 HelaGSE14283 78180411 78180472 61 0
Oct1 HelaGSE14283 78208508 78208561 53 0
Oct1 HelaGSE14283 78208591 78208626 35 0
P300 T30-glioblastomaGSE21026 78327357 78328204 847 0
RARA MCF7GSE15244 78217873 78218489 616 0
RARA MCF7GSE15244 78225850 78226128 278 0
RARA MCF7GSE15244 78325447 78326358 911 0
RARA MCF7GSE15244 78332085 78332507 422 0
RARG MCF7GSE15244 78332085 78332473 388 0
STAT1 HeLaGSE12783 78341949 78342826 877 0
TAF HelaGSE8489 78154067 78154843 776 0
TFAP2C MCF7GSE21234 78285029 78285629 600 0
hScc1 CdLSGSE12603 78262766 78263180 414 0
hScc1 CdLSGSE12603 78325774 78326244 470 0
hScc1 G2GSE9613 78292572 78292767 195 0
hScc1 G2GSE9613 78325701 78326322 621 0
hScc1 G2GSE9613 78338256 78338521 265 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
6343 mRNA SYT1 chr12 78113750 78347311 524 EST chr12 78346390 78346914Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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