Annotation Detail for TAC1
Basic Information Top
| Gene Symbol: | TAC1 ( Hs.2563,NK2,NKNA,NPK,TAC2 ) |
|---|---|
| Gene Full Name: | tachykinin, precursor 1 |
| Band: | 7q21.3 |
| Quick Links | Entrez ID:6863; OMIM: 162320; Uniprot ID:TKN1_HUMAN; ENSEMBL ID: ENSG00000006128; HGNC ID: 11517 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 68 | Methionine amide. | |
| 107 | Methionine amide. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 68 | Methionine amide (G-69 provides amidegroup). | Swiss-Prot 53.0 |
| 107 | Methionine amide (G-108 provides amidegroup). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 100 | Phosphothreonine(PKA) | HMM predict |
- RefSeq ID: NM_003182
- Location:chr7 97199310-97207717
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ER | E2-MCF7 | GSE14664 | 97183695 | 97183728 | 33 | 15599 |
| H3K27me3 | colorectal | cancer | 97198448 | 97199399 | 951 | 387 |
| Oct1 | Hela | GSE14283 | 97183696 | 97183726 | 30 | 15600 |
| Oct1 | Hela | GSE14283 | 97190546 | 97190576 | 30 | 8750 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Oct1 | H2O2-Hela | GSE14283 | 97210190 | 97210229 | 39 | 2492 |
| Oct1 | H2O2-Hela | GSE14283 | 97222287 | 97222315 | 28 | 14584 |
| Oct1 | Hela | GSE14283 | 97210175 | 97210233 | 58 | 2487 |
| No data |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-130a | hsa-mir-130a | 11 | 17855557 |
| hsa-miR-130a* | hsa-mir-130a | 11 | 17855557 |
| hsa-miR-181b | hsa-mir-181b-1 | 1 | 20347265 |
| hsa-miR-181b | hsa-mir-181b-2 | 9 | 20347265 |
| hsa-miR-198 | hsa-mir-198 | 0 | 20347265 |
| hsa-miR-206 | hsa-mir-206 | 6 | 20347265 |
| hsa-miR-206 | hsa-mir-206 | 6 | 17855557 |
| hsa-miR-24 | hsa-mir-24-1 | 9 | 20347265 |
| hsa-miR-24 | hsa-mir-24-2 | 19 | 20347265 |
| hsa-miR-24-1* | hsa-mir-24-1 | 9 | 20347265 |
| hsa-miR-24-2* | hsa-mir-24-2 | 19 | 20347265 |
| hsa-miR-26b | hsa-mir-26b | 2 | 20347265 |
| hsa-miR-26b* | hsa-mir-26b | 2 | 20347265 |
| hsa-miR-302a | hsa-mir-302a | 4 | 17855557 |
| hsa-miR-302a* | hsa-mir-302a | 4 | 17855557 |
| hsa-miR-30b | hsa-mir-30b | 8 | 20347265 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 20347265 |
| hsa-miR-30e | hsa-mir-30e | 1 | 20347265 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 20347265 |
| hsa-miR-320a | hsa-mir-320a | 8 | 17855557 |
| hsa-miR-92a | hsa-mir-92a-1 | 13 | 20347265 |
| hsa-miR-92a | hsa-mir-92a-2 | X | 20347265 |
| hsa-miR-92a-1* | hsa-mir-92a-1 | 13 | 20347265 |
| hsa-miR-92a-2* | hsa-mir-92a-2 | X | 20347265 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 444 | mRNA repression | TRUE | miR-130a | TAC1 | Luciferase assay | 17855557 |
| 526 | mRNA repression | TRUE | miR-206 | TAC1 | Luciferase assay | 17855557 |
| 601 | Unknown | FALSE | miR-302a | TAC1 | Luciferase assay | 17855557 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000006128 | "mesenchymal stem cells, vascular endothelial cell" | Substance P production | n_a | n_a | n_a | |
| ENSG00000006128 | mesenchymal-epithelial transition (MET) | n_a | n_a | n_a | n_a | |
| ENSG00000006128 | n_a | n_a | n_a | n_a | n_a |
Cis-Nats regulation