Annotation Detail for TCEB2

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Basic Information Top

Gene Symbol:	TCEB2 ( ELOB,SIII )
Gene Full Name:	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
Band:	16p12.3
Quick Links	Entrez ID:6923; OMIM: 600787; Uniprot ID:ELOB_HUMAN; ENSEMBL ID: ENSG00000103363; HGNC ID:
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:5 results

Location(AA)	Modification
1	N-acetylmethionine.

Location(AA)	Modification	Resource
12	Phosphothreonine(PKA)	HMM predict
21	Phosphoserine(PKG)	HMM predict
95	Phosphoserine(CDC2)	HMM predict
100	Proline	HMM predict
110	Phosphoserine(CK2)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_207013
Location:chr16 2761416-2767297
strand:-

Upstream the gene:10 results
Downstream the gene:0 results
Inside the gene:10 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	2767998	2768299	301	851
ETS1	Jurkat	GSE17954	2766778	2768088	1310	136
H3ac	HepG2	E	2767560	2768505	945	735
NFkBII	GM10847	GSE19485	2766777	2768101	1324	142
P300	T30-glioblastoma	GSE21026	2766509	2768553	2044	234
PHF8	HeLa	GSE20725	2766585	2768439	1854	215
PHF8	Hs68plusFBS	GSE20725	2766288	2768892	2604	293
TAF	Hela	GSE8489	2768895	2769060	165	1680
p130	shRbQuiescent	GSE19898	2767423	2767984	561	406
p130	shRbQuiescent	GSE19898	2768073	2768627	554	1053

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	2761728	2762040	312	0
CTCF	G2	GSE9613	2766979	2767410	431	0
ER	Breast-Cancer	GSE22609	2762720	2763199	479	0
H3K4me2	HCT116	GSE10453	2766223	2766545	322	0
H3K4me3	colorectal	cancer	2766223	2766545	322	0
H3ac	HepG2	E	2766223	2766746	523	0
NFkBII	GM18526	GSE19485	2766316	2768216	1900	0
TAF	Hela	GSE8489	2765468	2765655	187	0
hScc1	Bcell	GSE12603	2762930	2763148	218	0
hScc1	CdLS	GSE12603	2766825	2767374	549	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
9497	EST		chr16	2760441	2761783	25	EST	TCEB2	chr16	2761009	2767299	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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