AutismKB 2.0

Annotation Detail for TCF3


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Basic Information Top
Gene Symbol:TCF3 ( E2A,ITF1,MGC129647,MGC129648,VDIR,bHLHb21 )
Gene Full Name: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
Band: 19p13.3
Quick LinksEntrez ID:6929; OMIM: 147141; Uniprot ID:TFE2_HUMAN; ENSEMBL ID: ENSG00000071564; HGNC ID: 11633
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
279aaTAD.
139Phosphoserine.
176Nuclear localization signal (Potential).
359Phosphoserine.
379Phosphoserine.
Location(AA) Modifications Resource
355Phosphothreonine (MAPK
Location(AA) Modification Resource
55Phosphoserine(CK1)HMM predict
58Phosphoserine(IKK)HMM predict
76Phosphoserine(CAMK2)HMM predict
76Phosphoserine(CK1)HMM predict
86Phosphoserine(IKK)HMM predict
89Phosphoserine(CK1)HMM predict
102O-linkedHMM predict
105MethylarginineHMM predict
134Phosphoserine(MAPK)HMM predict
139Phosphoserine(IKK)HMM predict
139Phosphoserine(CDC2)HMM predict
156Phosphoserine(CDC2)HMM predict
157Phosphoserine(PKC)HMM predict
165Phosphoserine(IKK)HMM predict
183Phosphoserine(ATM)HMM predict
193SulfotyrosineHMM predict
202O-linkedHMM predict
205Phosphothreonine(CDK)HMM predict
205Phosphothreonine(MAPK)HMM predict
205Phosphothreonine(CDC2)HMM predict
208O-linkedHMM predict
209O-linkedHMM predict
229Phosphoserine(IKK)HMM predict
229Phosphoserine(MAPK)HMM predict
244O-linkedHMM predict
245Phosphoserine(CDC2)HMM predict
253O-linkedHMM predict
253O-linkedHMM predict
259Phosphoserine(IKK)HMM predict
261O-linkedHMM predict
291O-linkedHMM predict
294O-linkedHMM predict
295O-linkedHMM predict
300O-linkedHMM predict
305O-linkedHMM predict
308PhosphothreonineHMM predict
308Phosphothreonine(MAPK)HMM predict
316Phosphoserine(IKK)HMM predict
348N-linkedHMM predict
350O-linkedHMM predict
352Phosphoserine(CDC2)HMM predict
352O-linkedHMM predict
352Phosphoserine(CDK)HMM predict
354Phosphoserine(CK1)HMM predict
354O-linkedHMM predict
355O-linkedHMM predict
355Phosphothreonine(CDK)HMM predict
355Phosphothreonine(CDC2)HMM predict
359Phosphoserine(CDC2)HMM predict
467Phosphoserine(IKK)HMM predict
467Phosphoserine(ATM)HMM predict
507N-linkedHMM predict
509Phosphoserine(CK2)HMM predict
514Phosphoserine(CK2)HMM predict
529Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003200
  • Location:chr19 1560294-1601276
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 1603405 1604319 914 2586
Fos K562GSE19551 1603701 1604388 687 2768
NFkBII GM10847GSE19485 1614493 1615525 1032 13733
NFkBII GM12878GSE19485 1611571 1612941 1370 10980
NFkBII GM12878GSE19485 1614373 1615470 1097 13645
NFkBII GM12892GSE19485 1614413 1615472 1059 13666
NFkBII GM15510GSE19485 1614465 1615465 1000 13689
NFkBII GM18505GSE19485 1614478 1615570 1092 13748
NFkBII GM18526GSE19485 1603318 1604769 1451 2767
P300 T30-glioblastomaGSE21026 1603389 1604504 1115 2670
TFAP2C MCF7GSE21234 1608860 1609833 973 8070
TFAP2C MCF7GSE21234 1612004 1612455 451 10953
TFAP2C MCF7GSE21234 1616716 1617227 511 15695
hScc1 BcellGSE12603 1606299 1606529 230 5138
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 1559348 1559727 379 757
VDR GM10861-stimGSE22484 1558201 1561935 3734 227
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 1569265 1569514 249 0
CTCF CD4GSE12889 1575531 1575687 156 0
CTCF CD4SISSRdata 1569265 1569514 249 0
CTCF CD4SISSRdata 1575531 1575687 156 0
CTCF HelaGSE12889 1575493 1575770 277 0
CTCF G2GSE9613 1569179 1569843 664 0
CTCF G2GSE9613 1575397 1575564 167 0
CTCF G2GSE9613 1581205 1581592 387 0
H3ac HepG2E 1578757 1580086 1329 0
KLF4 hESGSE17917 1573528 1573774 246 0
TAF HelaGSE8489 1590395 1590880 485 0
USF1 HepG2E 1563791 1564348 557 0
VDR GM10861-stimGSE22484 1596703 1603331 6628 0
hScc1 BcellGSE12603 1568940 1569950 1010 0
hScc1 BcellGSE12603 1574697 1574896 199 0
hScc1 BcellGSE12603 1575397 1575564 167 0
hScc1 BcellGSE12603 1576251 1576629 378 0
hScc1 BcellGSE12603 1577467 1578683 1216 0
hScc1 BcellGSE12603 1580230 1580487 257 0
hScc1 BcellGSE12603 1583580 1584112 532 0
hScc1 BcellGSE12603 1584828 1585007 179 0
hScc1 BcellGSE12603 1596879 1597693 814 0
hScc1 BcellGSE12603 1599705 1600390 685 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-200b hsa-mir-200b 1 20498046
hsa-miR-200b* hsa-mir-200b 1 20498046
hsa-miR-214 hsa-mir-214 1 20498046
hsa-miR-214* hsa-mir-214 1 20498046
hsa-miR-223 hsa-mir-223 X 20802470
hsa-miR-223* hsa-mir-223 X 20802470
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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