Annotation Detail for ZEB1

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	ZEB1 ( AREB6,BZP,DELTAEF1,FECD6,MGC133261,NIL2A,TCF8,ZFHEP,ZFHX1A )
Gene Full Name:	zinc finger E-box binding homeobox 1
Band:	10p11.22
Quick Links	Entrez ID:6935; OMIM: 189909; Uniprot ID:ZEB1_HUMAN; ENSEMBL ID: ENSG00000148516; HGNC ID: 11642
Relate to Another Database:	SFARIGene; denovo-db

General

Expression

Regulation

Pathways, Diseases and Drugs

PTM

TF binding site

miRNA targets

Cis-NATs

Post Translation Modification

Top

PTM Sites from Uniprot:9 results
Experimental PTM Sites from dbPTM:10 results
Predicted PTM Sites by profile HMM from dbPTM:97 results

Location(AA)	Modification
31	Phosphoserine.
33	Phosphoserine.
322	Phosphoserine.
583	Phosphoserine.
642	Phosphoserine.
646	Phosphoserine.
679	Phosphoserine.
702	Phosphothreonine.
704	Phosphoserine.

Location(AA)	Modifications	Resource
31	Phosphoserine.	Swiss-Prot 53.0
31	Phosphoserine	Phospho.ELM 6.0
33	Phosphoserine.	Swiss-Prot 53.0
33	Phosphoserine	Phospho.ELM 6.0
347	Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).	Swiss-Prot 53.0
679	Phosphoserine	Phospho.ELM 6.0
679	Phosphoserine.	Swiss-Prot 53.0
698	Phosphoserine	Phospho.ELM 6.0
704	Phosphoserine	Phospho.ELM 6.0
774	Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).	Swiss-Prot 53.0

Location(AA)	Modification	Resource
19	N-linked	HMM predict
22	N-linked	HMM predict
23	Phosphotyrosine(Abl)	HMM predict
24	N-linked	HMM predict
33	Phosphoserine(CK2)	HMM predict
33	Phosphoserine(ATM)	HMM predict
46	Phosphoserine(CK1)	HMM predict
114	Phosphoserine(CK2)	HMM predict
114	Phosphoserine(CK1)	HMM predict
160	N-linked	HMM predict
175	S-palmitoyl	HMM predict
184	Phosphoserine(PKA)	HMM predict
199	N-linked	HMM predict
220	Phosphothreonine(PKC)	HMM predict
245	S-palmitoyl	HMM predict
268	Phosphotyrosine(INSR)	HMM predict
268	Phosphotyrosine(SRC)	HMM predict
309	Phosphoserine(IKK)	HMM predict
312	O-linked	HMM predict
313	Phosphoserine(CDK)	HMM predict
313	Phosphoserine(IKK)	HMM predict
313	Phosphoserine(CDC2)	HMM predict
315	O-linked	HMM predict
317	O-linked	HMM predict
319	Phosphoserine(CDC2)	HMM predict
319	Phosphoserine(CDK)	HMM predict
319	Phosphoserine(ATM)	HMM predict
319	Phosphoserine(IKK)	HMM predict
322	Phosphoserine(IKK)	HMM predict
322	Phosphoserine(CDC2)	HMM predict
342	Phosphoserine(CK1)	HMM predict
365	N-linked	HMM predict
386	Phosphoserine(ATM)	HMM predict
386	Phosphoserine(CDC2)	HMM predict
408	N-linked	HMM predict
414	N-linked	HMM predict
445	N-linked	HMM predict
527	N-linked	HMM predict
571	Phosphoserine(IKK)	HMM predict
572	Phosphoserine(CK1)	HMM predict
572	O-linked	HMM predict
574	O-linked	HMM predict
581	N-linked	HMM predict
583	Phosphoserine(CDC2)	HMM predict
583	O-linked	HMM predict
583	Phosphoserine(CDK)	HMM predict
585	Phosphoserine(ATM)	HMM predict
612	Phosphoserine(CK1)	HMM predict
642	Phosphoserine(IKK)	HMM predict
645	O-linked	HMM predict
645	Phosphoserine(CK1)	HMM predict
646	Phosphoserine(ATM)	HMM predict
646	Phosphoserine(CDC2)	HMM predict
646	Phosphoserine(MAPK)	HMM predict
646	Phosphoserine(CDK)	HMM predict
679	Phosphoserine(CDC2)	HMM predict
696	N-linked	HMM predict
698	O-linked	HMM predict
700	O-linked	HMM predict
701	Phosphoserine(IKK)	HMM predict
701	O-linked	HMM predict
702	O-linked	HMM predict
702	Phosphothreonine(MAPK)	HMM predict
702	Phosphothreonine(CDK)	HMM predict
704	Phosphoserine(CDC2)	HMM predict
704	O-linked	HMM predict
706	Phosphoserine(CDC2)	HMM predict
709	N-linked	HMM predict
711	Phosphoserine(CDC2)	HMM predict
715	N-linked	HMM predict
781	Phosphoserine(IKK)	HMM predict
843	Phosphotyrosine(Jak)	HMM predict
844	O-linked	HMM predict
847	O-linked	HMM predict
848	O-linked	HMM predict
848	O-linked	HMM predict
850	Phosphoserine(CDK)	HMM predict
850	Phosphoserine(MAPK)	HMM predict
850	Phosphoserine(CDC2)	HMM predict
875	Phosphoserine(CK1)	HMM predict
885	N-linked	HMM predict
890	Phosphothreonine(CDC2)	HMM predict
890	Phosphothreonine(CDK)	HMM predict
890	Phosphothreonine(MAPK)	HMM predict
918	Phosphoserine(CK1)	HMM predict
976	Phosphoserine(ATM)	HMM predict
995	Phosphoserine	HMM predict
995	Phosphoserine(CK1)	HMM predict
1018	Phosphoserine(IKK)	HMM predict
1018	Phosphoserine(ATM)	HMM predict
1027	Phosphoserine(CK1)	HMM predict
1036	Phosphoserine(CK1)	HMM predict
1036	Phosphoserine(CK2)	HMM predict
1100	Phosphoserine(CK2)	HMM predict
1100	Phosphoserine(IKK)	HMM predict
1100	Phosphoserine(PKG)	HMM predict
1100	Phosphoserine(ATM)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_030751
Location:chr10 31648147-31856739
strand:+

Upstream the gene:6 results
Downstream the gene:1 results
Inside the gene:11 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ETS1	Jurkat	GSE17954	31646966	31648683	1717	323
H3ac	HepG2	E	31646730	31647635	905	965
PHF8	HeLa	GSE20725	31647143	31648898	1755	127
Pol2	GM12878	GSE19551	31647013	31648735	1722	274
hScc1	Bcell	GSE12603	31647164	31648047	883	542
hScc1	CdLS	GSE12603	31647057	31648047	990	596

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Stat6	IL-4-hr4	GSE17850	31872809	31873381	572	16356

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	31820147	31820362	215
CTCF	CD4	SISSRdata	31820147	31820362	215
FoxA1	MCF7	MACSdata	31730255	31730626	371
H3K27me3	colorectal	cancer	31650054	31650572	518
Myc	K562	GSE19551	31733585	31733923	338
Oct1	Hela	GSE14283	31813522	31813551	29
Oct4	hES	GSE17917	31797210	31797548	338
hScc1	Bcell	GSE12603	31648354	31649671	1317
hScc1	Bcell	GSE12603	31797100	31797323	223
hScc1	CdLS	GSE12603	31648354	31650349	1995
hScc1	CdLS	GSE12603	31651543	31651979	436

Validated miRNA targets

Top

miR Walk:252 results
Tarbase V5.0:5 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7a	hsa-let-7a-1	9	21285251
hsa-let-7a	hsa-let-7a-2	11	21285251
hsa-let-7a	hsa-let-7a-3	22	21285251
hsa-let-7a	hsa-let-7a-1	9	19654291
hsa-let-7a	hsa-let-7a-2	11	19654291
hsa-let-7a	hsa-let-7a-3	22	19654291
hsa-let-7a*	hsa-let-7a-1	9	19654291
hsa-let-7a*	hsa-let-7a-3	22	19654291
hsa-let-7b	hsa-let-7b	22	19654291
hsa-let-7b*	hsa-let-7b	22	19654291
hsa-let-7c	hsa-let-7c	21	19654291
hsa-let-7c*	hsa-let-7c	21	19654291
hsa-let-7d	hsa-let-7d	9	19654291
hsa-let-7d*	hsa-let-7d	9	19654291
hsa-let-7e	hsa-let-7e	19	19654291
hsa-let-7e*	hsa-let-7e	19	19654291
hsa-let-7f	hsa-let-7f-1	9	20716115
hsa-let-7f	hsa-let-7f-2	X	20716115
hsa-let-7f	hsa-let-7f-1	9	19654291
hsa-let-7f	hsa-let-7f-2	X	19654291
hsa-let-7f-1*	hsa-let-7f-1	9	19654291
hsa-let-7f-2*	hsa-let-7f-2	X	19654291
hsa-let-7g	hsa-let-7g	3	19654291
hsa-let-7g*	hsa-let-7g	3	19654291
hsa-let-7i	hsa-let-7i	12	19654291
hsa-let-7i*	hsa-let-7i	12	19654291
hsa-miR-10a	hsa-mir-10a	17	20588024
hsa-miR-10a*	hsa-mir-10a	17	20588024
hsa-miR-141	hsa-mir-141	12	21224847
hsa-miR-141	hsa-mir-141	12	20682048
hsa-miR-141	hsa-mir-141	12	19910931
hsa-miR-141	hsa-mir-141	12	19901913
hsa-miR-141	hsa-mir-141	12	19502803
hsa-miR-141	hsa-mir-141	12	18698484
hsa-miR-141	hsa-mir-141	12	18483486
hsa-miR-141	hsa-mir-141	12	18376396
hsa-miR-141	hsa-mir-141	12	18381893
hsa-miR-141	hsa-mir-141	12	18411277
hsa-miR-141	hsa-mir-141	12	19854497
hsa-miR-141*	hsa-mir-141	12	21224847
hsa-miR-141*	hsa-mir-141	12	20682048
hsa-miR-141*	hsa-mir-141	12	19910931
hsa-miR-141*	hsa-mir-141	12	19901913
hsa-miR-141*	hsa-mir-141	12	19502803
hsa-miR-141*	hsa-mir-141	12	18698484
hsa-miR-141*	hsa-mir-141	12	18483486
hsa-miR-141*	hsa-mir-141	12	18376396
hsa-miR-141*	hsa-mir-141	12	18381893
hsa-miR-141*	hsa-mir-141	12	18411277
hsa-miR-141*	hsa-mir-141	12	19854497
hsa-miR-144	hsa-mir-144	17	21285251
hsa-miR-144*	hsa-mir-144	17	21285251
hsa-miR-145	hsa-mir-145	5	20716115
hsa-miR-145*	hsa-mir-145	5	20716115
hsa-miR-155	hsa-mir-155	21	21125666
hsa-miR-155	hsa-mir-155	21	21038317
hsa-miR-155*	hsa-mir-155	21	21125666
hsa-miR-155*	hsa-mir-155	21	21038317
hsa-miR-17	hsa-mir-17	13	20037478
hsa-miR-17*	hsa-mir-17	13	20037478
hsa-miR-182	hsa-mir-182	7	20716115
hsa-miR-182	hsa-mir-182	7	19167416
hsa-miR-182*	hsa-mir-182	7	20716115
hsa-miR-182*	hsa-mir-182	7	19167416
hsa-miR-183	hsa-mir-183	7	19935649
hsa-miR-183*	hsa-mir-183	7	19935649
hsa-miR-191	hsa-mir-191	3	20037478
hsa-miR-191*	hsa-mir-191	3	20037478
hsa-miR-192	hsa-mir-192	11	20056746
hsa-miR-192	hsa-mir-192	11	19910931
hsa-miR-192	hsa-mir-192	11	19901913
hsa-miR-192	hsa-mir-192	11	21389977
hsa-miR-192*	hsa-mir-192	11	20056746
hsa-miR-192*	hsa-mir-192	11	19910931
hsa-miR-192*	hsa-mir-192	11	19901913
hsa-miR-192*	hsa-mir-192	11	21389977
hsa-miR-200a	hsa-mir-200a	1	21285251
hsa-miR-200a	hsa-mir-200a	1	20668090
hsa-miR-200a	hsa-mir-200a	1	20484038
hsa-miR-200a	hsa-mir-200a	1	20473948
hsa-miR-200a	hsa-mir-200a	1	20418949
hsa-miR-200a	hsa-mir-200a	1	20037478
hsa-miR-200a	hsa-mir-200a	1	19910931
hsa-miR-200a	hsa-mir-200a	1	19703993
hsa-miR-200a	hsa-mir-200a	1	19671845
hsa-miR-200a	hsa-mir-200a	1	19167416
hsa-miR-200a	hsa-mir-200a	1	18829540
hsa-miR-200a	hsa-mir-200a	1	18698484
hsa-miR-200a	hsa-mir-200a	1	18376396
hsa-miR-200a	hsa-mir-200a	1	21389093
hsa-miR-200a	hsa-mir-200a	1	18381893
hsa-miR-200a	hsa-mir-200a	1	18411277
hsa-miR-200a*	hsa-mir-200a	1	21285251
hsa-miR-200a*	hsa-mir-200a	1	20668090
hsa-miR-200a*	hsa-mir-200a	1	20484038
hsa-miR-200a*	hsa-mir-200a	1	20473948
hsa-miR-200a*	hsa-mir-200a	1	20418949
hsa-miR-200a*	hsa-mir-200a	1	20037478
hsa-miR-200a*	hsa-mir-200a	1	19910931
hsa-miR-200a*	hsa-mir-200a	1	19703993
hsa-miR-200a*	hsa-mir-200a	1	19671845
hsa-miR-200a*	hsa-mir-200a	1	19167416
hsa-miR-200a*	hsa-mir-200a	1	18829540
hsa-miR-200a*	hsa-mir-200a	1	18698484
hsa-miR-200a*	hsa-mir-200a	1	18376396
hsa-miR-200a*	hsa-mir-200a	1	21389093
hsa-miR-200a*	hsa-mir-200a	1	18381893
hsa-miR-200a*	hsa-mir-200a	1	18411277
hsa-miR-200b	hsa-mir-200b	1	20668090
hsa-miR-200b	hsa-mir-200b	1	20484038
hsa-miR-200b	hsa-mir-200b	1	20037478
hsa-miR-200b	hsa-mir-200b	1	19910931
hsa-miR-200b	hsa-mir-200b	1	19839049
hsa-miR-200b	hsa-mir-200b	1	19671845
hsa-miR-200b	hsa-mir-200b	1	19654291
hsa-miR-200b	hsa-mir-200b	1	19502803
hsa-miR-200b	hsa-mir-200b	1	19167416
hsa-miR-200b	hsa-mir-200b	1	18829540
hsa-miR-200b	hsa-mir-200b	1	18698484
hsa-miR-200b	hsa-mir-200b	1	18376396
hsa-miR-200b	hsa-mir-200b	1	21389977
hsa-miR-200b	hsa-mir-200b	1	21389093
hsa-miR-200b	hsa-mir-200b	1	18381893
hsa-miR-200b	hsa-mir-200b	1	21079000
hsa-miR-200b	hsa-mir-200b	1	18411277
hsa-miR-200b*	hsa-mir-200b	1	20668090
hsa-miR-200b*	hsa-mir-200b	1	20484038
hsa-miR-200b*	hsa-mir-200b	1	20037478
hsa-miR-200b*	hsa-mir-200b	1	19910931
hsa-miR-200b*	hsa-mir-200b	1	19839049
hsa-miR-200b*	hsa-mir-200b	1	19671845
hsa-miR-200b*	hsa-mir-200b	1	19654291
hsa-miR-200b*	hsa-mir-200b	1	19502803
hsa-miR-200b*	hsa-mir-200b	1	19167416
hsa-miR-200b*	hsa-mir-200b	1	18829540
hsa-miR-200b*	hsa-mir-200b	1	18698484
hsa-miR-200b*	hsa-mir-200b	1	18376396
hsa-miR-200b*	hsa-mir-200b	1	21389977
hsa-miR-200b*	hsa-mir-200b	1	21389093
hsa-miR-200b*	hsa-mir-200b	1	18381893
hsa-miR-200b*	hsa-mir-200b	1	21079000
hsa-miR-200b*	hsa-mir-200b	1	18411277
hsa-miR-200c	hsa-mir-200c	12	21294122
hsa-miR-200c	hsa-mir-200c	12	21224847
hsa-miR-200c	hsa-mir-200c	12	21207483
hsa-miR-200c	hsa-mir-200c	12	20716115
hsa-miR-200c	hsa-mir-200c	12	20705680
hsa-miR-200c	hsa-mir-200c	12	20682048
hsa-miR-200c	hsa-mir-200c	12	20473948
hsa-miR-200c	hsa-mir-200c	12	19935649
hsa-miR-200c	hsa-mir-200c	12	19901913
hsa-miR-200c	hsa-mir-200c	12	19839049
hsa-miR-200c	hsa-mir-200c	12	19671845
hsa-miR-200c	hsa-mir-200c	12	19654291
hsa-miR-200c	hsa-mir-200c	12	19502803
hsa-miR-200c	hsa-mir-200c	12	19435871
hsa-miR-200c	hsa-mir-200c	12	19167416
hsa-miR-200c	hsa-mir-200c	12	18698484
hsa-miR-200c	hsa-mir-200c	12	18483486
hsa-miR-200c	hsa-mir-200c	12	18376396
hsa-miR-200c	hsa-mir-200c	12	17804704
hsa-miR-200c	hsa-mir-200c	12	16929162
hsa-miR-200c	hsa-mir-200c	12	21389977
hsa-miR-200c	hsa-mir-200c	12	21389093
hsa-miR-200c	hsa-mir-200c	12	18381893
hsa-miR-200c	hsa-mir-200c	12	18411277
hsa-miR-200c*	hsa-mir-200c	12	21294122
hsa-miR-200c*	hsa-mir-200c	12	21224847
hsa-miR-200c*	hsa-mir-200c	12	21207483
hsa-miR-200c*	hsa-mir-200c	12	20716115
hsa-miR-200c*	hsa-mir-200c	12	20705680
hsa-miR-200c*	hsa-mir-200c	12	20682048
hsa-miR-200c*	hsa-mir-200c	12	20473948
hsa-miR-200c*	hsa-mir-200c	12	19935649
hsa-miR-200c*	hsa-mir-200c	12	19901913
hsa-miR-200c*	hsa-mir-200c	12	19839049
hsa-miR-200c*	hsa-mir-200c	12	19671845
hsa-miR-200c*	hsa-mir-200c	12	19654291
hsa-miR-200c*	hsa-mir-200c	12	19502803
hsa-miR-200c*	hsa-mir-200c	12	19435871
hsa-miR-200c*	hsa-mir-200c	12	19167416
hsa-miR-200c*	hsa-mir-200c	12	18698484
hsa-miR-200c*	hsa-mir-200c	12	18483486
hsa-miR-200c*	hsa-mir-200c	12	18376396
hsa-miR-200c*	hsa-mir-200c	12	17804704
hsa-miR-200c*	hsa-mir-200c	12	16929162
hsa-miR-200c*	hsa-mir-200c	12	21389977
hsa-miR-200c*	hsa-mir-200c	12	21389093
hsa-miR-200c*	hsa-mir-200c	12	18381893
hsa-miR-200c*	hsa-mir-200c	12	18411277
hsa-miR-203	hsa-mir-203	14	21125666
hsa-miR-203	hsa-mir-203	14	21038317
hsa-miR-203	hsa-mir-203	14	19935649
hsa-miR-205	hsa-mir-205	1	21277012
hsa-miR-205	hsa-mir-205	1	20588024
hsa-miR-205	hsa-mir-205	1	20473948
hsa-miR-205	hsa-mir-205	1	20103531
hsa-miR-205	hsa-mir-205	1	19910931
hsa-miR-205	hsa-mir-205	1	19901913
hsa-miR-205	hsa-mir-205	1	19502803
hsa-miR-205	hsa-mir-205	1	18698484
hsa-miR-205	hsa-mir-205	1	18376396
hsa-miR-21	hsa-mir-21	17	19167416
hsa-miR-21*	hsa-mir-21	17	19167416
hsa-miR-210	hsa-mir-210	11	20716115
hsa-miR-214	hsa-mir-214	1	20716115
hsa-miR-214*	hsa-mir-214	1	20716115
hsa-miR-222	hsa-mir-222	X	20716115
hsa-miR-222*	hsa-mir-222	X	20716115
hsa-miR-23a	hsa-mir-23a	19	21241464
hsa-miR-23a	hsa-mir-23a	19	20716115
hsa-miR-23a*	hsa-mir-23a	19	21241464
hsa-miR-23a*	hsa-mir-23a	19	20716115
hsa-miR-23b	hsa-mir-23b	9	21125666
hsa-miR-23b	hsa-mir-23b	9	21038317
hsa-miR-23b*	hsa-mir-23b	9	21125666
hsa-miR-23b*	hsa-mir-23b	9	21038317
hsa-miR-29c	hsa-mir-29c	1	21125666
hsa-miR-29c	hsa-mir-29c	1	21038317
hsa-miR-29c*	hsa-mir-29c	1	21125666
hsa-miR-29c*	hsa-mir-29c	1	21038317
hsa-miR-34a	hsa-mir-34a	1	20037478
hsa-miR-34a	hsa-mir-34a	1	19167416
hsa-miR-34a*	hsa-mir-34a	1	20037478
hsa-miR-34a*	hsa-mir-34a	1	19167416
hsa-miR-369-5p	hsa-mir-369	14	21125666
hsa-miR-369-5p	hsa-mir-369	14	21038317
hsa-miR-370	hsa-mir-370	14	21125666
hsa-miR-370	hsa-mir-370	14	21038317
hsa-miR-429	hsa-mir-429	1	21277012
hsa-miR-429	hsa-mir-429	1	20668090
hsa-miR-429	hsa-mir-429	1	20484493
hsa-miR-429	hsa-mir-429	1	19910931
hsa-miR-429	hsa-mir-429	1	19671845
hsa-miR-429	hsa-mir-429	1	19167416
hsa-miR-429	hsa-mir-429	1	18829540
hsa-miR-429	hsa-mir-429	1	18698484
hsa-miR-429	hsa-mir-429	1	18376396
hsa-miR-429	hsa-mir-429	1	18381893
hsa-miR-429	hsa-mir-429	1	21079000
hsa-miR-429	hsa-mir-429	1	18411277
hsa-miR-429	hsa-mir-429	1	19854497
hsa-miR-450a	hsa-mir-450a-1	X	21125666
hsa-miR-450a	hsa-mir-450a-2	X	21125666
hsa-miR-450a	hsa-mir-450a-1	X	21038317
hsa-miR-450a	hsa-mir-450a-2	X	21038317
hsa-miR-542-5p	hsa-mir-542	X	21125666
hsa-miR-542-5p	hsa-mir-542	X	21038317
hsa-miR-92a	hsa-mir-92a-1	13	20037478
hsa-miR-92a	hsa-mir-92a-2	X	20037478
hsa-miR-96	hsa-mir-96	7	19167416
hsa-miR-96*	hsa-mir-96	7	19167416

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
517	mRNA cleavage	TRUE	miR-200a	ZEB1 / TCF8	Luciferase assay - mutant MRE	18381893
518	Unknown	FALSE	miR-200a	ZEB1 / TCF8	Luciferase assay	18411277
519	mRNA cleavage	TRUE	miR-200b	ZEB1 / TCF8	Luciferase assay - mutant MRE	18411277
520	mRNA cleavage	TRUE	miR-200c	ZEB1 / TCF8	Luciferase assay - 3'UTR deletion	18381893
701	Unknown	FALSE	miR-429	ZEB1 / TCF8	Luciferase assay	18411277
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000148516		"mesenchymal-epithelial transition (MET), G1-to-S transition "	primary ovarian cancer	down regulated	"lymphocyte, muscle cell, leukocyte, macrophage"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000148516		"mesenchymal-epithelial transition (MET), G1-to-S transition "	metastasis	down regulated	"lymphocyte, muscle cell, leukocyte, macrophage"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000148516		n_a	Alzheimer disease	down regulated	"lymphocyte, muscle cell, leukocyte, macrophage"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000148516		vascular endothelial cells	lung cancer	down regulated	"lymphocyte, muscle cell, leukocyte, macrophage"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000148516		mesenchymal-epithelial transition (MET)	metastasis	down regulated	"lymphocyte, muscle cell, leukocyte, macrophage"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

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Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
2975	mRNA	TCF8	chr10	31647429	31858133	204	mRNA	LOC220930	chr10	31645463	31647965	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

AutismKB 2.0

Annotation Detail for ZEB1

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics