AutismKB 2.0

Annotation Detail for TERF2


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Basic Information Top
Gene Symbol:TERF2 ( TRBF2,TRF2 )
Gene Full Name: telomeric repeat binding factor 2
Band: 16q22.1
Quick LinksEntrez ID:7014; OMIM: 602027; Uniprot ID:TERF2_HUMAN; ENSEMBL ID: ENSG00000132604; HGNC ID: 11729
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
169N6-acetyllysine.
323Phosphoserine.
333Nuclear localization signal (Potential).
368Phosphoserine.
380Phosphoserine.
Location(AA) Modifications Resource
188PhosphothreoninePhospho.ELM 6.0
323Phosphoserine.Swiss-Prot 53.0
323PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
8Phosphoserine(ATM)HMM predict
20Phosphoserine(PKG)HMM predict
28MethylarginineHMM predict
73Phosphotyrosine(EGFR)HMM predict
127Phosphothreonine(MAPK)HMM predict
251Phosphoserine(CK2)HMM predict
323Phosphoserine(MAPK)HMM predict
336N-linkedHMM predict
358Phosphothreonine(PKC)HMM predict
368Phosphoserine(ATM)HMM predict
368Phosphoserine(CK1)HMM predict
370Phosphoserine(IKK)HMM predict
380Phosphoserine(ATM)HMM predict
385O-linkedHMM predict
389O-linkedHMM predict
392O-linkedHMM predict
440Phosphoserine(CK1)HMM predict
443N-linkedHMM predict
481N-linkedHMM predict
493Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005652
  • Location:chr16 67947035-67977373
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 67987566 67987788 222 10304
ETS1 JurkatGSE17954 67976983 67977935 952 86
FOXA1 MCF7GSE15244 67987602 67988375 773 10615
Nanog hESGSE18292 67987559 67987874 315 10343
P300 T0-glioblastomaGSE21026 67977215 67977735 520 102
RARA MCF7GSE15244 67987566 67988375 809 10597
Rb QuiescentGSE19898 67977248 67977523 275 12
TFAP2C MCF7GSE21234 67995785 67996264 479 18651
VDR GM10855-UnstimGSE22484 67976867 67978096 1229 108
hScc1 BcellGSE12603 67987566 67988129 563 10474
hScc1 CdLSGSE12603 67987566 67988057 491 10438
hScc1 CdLSGSE12603 67989328 67990131 803 12356
hScc1 G2GSE9613 67987566 67988375 809 10597
p130 QuiescentGSE19898 67977348 67977532 184 67
p130 SenescentGSE19898 67977389 67977657 268 150
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 67966018 67966282 264 0
CTCF G2GSE9613 67956650 67956898 248 0
CTCF G2GSE9613 67976840 67977583 743 0
H3K4me2 HCT116GSE10453 67976589 67976979 390 0
H3K4me3 colorectalcancer 67976343 67976840 497 0
H3ac HepG2E 67975195 67977004 1809 0
P300 T30-glioblastomaGSE21026 67976573 67978001 1428 0
PHF8 HeLaGSE20725 67976732 67977765 1033 0
PHF8 Hs68minusFBSGSE20725 67976673 67977773 1100 0
PHF8 Hs68plusFBSGSE20725 67976524 67977753 1229 0
Rb GrowingGSE19898 67977205 67977486 281 0
TAF HelaGSE8489 67975692 67977004 1312 0
TAF k562GSE8489 67975764 67977004 1240 0
hScc1 BcellGSE12603 67976720 67977304 584 0
hScc1 CdLSGSE12603 67976804 67977377 573 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018