AutismKB 2.0

Annotation Detail for TFPI


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Basic Information Top
Gene Symbol:TFPI ( EPI,LACI,TFI,TFPI1 )
Gene Full Name: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Band: 2q32.1
Quick LinksEntrez ID:7035; OMIM: 152310; Uniprot ID:TFPI1_HUMAN; ENSEMBL ID: ENSG00000003436; HGNC ID: 11760
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
42O-linked (GalNAc...); partial.
145N-linked (GlcNAc...).
195N-linked (GlcNAc...).
202O-linked (GalNAc...); partial.
203O-linked (GalNAc...).
Location(AA) Modifications Resource
30Phosphoserine (CK2 alpha)Phospho.ELM 6.0
145N-linked (GlcNAc...).Swiss-Prot 53.0
195N-linked (GlcNAc...).Swiss-Prot 53.0
202O-linked (GalNAc...); partial.Swiss-Prot 53.0
203O-linked (GalNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
30Phosphoserine(CK2)HMM predict
30PhosphoserineHMM predict
145N-linkedHMM predict
195N-linkedHMM predict
196N-linkedHMM predict
199Phosphothreonine(CDK)HMM predict
199Phosphothreonine(MAPK)HMM predict
256N-linkedHMM predict
267S-palmitoylHMM predict
283Phosphothreonine(PKC)HMM predict
292ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001032281
  • Location:chr2 188051551-188127463
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 188131000 188131316 316 3695
TAF k562GSE8489 188126245 188128795 2550 57
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 188073846 188074224 378 0
Fos K562GSE19551 188120370 188120841 471 0
Myc K562GSE19551 188120375 188120738 363 0
Nanog ESGSE20650 188092796 188093253 457 0
P300 T0-glioblastomaGSE21026 188125752 188126444 692 0
P300 T30-glioblastomaGSE21026 188120054 188120938 884 0
P300 T30-glioblastomaGSE21026 188125948 188126652 704 0
PolII HeLaGSE12783 188125936 188127793 1857 0
RARA MCF7GSE15244 188073798 188074414 616 0
RARA MCF7GSE15244 188117387 188117760 373 0
STAT1 HeLaGSE12783 188073605 188074614 1009 0
STAT1 HeLaGSE12783 188117133 188118360 1227 0
STAT1 IFNSISSRdata 188117304 188118141 837 0
TFAP2C MCF7GSE21234 188092771 188093159 388 0
hScc1 G2GSE9613 188072972 188074224 1252 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018