AutismKB 2.0

Annotation Detail for TGM1


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Basic Information Top
Gene Symbol:TGM1 ( ICR2,KTG,LI,LI1,TGASE,TGK )
Gene Full Name: transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
Band: 14q12
Quick LinksEntrez ID:7051; OMIM: 190195; Uniprot ID:TGM1_HUMAN; ENSEMBL ID: ENSG00000092295; HGNC ID: 11777
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
68Phosphoserine (By similarity).
92Phosphoserine (By similarity).
95Phosphoserine (By similarity).
Location(AA) Modifications Resource
24PhosphoserinePhospho.ELM 6.0
68Phosphoserine (By similarity).Swiss-Prot 53.0
82PhosphoserinePhospho.ELM 6.0
85PhosphoserinePhospho.ELM 6.0
92Phosphoserine (By similarity).Swiss-Prot 53.0
92PhosphoserinePhospho.ELM 6.0
95Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
22Phosphothreonine(MAPK)HMM predict
22O-linkedHMM predict
22O-linkedHMM predict
22O-linkedHMM predict
24O-linkedHMM predict
24Phosphoserine(MAPK)HMM predict
24Phosphoserine(CDC2)HMM predict
37MethylarginineHMM predict
50S-palmitoylHMM predict
51S-palmitoylHMM predict
69MethylarginineHMM predict
77Phosphothreonine(PKC)HMM predict
92O-linkedHMM predict
93MethylarginineHMM predict
134SulfotyrosineHMM predict
257Phosphotyrosine(EGFR)HMM predict
270N-linkedHMM predict
276SulfotyrosineHMM predict
315MethylarginineHMM predict
341N-linkedHMM predict
351N-linkedHMM predict
370Phosphotyrosine(INSR)HMM predict
370Phosphotyrosine(Syk)HMM predict
461Phosphothreonine(MAPK)HMM predict
471S-palmitoylHMM predict
472S-palmitoylHMM predict
602N-linkedHMM predict
690Phosphothreonine(PKA)HMM predict
747N-linkedHMM predict
776Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000359
  • Location:chr14 23788161-23802255
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 23802553 23803625 1072 834
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata1 K562GSE18868 23795263 23795850 587 0
Gata2 K562GSE18868 23795116 23795944 828 0
H3ac HepG2E 23800219 23800766 547 0
Oct1 H2O2-HelaGSE14283 23798420 23798448 28 0
Oct1 HelaGSE14283 23798421 23798450 29 0
P300 T30-glioblastomaGSE21026 23790590 23791198 608 0
hScc1 BcellGSE12603 23789449 23789770 321 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018