AutismKB 2.0

Annotation Detail for TGM3


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Basic Information Top
Gene Symbol:TGM3 ( MGC126249,MGC126250,TGE )
Gene Full Name: transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
Band: 20p13
Quick LinksEntrez ID:7053; OMIM: 600238; Uniprot ID:TGM3_HUMAN; ENSEMBL ID: ENSG00000125780; HGNC ID: 11779
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
111Phosphotyrosine.
112Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
65O-linkedHMM predict
78N-linkedHMM predict
81Phosphoserine(ATM)HMM predict
95O-linkedHMM predict
99O-linkedHMM predict
119Phosphoserine(ATM)HMM predict
155Phosphotyrosine(INSR)HMM predict
155SulfotyrosineHMM predict
236N-linkedHMM predict
249Phosphoserine(IKK)HMM predict
312Phosphotyrosine(Syk)HMM predict
356Phosphothreonine(MAPK)HMM predict
404N-linkedHMM predict
518N-linkedHMM predict
527N-linkedHMM predict
594N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003245
  • Location:chr20 2224674-2269723
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 2221349 2221754 405 3123
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 2280473 2280758 285 10892
CTCF CD4SISSRdata 2280473 2280758 285 10892
CTCF G2GSE9613 2280406 2280990 584 10975
ER MCF7GSE19013 2278354 2278977 623 8942
Myc K562GSE19551 2275869 2276091 222 6257
Nanog hESGSE18292 2275906 2276073 167 6266
RARA MCF7GSE15244 2278329 2279234 905 9058
Rb QuiescentGSE19898 2285704 2285871 167 16064
TFAP2C MCF7GSE21234 2278448 2278940 492 8971
hScc1 BcellGSE12603 2280406 2280709 303 10834
hScc1 CdLSGSE12603 2280370 2280990 620 10957
hScc1 G2GSE9613 2280442 2280990 548 10993
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 2243548 2244341 793 0
H3ac HepG2E 2262586 2262946 360 0
TFAP2C MCF7GSE21234 2243701 2244140 439 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018